Clinical trials
Liver Cirrhosis clinical trials
Below are recruiting liver cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07438288Recruiting
Predicting Liver Failure in People with Cirrhosis
This study follows people with liver cirrhosis—a condition where the liver is scarred—to see who gets worse or develops sudden liver failure. The goal is to find early warning signs so doctors can help prevent serious problems.
SingaporeAges 18 years+ - NCT06634186Enrolling by invitation
Fiber-rich diet for liver cirrhosis patients
This study tests whether eating more dietary fiber can improve outcomes for people with liver cirrhosis and high blood pressure in the liver (portal hypertension). If you have cirrhosis, adding fiber to your diet might help.
Hanover, Lower SaxonyAges 18 years+ - NCT04801290Recruiting
TIPS procedure for people with worsening liver cirrhosis
This trial studies the TIPS procedure in people with decompensated (worsening) liver cirrhosis to see how it helps. You may be considered if you need a TIPS procedure and can receive care at the study hospital.
Hanover, Lower SaxonyAges 18–99 - NCT07169526Recruiting
Health literacy and confidence in alcohol-related liver cirrhosis
This study looks at how well patients with alcohol-related liver cirrhosis understand health information and feel confident managing their health. It aims to find ways to support patients better.
HanoverAges 18–99 - NCT03080129Recruiting
Study gut microbes and muscle loss in liver cirrhosis
This study looks at the gut microbiome (the helpful bacteria in your gut) and muscle loss (sarcopenia) in people with liver cirrhosis. It may help researchers understand what changes in the gut and body can go along with getting weaker, so better treatments can be developed.
GrazAges 18–100 - NCT06169592Recruiting
Bleeding and Clotting Risks After Living Donor Liver Transplant
This study is for people with severe liver cirrhosis who are getting a liver transplant from a living donor. It looks at the risk of bleeding or clotting problems after the transplant, to help doctors better manage these risks.
TashkentAges 18–70 - NCT06950788Recruiting
Glucose changes in cirrhosis patients around liver transplant
This study looks at how the body processes sugar (glucose) in people with cirrhosis who are waiting for a liver transplant. It aims to track changes in blood sugar control before and after transplant, which may help improve care for patients with liver disease.
Chicago, IllinoisAges 18–75 - NCT06814626RecruitingPhase 3
Nutrition therapy for muscle loss in cirrhosis with fluid buildup
This trial tests whether a special nutrition plan can help treat muscle loss in people with liver cirrhosis who also have fluid buildup that doesn't improve with standard treatment. It aims to improve strength and outcomes after a procedure to place a shunt in the liver.
PalermoAges 18–80 - NCT04502719Recruiting
Testing nutrition screening in people with liver cirrhosis
This study compares different ways of checking nutrition problems in people with liver cirrhosis. It may help doctors choose the best screening tool to spot risk earlier and guide care.
Barcelona, CataloniaAges 18–100 - NCT05899231Recruiting
Online strengthening program while you wait for a liver transplant
This trial tests an online prehabilitation program (strength and fitness training delivered digitally) to help people who are likely to need a liver transplant become stronger before transplant. It may benefit people who feel “frail” or “pre-frail,” since improving strength before surgery can help recovery.
Calgary, AlbertaAges 18 years+ - NCT06576934Recruiting
Early TIPS for liver cirrhosis with ascites
This study tests whether placing a small tube (called a TIPS) early in the liver can help people with cirrhosis who have their first episode of moderate to severe belly fluid buildup. The goal is to see if this early procedure improves outcomes compared to standard care.
Freiburg im BreisgauAges 18–80 - NCT07585890Recruiting
Liver Transplant Outcomes With Machine Preservation in Europe
This study collects information about how livers do after transplantation when they've been preserved using machine perfusion—a technique that keeps donor livers in better condition before surgery. Researchers want to understand which preservation methods work best to improve transplant success across Europe.
ViennaAges 18 years+ - NCT07437755Recruiting
Guiding blood transfusions during procedures for cirrhosis
This study compares a special blood test (thrombelastometry) to standard tests to decide when to give blood products before invasive procedures in people with advanced liver cirrhosis. The goal is to see which method leads to better use of blood products and fewer complications.
Iași, IaşiAges 18 years+ - NCT07561138Recruiting
Nutrition and Exercise Training Before Liver Transplant
This study tests whether eating better and doing gentle exercise before your liver transplant can help you stay healthier and recover better after surgery. You'll work with a nutrition expert and exercise specialist to prepare your body for transplant.
Athens, AtticaAges 18–70 - NCT06153082Recruiting
Comparing two blood clotting tests for cirrhosis patients with bleeding
This trial compares two tests (ROTEM and TEG) that help doctors decide which blood products to give to cirrhosis patients with active stomach or intestinal bleeding that is not from varices. The goal is to find which test works better.
New Delhi, National Capital Territory of DelhiAges 18–80 - NCT05095714Recruiting
Fast MRI for close monitoring of high-risk liver cancer
This trial studies a faster MRI scan to help track early liver cancer in people who have cirrhosis and are considered high risk. It may improve how often and how well doctors can look for changes without using longer imaging sessions.
BondyAges 18 years+ - NCT05475015Recruiting
3D MRI scan to assess liver scarring and pressure
This study tests whether a special 3D MRI scan (3D-MRE) can measure liver scarring and the high pressure in the liver called portal hypertension. It may help your team use imaging to understand how severe your liver disease is, especially when a pressure test (HVPG) is being considered.
Shenyang, LiaoningAges 18–75 - NCT07108075Recruiting
Testing metformin and carvedilol for cirrhosis with variceal bleeding
This trial tests whether adding metformin to carvedilol (a standard drug) lowers liver pressure more than carvedilol alone in people with cirrhosis who have had variceal bleeding. The goal is to prevent future bleeding.
New Delhi, National Capital Territory of DelhiAges 18–75 - NCT07418008Recruiting
Thinking and memory study for people with liver cirrhosis
This study is creating a new test to measure thinking and memory problems in people with liver cirrhosis. It may help doctors find these problems earlier.
Ambāla, HaryanaAges 18–75 - NCT05431946Enrolling by invitation
Palliative care support for people with liver cirrhosis
This trial studies a palliative care approach—comfort-focused support aimed at improving quality of life—for people with liver cirrhosis. It may help by addressing symptoms and planning care together with you and your family.
EsbjergAges 18 years+ - NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+ - NCT05325424Recruiting
Laparoscopic spleen surgery for people with cirrhosis
This study looks at whether removing the spleen using keyhole surgery can improve “liver reserve function” in people with cirrhosis. It may be considered for patients who have an enlarged spleen and very low platelets, but it also has several safety exclusions.
Yangzhou, JiangsuAges 18 years+ - NCT05325437Recruiting
Laparoscopic spleen surgery to protect liver function in cirrhosis
This trial looks at whether a minimally invasive spleen surgery (with a specific vein-disconnection procedure) can better protect liver function in people with cirrhosis who have had variceal bleeding. It may help reduce stress on the liver after treatment, but you must meet several safety criteria.
Yangzhou, JiangsuAges 18 years+ - NCT05490888RecruitingPhase 1
Dose study of PHIN-214 for mild to moderate cirrhosis
This Phase 1 study tests how the medicine PHIN-214 behaves in the body and what dose is tolerable in people with Child-Pugh A or B liver cirrhosis. It may help doctors plan safer dosing for future studies.
Chandler, ArizonaAges 18–75
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Common questions
- Are there clinical trials for liver cirrhosis?
- Yes. Clin2 currently lists 197 recruiting liver cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.