Clinical trials
Liver Cirrhosis clinical trials
Below are recruiting liver cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02423395RecruitingPhase 3
Orphenadrine for muscle cramps in people with cirrhosis
This trial tests whether orphenadrine (a medication used to reduce muscle cramping) can lessen muscle cramps in people who have cirrhosis of the liver. It may help if your cramps happen often, but you must avoid certain medication conflicts and health situations.
TantaAges Any age - NCT06455280RecruitingPhase 1
A study of Siplizumab for autoimmune liver disease patients awaiting transplant
This trial tests a drug called Siplizumab in people with autoimmune hepatitis or primary sclerosing cholangitis who are on the liver transplant waitlist. It aims to see if the drug can help manage their condition before and after transplant.
New York, New YorkAges 18 years+ - NCT07685353Recruiting
Genes and graft fat after liver transplant study
This study looks at how genetic differences between liver donors and recipients affect fat buildup in the new liver after transplantation. It may help doctors understand why some transplanted livers develop steatosis (fatty liver) after the surgery.
New DelhiAges 18 years+ - NCT03208868Recruiting
Amino acid drink to help rebuild muscle in cirrhosis
This trial tests whether a special mix of amino acids (building blocks for muscle) can help reverse muscle loss in people with cirrhosis. It aims to improve muscle health while keeping you safe from known complications of liver disease.
Cleveland, OhioAges 18–70 - NCT07172035Recruiting
TIPS and liver recovery in decompensated cirrhosis
This trial studies whether a procedure called TIPS (a stent placed in the liver to improve blood flow) can help people with advanced liver disease regain better liver function. It is for patients who have had complications like severe bleeding from the stomach or difficult-to-control fluid buildup (ascites).
ChangshaAges 18–80 - NCT04873102RecruitingPhase 2
Danazol for low blood counts in some people with cirrhosis
This Phase 2 study tests danazol to improve low blood counts (low white blood cells and/or low platelets) in people with certain types of cirrhosis. It also looks at who may benefit, especially those with specific inherited blood-telomere changes.
Los Angeles, CaliforniaAges 18 years+ - NCT05166499Recruiting
Amino acids to help rebuild muscle in liver cirrhosis
This trial tests whether a special amino-acid supplement can help reverse muscle loss in people with cirrhosis (scarring of the liver). It may help maintain or improve muscle strength and overall function, but eligibility depends on your liver status and overall health.
Cleveland, OhioAges 21–65 - NCT05346393Recruiting
TIPS procedure for kidney failure in people with cirrhosis
This trial studies whether a liver procedure called TIPS can help people with cirrhosis who develop sudden kidney failure (HRS-AKI). It aims to improve kidney function and overall outcomes, but participation depends on several safety checks.
AachenAges 18–80 - NCT05729438Recruiting
Nutritional assessment in people with liver cirrhosis
This study focuses on assessing nutrition in adults living with liver cirrhosis. The goal is to understand nutritional needs and how assessment may support care.
Bucharest, București - Sector1Ages 18–75 - NCT05982769Recruiting
Exercise for cirrhosis patients
This study tests whether a supervised exercise program can help people with cirrhosis (scarred liver) feel stronger and improve their health. You'll be asked to exercise regularly and have tests to see how your muscles and liver respond.
Cleveland, OhioAges 21–65 - NCT06092385Recruiting
Swiss cirrhosis study for liver patients and controls
This study compares patients with advanced liver scarring (cirrhosis) to healthy controls to learn more about the condition. It may help researchers better understand and manage liver disease.
Lugano, Canton TicinoAges 18 years+ - NCT06174272Recruiting
Better care after hospital for liver swelling
This trial tests a program to help people with cirrhosis and severe fluid swelling get better care after leaving the hospital. It focuses on guiding you through treatment with water pills and managing fluid buildup at home.
Hershey, PennsylvaniaAges 18 years+ - NCT06525623Recruiting
Early albumin for kidney injury in cirrhosis
This study tests whether giving a common fluid (albumin) early can help protect the kidneys in people with advanced liver disease who have a sudden kidney injury. It aims to see if this simple treatment can improve recovery and prevent the need for dialysis.
Boston, MassachusettsAges 18 years+ - NCT07031843Recruiting
New prediction model study for liver cirrhosis
This study is exploring a new way to predict how liver cirrhosis will progress. It may help doctors better understand and manage the condition.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT03267615Recruiting
Study in advanced liver scarring using pressure and stiffness tests
This study looks at people over 18 who have advanced, long-term liver scarring. It uses specialized measurements of liver stiffness and pressure to confirm eligibility and may help doctors better understand this condition.
ViennaAges 18–100 - NCT07715500Recruiting
MRI of Bile Ducts in Living Liver Donors
This study uses an MRI scan to look at the bile ducts in healthy people who want to donate part of their liver. The goal is to see if the scan can help predict and prevent bile duct problems for the person receiving the liver.
New DelhiAges 18–55 - NCT06544863Recruiting
Better support for cirrhosis and liver transplant patients
This study tests a new care support program for people with cirrhosis or who have had a liver transplant. It aims to improve how patients are followed and helped at the hospital.
ParisAges 18 years+ - NCT06773260Enrolling by invitation
Using liver stiffness to predict varices in advanced liver cancer
This trial uses a simple ultrasound test (measuring liver and spleen stiffness) to predict if a patient with cirrhosis and advanced liver cancer has enlarged veins in the esophagus. The goal is to avoid unnecessary invasive procedures like endoscopy.
Bari, ItalyAges 18–80 - NCT07205471Recruiting
Partial spleen removal via laparoscopy for cirrhosis-related hypersplenism
This study is testing a keyhole surgery to remove part of an enlarged spleen in people with cirrhosis. It aims to improve low blood counts and reduce the risk of further bleeding from stomach or esophagus veins.
Yangzhou, JiangsuAges 18 years+ - NCT05338294Recruiting
Tested surgery to help immune function in cirrhosis
This study looks at whether a type of keyhole spleen surgery plus cutting a large vein can improve immune function in people with cirrhosis. It may help reduce immune problems that can happen after complications like bleeding from varices (enlarged veins in the esophagus/stomach).
Yangzhou, JiangsuAges 18 years+ - NCT05502198Recruiting
How muscle loss matters in advanced liver disease
This study looks at how loss of muscle strength or mass (sarcopenia) relates to advanced liver disease. It may help doctors understand which patients are at higher risk and could guide future care choices.
EksjöAges 18 years+ - NCT06039696Recruiting
Testing a new way to find infections in liver disease patients
This trial uses a DNA test to better detect infections in people with advanced liver disease who are hospitalized. It may help doctors find the right treatment faster.
Guangzhou, GuangdongAges 18–80 - NCT06248580Recruiting
Finding HDV in Turkey Study
This trial is looking for adults in Turkey who have had a hepatitis B infection (HBsAg positive) for at least 6 months. The goal is to see if they also have a hepatitis D virus (HDV) infection. This may help doctors better understand and treat these infections.
AnkaraAges 18 years+ - NCT07429864Recruiting
Bulevirtide for hepatitis D: bile acids and gut bacteria
This study looks at how Bulevirtide, a treatment for hepatitis D, affects bile acids and gut bacteria. It may help patients with chronic HDV and stable liver disease who are already on HBV therapy.
RomaAges 18 years+
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Common questions
- Are there clinical trials for liver cirrhosis?
- Yes. Clin2 currently lists 197 recruiting liver cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.