Clinical trials
Liver Cirrhosis clinical trials
Below are recruiting liver cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07469319Recruiting
Liver cancer screening for people with cirrhosis
This study tests whether offering an ultrasound and a blood test (alpha-fetoprotein) every 6 months can help find liver cancer early in people with cirrhosis (scarred liver) caused by conditions other than hepatitis B or C. The goal is to reduce deaths from liver cancer in this group.
Aarhus, Central JutlandAges 40–79 - NCT06778317Recruiting
Blood test to predict liver cancer in cirrhosis patients
This trial tests if a simple blood test can help predict who with cirrhosis might develop liver cancer, so doctors can monitor and treat those patients earlier.
Vandœuvre-lès-NancyAges 18 years+ - NCT05548452RecruitingPhase 1/Phase 2
Microbiota transplant for advanced liver disease from alcohol
This trial tests whether giving a healthy mix of gut bacteria (an intestinal microbiota transplant) can improve outcomes in people with advanced liver disease caused by ongoing alcohol use. It may help rebalance the gut and support liver health, but participation depends on strict safety and diagnosis criteria.
Richmond, VirginiaAges 18 years+ - NCT07241195Recruiting
Fatty Liver Study in Older Adults
This study follows older adults with fatty liver disease to understand how their metabolism changes over time and how it affects their overall health. It helps researchers learn more about the condition and its impact on the body outside the liver.
Hangzhou, ZhejiangAges 65–100 - NCT06863012Recruiting
Measuring liver pressure with endoscopy: a new method
This trial compares a newer, less invasive method (using an endoscope) to measure pressure in the liver's blood vessels with the standard technique. It may help people with liver disease or suspected cirrhosis better understand their condition.
Barcelona, BarcelonaAges 18–85 - NCT06121492Enrolling by invitationPhase 3
Amino Acid Drink for Muscle Loss in Liver Cirrhosis
This study tests whether taking a daily drink of branched-chain amino acids (a type of protein) can help people with liver cirrhosis who have lost muscle strength and mass. It may help improve muscle size and function.
Bangkok, BangkokAges 18–85 - NCT04446832Recruiting
Vaccine study for people waiting for liver transplant
This study tests a vaccine strategy for people who are being evaluated and waiting for a liver transplant. The goal is to see how well the immune system responds and how the results are interpreted before transplant.
LyonAges 18 years+ - NCT06624189Enrolling by invitation
Liver cancer screening decision support for cirrhosis patients
This trial tests a tool to help doctors and patients decide when to screen for liver cancer. It is for people with cirrhosis who have not had imaging in the last 6 months.
New York, New YorkAges 18 years+ - NCT05477277Recruiting
MRI testing during liver transplant evaluation
This study looks at whether having an MRI scan during liver transplant planning helps predict who may have worse outcomes or higher risk of death. It focuses on adults with severe liver disease who are already being considered for a transplant.
Phoenix, ArizonaAges 18 years+ - NCT06755632Recruiting
Hepatic fibrosis or cirrhosis screening trial
This trial screens for liver scarring (fibrosis) or severe scarring (cirrhosis) caused by hepatitis B or C. It aims to find people who may benefit from further care or treatment.
BobignyAges 18 years+ - NCT03569826Recruiting
Study for primary biliary cholangitis and autoimmune hepatitis
This study is for people diagnosed with primary biliary cholangitis or autoimmune hepatitis. It aims to learn more about these autoimmune liver conditions and may help guide better care in the future.
Calgary, AlbertaAges 18 years+ - NCT06458998Enrolling by invitation
Improving cancer screening for veterans
This study looks at ways to help veterans get screened for liver cancer (hepatocellular carcinoma) and colorectal cancer. The goal is to see if certain programs or tools can make it easier for veterans to complete these important cancer screenings.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT04106518Recruiting
Genetics study of alcohol-related liver disease and cirrhosis
This study looks at genetic differences in people with alcohol-related liver illness, including a recent jaundice episode (alcoholic hepatitis). By following people over time, it may help doctors better predict illness and understand why some people develop worse liver problems.
AngersAges 18 years+ - NCT06831565Recruiting
Comparing two blood-transfusion strategies for liver patients before procedures
This trial tests whether using a slightly different target on a blood-clotting test (ROTEM) can reduce the need for blood transfusions in people with liver disease who need a procedure. If you have cirrhosis or ACLF with severe clotting problems, this study may help your doctors decide how much blood product to give you before the procedure.
New Delhi, National Capital Territory of DelhiAges 18–75 - NCT05463796Recruiting
Prevention and early detection for people at high cancer risk
This study looks at surveillance (watching closely), prevention, and early “interception” steps to lower the chance that cancer will develop or be found later. It is for people with genetic risk, past cancer treatment exposures, strong family history, or certain early pre-cancer or high-risk conditions.
Boston, MassachusettsAges Any age - NCT07042919RecruitingPhase 1/Phase 2
Zanzalintinib for advanced liver cancer after prior treatment
This trial tests a new drug called zanzalintinib for people with advanced liver cancer (HCC) that can't be treated with surgery. You may join if your cancer has gotten worse after at least one prior treatment, or you couldn't tolerate that treatment.
Chicago, IllinoisAges 18 years+ - NCT06632457RecruitingPhase 3
Survodutide for NASH/MASH cirrhosis: a phase 3 trial
This study tests an investigational drug called survodutide for people with a type of fatty liver disease (NASH or MASH) that has progressed to cirrhosis. The goal is to see if it can improve liver health.
Peoria, ArizonaAges 18 years+ - NCT07553663RecruitingPhase 1
Testing a new liver disease treatment for fatty liver
This study tests how your body processes a new medication called miricorilant, designed to help people with fatty liver disease (MASH). You'll have liver scans or recent biopsy results and metabolic conditions like diabetes or high blood pressure.
San Antonio, TexasAges 18–75 - NCT06911619Recruiting
Nutrition support for liver transplant patients
This study tests whether nutritional support can help reduce frailty in patients waiting for a liver transplant. It aims to improve strength and overall health before surgery.
LyonAges 18 years+ - NCT06948565Recruiting
Cirrhosis patients in the ICU: a 10-year review
This study looks back at medical records of people with cirrhosis who were treated in an intensive care unit (ICU) over the last 10 years. Researchers want to understand what factors affect their recovery and outcomes.
BesançonAges Any age - NCT06840652Enrolling by invitation
Baclofen for alcohol withdrawal in liver disease
This trial tests if baclofen, a medicine for alcohol dependence, is safe and works for people with chronic liver disease who are actively drinking. It may help you stop drinking alcohol safely.
Sabadell, BarcelonaAges 18–75 - NCT07299110Recruiting
Whey vs. egg protein for ammonia levels in liver cirrhosis
This trial compares how whey protein and egg white protein affect ammonia levels in people with cirrhosis caused by alcohol. The goal is to see which protein source is safer for your liver.
New DelhiAges 18–70 - NCT06060769Recruiting
MRI risk assessment for liver cancer in chronic liver disease
This study uses special MRI scans to better predict liver cancer risk in people with chronic liver disease. It may help doctors identify high-risk patients earlier and improve monitoring.
Zhuhai, GuangdongAges 18 years+
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Common questions
- Are there clinical trials for liver cirrhosis?
- Yes. Clin2 currently lists 197 recruiting liver cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.