Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06252753Recruiting
Observational study of durvalumab for liver and bile duct cancer
This study looks at how well durvalumab (Imfinzi) works for people with liver or bile duct cancer. It follows your treatment as part of regular care to gather more information.
Birmingham, AlabamaAges 18–130 - NCT07046819RecruitingPhase 2
Tirzepatide for liver disease linked to alcohol use
This trial tests if tirzepatide, a medication that helps with weight and blood sugar, can improve liver health in people with alcohol use disorder who also have fatty liver disease. It aims to reduce liver fat and related risks.
Bethesda, MarylandAges 21–100 - NCT06581146Recruiting
Liver health study for boys with XLMTM
This study looks at how the liver works in boys with a serious muscle condition called XLMTM. It checks whether their liver is healthy, which may help doctors better understand the condition and guide future treatments.
Santa Monica, CaliforniaAges Up to 17 years - NCT06993454Recruiting
Exercise and blood sugar in type 2 diabetes with fatty liver
This study looks at how a single session of exercise affects the body's natural sugar production in people with type 2 diabetes and fatty liver. It may help us find better ways to control blood sugar and treat fatty liver.
Orlando, FloridaAges 25–55 - NCT07550088RecruitingPhase 2
Combination therapy for colorectal cancer with liver tumors
This study tests a combination of three drugs for patients with colorectal cancer that has spread to the liver. The goal is to see if this combination can shrink tumors and help patients live longer.
La Jolla, CaliforniaAges 18 years+ - NCT07527910RecruitingPhase 2
Study of ALN-PNP with or without tirzepatide for fatty liver disease
This trial tests a new drug, ALN-PNP, alone or with tirzepatide in people with a specific genetic type of fatty liver disease. It aims to see if the combination reduces liver fat.
Coronado, CaliforniaAges 18–75 - NCT03481829Recruiting
Long-term study tracking health factors from pregnancy
This study follows pregnant mothers and their babies for years to understand how early life factors can affect health later. If you qualify, you and your child(ren) will be asked to stay in the research study for at least 3 years after delivery.
Phoenix, ArizonaAges 1 day–99 years - NCT07751783Recruiting
Exercise program for cancer survivors
This trial helps people who have finished cancer treatment start a supervised exercise routine to improve their health. It tests whether a structured program with professional guidance is safe and helpful.
Kaohsiung, TaiwanAges 18–80 - NCT06371924Recruiting
Machine perfusion for livers from donation after circulatory death
This study tests a new way to preserve donated livers (called machine perfusion) after they are recovered from donors who died from circulatory causes. It aims to see if this method helps the liver work better before transplant.
BirminghamAges 18 years+ - NCT05717842Recruiting
Kidney and liver transplant candidates get a scan at surgery
This trial studies whether a specific scan taken around the time of a combined liver-and-kidney transplant can help doctors assess the kidney(s) that will be used. You might be eligible if you are already listed for both transplants and can safely complete the scan.
Indianapolis, IndianaAges 18 years+ - NCT05327478Recruiting
Compare treatments for controlled donation after circulatory death
This trial compares different care approaches for adult donors in a specific type of controlled donation after the heart stops. It aims to find which approach best supports organ/tissue use after donation.
Rotterdam, South HollandAges 50–75 - NCT05255978Recruiting
Follow-up study for hepatitis B with fatty liver
This observational study looks at people with chronic hepatitis B who also have fatty liver (non-alcoholic fatty liver disease). It follows how their liver health changes over time and may help doctors understand outcomes and risk factors.
Wuhan, HubeiAges 18 years+ - NCT07023354RecruitingPhase 1
Study of BI 1291583 in people with and without liver problems
This trial tests how a new medicine, BI 1291583, enters the blood in people who have different levels of liver function (from normal to mild, moderate, or severe liver problems). It helps doctors understand if the dose needs to be adjusted for liver health.
Rialto, CaliforniaAges 18–80 - NCT04715191RecruitingPhase 1
CAR T therapy for GPC3-positive pediatric solid tumors
This Phase 1 study tests a customized immune-cell treatment (CAR T cells) made to recognize GPC3, a marker found on some tumors. It’s designed for children and young people whose solid tumors have not been cured by standard treatment and who can safely receive this therapy.
Houston, TexasAges 1–21 - NCT07060638RecruitingPhase 2
Combination therapy for severe alcoholic hepatitis
This trial tests a combination of treatments for people with severe alcohol-related liver disease (alcoholic hepatitis) that has not responded to standard care. The goal is to improve liver function and help you stop drinking.
Indianapolis, IndianaAges 18–70 - NCT06867419Recruiting
Metabolic effects on fatty liver disease score
This study looks at how certain features of your metabolism affect a simple score (called the FAST score) in people with fatty liver disease (MASLD). It aims to help doctors better understand and manage the condition.
Tanta, GharbyeaAges 18 years+ - NCT06777914Recruiting
Genes linked to rare liver disease and cancer risk
This study looks at whether certain family-related genes make people more likely to develop liver or bile duct cancers without a clear cause. If you had surgery or a transplant for one of these cancers and have had unexplained high liver enzymes or itching, this trial may help find genetic clues.
Bologna, BolognaAges 1 year+ - NCT06448195RecruitingPhase 4
Growth Hormone for Fatty Liver After Pituitary Surgery
This trial tests whether growth hormone therapy can improve liver health and metabolic function in people who have fatty liver after pituitary tumor surgery. It is for adults with growth hormone deficiency who have excess fat in their liver.
ShanghaiAges 18–60 - NCT06311942RecruitingPhase 4
Comparing triple vs. dual therapy after liver surgery for liver cancer
This trial tests whether adding a third drug to standard two-drug therapy after liver surgery helps prevent liver cancer from returning. It is for people who have a specific blood vessel pattern in their tumor, called VETC, seen on a special stain.
Wuhan, HubeiAges 18–75 - NCT06181409Recruiting
New scans to detect liver disease complications
This study uses two types of scans (MRI and ultrasound) to check for high pressure in the veins of your liver. It may help doctors find problems earlier without invasive tests.
Montreal, QuebecAges 18 years+ - NCT06044909Recruiting
Guiding liver surgery with combined images
This trial tests a new method that combines different medical images (CT, MRI, ultrasound) to help guide surgeons during laparoscopic (keyhole) liver surgery. It may make the surgery more precise and safer.
Saint-EtienneAges 18 years+ - NCT05705557Recruiting
Test of a clip system during open liver surgery
This trial studies a new clip system (ABSOLOK™) used during open liver operations. It aims to improve how surgeons control or manage parts of the liver during surgery.
Roma, RMAges 18 years+ - NCT05265208RecruitingPhase 2
Radiation plus chemo after liver surgery for bile duct cancer
This trial studies giving a special internal radiation treatment along with capecitabine (a chemotherapy) for liver cancer related to bile ducts, after planned surgical removal. It may help improve control of the cancer in cases where surgeons think the edges of the removed tumor may be too close.
Rennes, Brittany RegionAges 18 years+ - NCT04906434RecruitingPhase 1
Study of ABSK-011 for advanced solid tumors
This early-phase study tests how safe ABSK-011 is, what side effects it causes, and how the body processes the drug. It may help certain patients with advanced solid cancers (including some liver cancer cases) whose tumors have specific test results.
Phoenix, ArizonaAges 18–75
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.