Clinical trials
Liver clinical trials
Below are recruiting liver clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05098197RecruitingEarly Phase 1
Study of TIL cell therapy for advanced liver, bile, or pancreas cancer
This trial studies a treatment called TIL therapy, which uses your own immune cells grown from a tumor sample, to treat advanced cancers of the liver/bile ducts or pancreas. It’s mainly for people whose standard treatments have already failed (or none exist), and who can safely provide tumor tissue for the cell preparation.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04476563Recruiting
Study liver injury from checkpoint cancer immunotherapy
This study looks at why some people develop liver inflammation after checkpoint inhibitor cancer treatment, called checkpoint inhibitor–induced liver injury (ChILI). It compares people with ChILI to similar cancer patients who are starting the same type of immunotherapy, to better understand and track these liver injury events.
NottinghamAges 18 years+ - NCT04343430Recruiting
Hospital study for fluid buildup in heart failure with preserved heart function
This study looks at how well doctors can assess fluid buildup before you leave the hospital if you have a type of heart failure called “preserved ejection fraction.” It may help improve decisions about when and how safely people are discharged.
Vandœuvre-lès-NancyAges 18 years+ - NCT04523701RecruitingPhase 3
Testing a “white test” to find bile ducts during liver surgery
This trial studies whether a simple “white test” using a special lipid (fat-like) solution can help the surgical team spot open bile ducts early during liver removal. Finding them sooner may help prevent bile leakage after liver surgery.
AarauAges 18 years+ - NCT04343443Recruiting
Test whether a lung ultrasound helps discharge planning after heart failure
This study looks at people hospitalized for worsening heart failure with weaker pumping (reduced ejection fraction). It tests whether a lung ultrasound evaluation near discharge can improve how doctors decide it is safe to send you home.
Vandœuvre-lès-NancyAges 18 years+ - NCT03686137Recruiting
Liver surgery database study for liver tumors
This study collects information from people having liver surgery for a non-cancerous tumor or for liver cancer (primary or cancer that spread to the liver). It doesn’t usually add treatment—your care is documented to help doctors learn and improve future decisions.
Marseille, Bouches Du RhoneAges 18 years+ - NCT07120906Recruiting
Augmented reality guidance for MRI liver procedures
This study tests a new augmented reality system to help doctors place needles in the liver during MRI scans for biopsies or ablation (heat to destroy tumors). The goal is to see if it improves accuracy and speed.
Jacksonville, FloridaAges 18–90 - NCT07172035Recruiting
TIPS and liver recovery in decompensated cirrhosis
This trial studies whether a procedure called TIPS (a stent placed in the liver to improve blood flow) can help people with advanced liver disease regain better liver function. It is for patients who have had complications like severe bleeding from the stomach or difficult-to-control fluid buildup (ascites).
ChangshaAges 18–80 - NCT07173868Recruiting
PET scans for advanced breast cancer treatment planning
This trial tests whether a special PET scan (FDG PET-CT) can better track how well treatment is working for people with advanced breast cancer. It may help doctors choose the best therapy and monitor response over time.
Seoul, Gannam-guAges 19 years+ - NCT07440511Recruiting
Spleen stiffness test for advanced liver scarring
This study tests a new way to measure liver scarring using a non-invasive ultrasound of the spleen (spleen stiffness measurement). It's for people with fatty liver disease (MASLD) who have advanced fibrosis (scarring) to see if this method can accurately detect the severity of liver damage.
RomeAges 18 years+ - NCT03310905Recruiting
Abdominal wall transplant for people needing multi-organ transplant
This study evaluates an abdominal wall transplant (replacing the front belly/tissue) done along with another organ transplant. It may help people who need a specialized transplant approach, but it’s only for certain candidates at Duke who meet strict safety and cancer, pregnancy, and anesthesia requirements.
Durham, North CarolinaAges 18–65 - NCT06324396RecruitingPhase 1
Improving drug dosing for single ventricle patients with liver disease
This trial studies how the drugs sildenafil and pravastatin work in people with a single ventricle heart condition who have had the Fontan surgery and may have related liver problems. The goal is to find the best doses based on liver function.
Kansas City, MissouriAges 8 years+ - NCT06327308RecruitingPhase 1
MRI study for heart health in liver transplant candidates
This study uses a special heart MRI to check for a heart condition called cirrhotic cardiomyopathy in people waiting for a liver transplant. The results may help doctors better understand and treat heart problems in patients with cirrhosis.
BesançonAges 18–70 - NCT01212250Recruiting
Carvedilol to prevent esophagus bleeding in cirrhosis
This trial tests whether carvedilol can prevent the first development of swollen veins (varices) in the esophagus in people with cirrhosis who do not have them yet. It may help lower the risk of future bleeding from those veins.
New Delhi, National Capital Territory of DelhiAges 18–75 - NCT06355895Recruiting
Liver size and radiation therapy for abdominal cancers
This study looks at how changes in liver size affect the planning and delivery of radiation therapy for cancers in the upper abdomen, such as pancreatic, bile duct, or liver cancer. It aims to improve treatment accuracy.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06844357RecruitingPhase 2/Phase 3
New embolization vs standard for liver cancer
This trial tests a new embolization treatment (TATE) against standard therapy for people with intermediate-stage liver cancer that hasn't spread. The goal is to see if TATE works better at controlling the tumor.
Nanjing, JiangsuAges 18 years+ - NCT06387745Recruiting
Checking liver health with a new device
This study tests a new device called Hepatoscope that measures your liver health without a needle. It may be a good option if you have liver problems, diabetes, or metabolic syndrome and want a simple, noninvasive check.
Edegem, AntwerpAges 18–80 - NCT05428267Recruiting
Sexual function study for people with cirrhosis
This study looks at sexual dysfunction in people who have cirrhosis (scarring of the liver). It may help researchers understand causes and better care for sexual problems in this condition.
ParisAges 18 years+ - NCT05089149Recruiting
Check how lung ultrasound helps manage heart failure congestion
This study looks at people with long-term worsening heart failure who are coming to the hospital for a planned visit, to see how checking “congestion” (fluid buildup) may guide care. It may help the team understand whether lung ultrasound can better assess who needs treatment changes.
Vandœuvre-lès-NancyAges 18 years+ - NCT05097898Recruiting
Check fluid buildup in heart failure with normal pumping
This study evaluates how well doctors can assess “fluid congestion” in people with chronic heart failure where the heart’s squeezing is still preserved. It may help improve how patients are monitored during hospital visits.
Vandœuvre-lès-NancyAges 18 years+ - NCT07062380Recruiting
AI tool to predict liver cancer return after surgery
This study uses an AI tool to predict how liver cancer might come back after surgery. It is for people with early-stage liver cancer who are already scheduled for surgery and have recent MRI scans.
Wuhan, HubeiAges 18–75 - NCT07335601RecruitingPhase 2
Resmetirom for liver health after transplant in MASH patients
This trial tests an experimental drug, resmetirom, to see if it can help people who have had a liver transplant for MASH and now have fatty buildup in their new liver. It may also help people who had a transplant for other reasons but developed fatty liver afterward. The study focuses on those with moderate to advanced liver scarring (F2-F3).
La Jolla, CaliforniaAges 18–75 - NCT07185932RecruitingEarly Phase 1
Rifaximin for fatty liver with metabolic issues
This trial tests if rifaximin, a gut-targeted antibiotic, can help people with fatty liver disease who also have metabolic problems like obesity or diabetes. You need a recent fatty liver diagnosis and a liver fat level of at least 8% on an MRI scan.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07507643RecruitingPhase 3
Steroid treatment before liver surgery study
This study tests if a steroid called methylprednisolone can help people recovering from major liver surgery. It aims to see if it reduces inflammation and improves outcomes.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for liver?
- Yes. Clin2 currently lists 1,253 recruiting liver studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.