Clinical trials
Living Donor Liver Transplantation clinical trials
Below are recruiting living donor liver transplantation clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07273448Enrolling by invitation
ABO-mismatched living donor liver transplant study
This study looks at the results of liver transplants from living donors with a different blood type than the recipient. It aims to understand how well patients do after this type of transplant.
Ages Any age - NCT06875232Enrolling by invitation
Comparing CT and MRI scans for live liver donors
This study looks at how well CT scans and MRI scans (MRCP) show the blood vessels in the liver before a living donor liver donation. It aims to find out which scan is better at planning the surgery.
Rotterdam, South HollandAges 18–60 - NCT06774144Enrolling by invitationPhase 3
Rezafungin to prevent fungal infections in liver transplant patients
This trial tests whether a medicine called rezafungin can help prevent serious fungal infections in people who have received a liver transplant. If you have certain risk factors, this study may offer extra protection against infections.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05082077Enrolling by invitation
Liver transplant donor data registry for better organ preservation
This study builds a global registry that tracks how donor livers are matched and preserved for transplant. It may help improve how doctors keep donor livers viable before surgery by learning from real-world cases.
Birmingham, AlabamaAges 18 years+ - NCT06075745RecruitingPhase 2
CMV Vaccine Study for Liver Transplant Candidates
This trial tests a vaccine to prevent cytomegalovirus (CMV) infection in people awaiting a first liver transplant. You may be eligible if you have never been infected with CMV and are scheduled to receive a liver transplant within the next 1 to 12 months.
Birmingham, AlabamaAges 18 years+ - NCT06777719RecruitingPhase 1
A study of immune cells to prevent kidney rejection
This trial tests if giving you back specially grown immune cells (called Tregs) made from your own blood can help your body accept a new kidney from a living donor with less rejection. It is for people who are ready for a first kidney transplant.
NantesAges 18–99 - NCT06832189RecruitingPhase 1
Testing everolimus and epoetin for liver transplant tolerance
This trial is testing whether a combination of two drugs, everolimus and epoetin, can help liver transplant recipients gradually reduce their anti-rejection medicines. If successful, it may lead to long-term transplant tolerance with fewer side effects.
San Francisco, CaliforniaAges 18 years+ - NCT01644903Recruiting
Checking biomarkers after a liver transplant
This study follows people who are getting a liver transplant (including repeat transplants) to monitor changes in their body using test results. It may help doctors understand how patients are doing after transplant and improve care over time.
Chicago, IllinoisAges 18 years+ - NCT03707262RecruitingPhase 1/Phase 2
Brother or sister donor transplant using kidney and stem cells
This study tests a combined approach for kidney transplant patients: standard living-donor kidney transplant plus an added “stem cell” component taken from the same sibling donor. It aims to improve transplant outcomes by trying to better control the immune response and reduce complications.
Los Angeles, CaliforniaAges 18 years+ - NCT05106322Recruiting
Using a hand scanner to check fat buildup in liver grafts
This study tests whether an on-site, hand-held scanner during surgery can estimate fat-related liver changes in donated liver tissue. It may help surgeons better assess the quality of liver grafts while the transplant is happening.
VillejuifAges 18 years+ - NCT07576920Recruiting
Understanding Anxiety in Living Liver Donors
This study looks at anxiety levels in people who donate part of their liver to help someone else. Researchers want to understand how donors feel before and after surgery, which may help support donors better in the future.
MalatyaAges 18–65 - NCT03803423Recruiting
Using social media to find kidney or liver donors
This study tests a way to spread information on how to register as a live organ donor using social media. You may be contacted to help identify potential live kidney or liver donors, if you fit the study’s basic requirements.
San Diego, CaliforniaAges 18 years+ - NCT04195503Enrolling by invitation
Liver transplant for stable advanced bile duct cancer
This trial looks at liver transplant for people with advanced intrahepatic cholangiocarcinoma (a bile duct cancer inside the liver) when the cancer is not safely removable and stays controlled. It may help some patients live longer and with better quality of life by replacing the diseased liver—if strict safety and disease-stability requirements are met.
Toronto, OntarioAges 18 years+ - NCT05089604RecruitingPhase 4
Compare two tacrolimus forms to reduce tremors after liver transplant
This study compares immediate-release versus extended-release tacrolimus (an anti-rejection medicine) to see if one form causes fewer tremors after a first liver transplant. It may help you and your care team choose the best form if tremors are a problem while your body adjusts after transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT07651748Enrolling by invitationPhase 1/Phase 2
Testing Secretin to Improve Donated Liver Quality
This trial tests whether adding a hormone called secretin to a machine that preserves donated livers outside the body can improve liver quality and transplant outcomes. You may qualify if you're an adult receiving a standard deceased-donor liver transplant that needs special preservation techniques.
Rotterdam, South HollandAges 18 years+ - NCT06455280RecruitingPhase 1
A study of Siplizumab for autoimmune liver disease patients awaiting transplant
This trial tests a drug called Siplizumab in people with autoimmune hepatitis or primary sclerosing cholangitis who are on the liver transplant waitlist. It aims to see if the drug can help manage their condition before and after transplant.
New York, New YorkAges 18 years+ - NCT02081755Enrolling by invitationPhase 4
Everolimus after liver transplant to lower liver cancer return
This trial studies whether everolimus, a transplant medicine, can safely reduce the chance that liver cancer comes back after liver transplant. It compares how well the treatment works while carefully monitoring side effects and safety.
San Francisco, CaliforniaAges 18 years+ - NCT04201210RecruitingPhase 2
Stem cell transplant study for young people with severe sickle cell
This Phase 2 study tests a type of stem cell transplant that uses donor immune cells that have been specially “tweaked” to help treat sickle cell disease. It may help prevent serious sickle cell complications, but it requires careful matching and screening of organs and pregnancy status.
ViennaAges 2–35 - NCT07480057Recruiting
Bone health changes after liver transplant
This study tracks how liver transplantation affects your bone density and mineral metabolism. It aims to find changes early, which can help prevent fractures later.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT06353126RecruitingPhase 4
Chemoembolization before liver transplant for liver cancer
This trial tests whether using chemotherapy beads delivered directly to the liver (DEB-TACE) before a living donor liver transplant improves outcomes for people with liver cancer. If you have a tumor in the right side of the liver that fits certain size and number limits, and you are already scheduled for a transplant, this study may be an option.
ShanghaiAges 18–75 - NCT07578441Enrolling by invitation
VitaSmart HOPE System liver transplant registry
This study follows people who receive a liver transplant using a special machine called the VitaSmart HOPE System, which keeps the donated liver healthy before transplant. The study tracks how well these livers work after transplant.
Cleveland, OhioAges Any age - NCT07549503RecruitingPhase 2
Liver Transplant Immune Changes Study
This research study tracks early signs of immune system changes in children who received a liver transplant 3–7 years ago and are doing well. By studying blood and liver samples, researchers hope to better understand how to prevent rejection and improve long-term transplant survival.
San Francisco, CaliforniaAges 3–13 - NCT03627013RecruitingPhase 3
Compare two transplant fluid solutions for kidney, liver, pancreas
This Phase 3 study compares two types of transplant fluid (Custodiol-N vs Custodiol) to protect organs while they are stored before surgery. It may help by reducing damage to the kidney, liver, or pancreas during transplant preparation.
GrazAges 18 years+ - NCT07315204Recruiting
Liver viability test during machine perfusion
This trial tests a new way to check if a donated liver is healthy while it is kept on a machine that keeps it alive before transplant. Doctors measure a substance called FMN in the fluid that flows through the liver and in bile. This could help them know how well the liver might work after transplant.
Cleveland, OhioAges 18 years+
Hear when a new Living Donor Liver Transplantation trial opens
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Common questions
- Are there clinical trials for living donor liver transplantation?
- Yes. Clin2 currently lists 51 recruiting living donor liver transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a living donor liver transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a living donor liver transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.