Clinical trials
Low Back Pain clinical trials
Below are recruiting low back pain clinical trials, each written for real people, not researchers. We’re tracking 345 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06702189Recruiting
EXOPULSE Mollii Suit for low back pain
This trial tests a special suit (EXOPULSE Mollii) to see if it helps relieve low back pain. It may be an option if you've had back pain for at least 3 months and are not planning surgery.
Créteil, VAL DE MarneAges 18–75 - NCT06684665Enrolling by invitation
How emotions and social factors affect low back pain
This study looks at how social, psychological, and emotional factors might cause problems with movement and daily life in people with back pain. It could help doctors better understand and treat your pain.
Wenzhou, ZhejiangAges 18–75 - NCT06661850Recruiting
New imaging test to guide lower back surgery decisions
This study tests a new imaging tool called Nociscan to see if it helps doctors decide who will benefit from lumbar spine surgery for low back pain. It may help predict surgical outcomes and guide treatment.
Phoenix, ArizonaAges 18–70 - NCT05780021Recruiting
Support program for long-term low back pain after rehab
This trial tests whether a structured motivational support program can help people with long-term low back pain after they finish a rehab program. It may help you stay motivated and improve your day-to-day progress after treatment.
ParisAges 18 years+ - NCT06620133Recruiting
Pain education and goal setting for chronic low back pain
This trial tests whether learning about pain and setting your own exercise goals helps people with long-term low back pain become more active. You will receive online sessions and support to safely increase your physical activity.
Sydney, New South WalesAges 18 years+ - NCT05540548Recruiting
Podiatry assessment for balance and pain in chronic back pain
This study looks at whether a foot and posture specialist can help measure how balance relates to the pain you feel in chronic low back pain. It may help doctors better understand what to focus on for pain that lasts for months.
ValenciennesAges 18 years+ - NCT06611397Recruiting
Discogen study for lower back pain with leg pain
This trial tests a treatment called Discogen for people with lower back pain that also causes leg pain. It aims to see if the treatment helps reduce pain and improve function.
New York, New YorkAges 21–75 - NCT06590116Recruiting
Spinal manipulation for chronic low back pain
This study looks at how people feel about spinal manipulation therapy for long-term low back pain. It's for adults who have had pain in their lower back for more than three months and want to share their views on this type of treatment.
Gainesville, FloridaAges 18–70 - NCT06568198RecruitingPhase 2
Brain stimulation study for chronic low back pain
This trial tests whether a noninvasive brain stimulation technique called tACS can help reduce chronic low back pain. Participants will have brain scans and receive the treatment over several sessions.
Charlestown, MassachusettsAges 18–60 - NCT05452876RecruitingPhase 2
Back care program for adults with certain spine problems
This study tests a back-care pathway (a structured plan for care) for adults with specific spine-related conditions. It aims to see whether this approach improves care for people in Alberta who may benefit from organized back treatment and guidance.
Edmonton, AlbertaAges 18 years+ - NCT06517342Recruiting
Using a health app for low back pain
This study looks at what helps or stops people with chronic low back pain from using a smartphone app to become more active. It aims to find ways to make it easier for you to stay active.
Clermont-FerrandAges 18 years+ - NCT03707288Recruiting
Exercise study for neck and low back pain in medical students
This study looks at neck and low back pain in medical students and asks participants to follow a set exercise plan for a period of time. It may help researchers understand what kind of exercise support could improve symptoms in students.
Kingston, KingstonAges Any age - NCT06471920Recruiting
Telerehab for chronic low back pain in rural areas
This study tests whether a video-based physical therapy program can help people with chronic low back pain who live in rural areas. If you qualify, you'll get telerehabilitation (rehab done at home through video calls) to reduce pain and improve function.
Baltimore, MarylandAges 18 years+ - NCT06446596Recruiting
Phone-based exercise coach vs. standard home exercises for low back pain
This study compares doing exercises at home with a video coach on your phone versus doing standard exercises you get from a doctor. The goal is to see if the video program helps people with low back pain more than regular home exercises.
Valencia, Select OneAges 18–65 - NCT06454669RecruitingPhase 2
Dronabinol added to opioids for chronic low back pain
This trial tests whether adding dronabinol (a prescription medication derived from cannabis) to your current opioid pain treatment can help reduce chronic low back pain more effectively. It is for people who have had persistent low back pain for at least 3 months and are already on a stable opioid regimen.
Houston, TexasAges 18–64 - NCT06419439RecruitingPhase 2
Ketamine for Veterans with Chronic Back Pain and Depression
This study tests whether ketamine, combined with talk therapy, can help veterans with both chronic low back pain and depression. The goal is to reduce pain and improve mood.
Ann Arbor, MichiganAges 18 years+ - NCT06384001Recruiting
Meditation for chronic low back pain in older adults
This trial tests whether a meditation program can help reduce chronic low back pain in adults aged 50 and older. You'll learn meditation techniques that you can do at home using an internet connection, and the study will track how your pain changes over time.
Tallahassee, FloridaAges 50–89 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT06355414RecruitingPhase 1
Psilocybin for chronic back pain and depression
This trial tests if psilocybin, a psychedelic drug, can help people with long-term low back pain who also have depression. If you qualify, you'll receive psilocybin in a controlled setting, and researchers will see how it affects your pain and mood.
Baltimore, MarylandAges 21–80 - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT05840302Recruiting
Pain education program to increase activity in chronic low back pain
This trial studies whether teaching “pain neuroscience” (how pain works in the body and brain) helps people with long-term low back pain move more. It compares an education program as part of a multidisciplinary rehab to usual care during your planned hospital stay.
Lamalou-les-BainsAges 18 years+ - NCT04658628Recruiting
Brain scan study to learn who responds to spinal cord stimulation
This trial uses brain imaging to understand which people with long-lasting low back pain are more likely to benefit from spinal cord stimulation (SCS). If you’re being considered for an SCS trial, the scans may help researchers predict response and improve future care.
Los Angeles, CaliforniaAges 21 years+ - NCT06208514Recruiting
Brief Pain Exposure Therapy for chronic pain conditions
This study tests a type of talk therapy called Brief Pain Exposure Therapy (BPET) for people with certain chronic pain conditions like fibromyalgia, lupus, or chronic low back pain. It aims to help reduce pain by changing how your brain responds to it.
Ann Arbor, MichiganAges 18 years+ - NCT06106191Recruiting
Mindfulness program for chronic low back pain
This trial tests a mindfulness-based program designed to help people with long-term low back pain. It aims to see if combining mindfulness with a personalized approach can improve pain management and daily functioning.
Boston, MassachusettsAges 18 years+
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Common questions
- Are there clinical trials for low back pain?
- Yes. Clin2 currently lists 345 recruiting low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.