Clinical trials
Lower Extremity clinical trials
Below are recruiting lower extremity clinical trials, each written for real people, not researchers. We’re tracking 123 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03663790Recruiting
Gait retraining for knee osteoarthritis movement patterns
This trial tests whether a structured walking retraining program can improve how your leg moves if you have knee osteoarthritis. It may help reduce strain on your lower body during walking by changing walking technique.
Manassas, VirginiaAges 18–80 - NCT06223217Recruiting
New quality-of-life survey for leg artery disease patients
This study tests a new questionnaire (modified VascuQol) to measure how leg artery disease affects your daily life. It aims to create a better tool for doctors to track your symptoms and well-being.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06156904Recruiting
Study of b.Bone bone graft for defects in arms, legs, pelvis
This trial is following patients who receive a bone graft using a product called b.Bone to treat bone defects in the arms, legs, or pelvis. Researchers will collect information during your regular follow-up visits to see how well the bone heals.
BerlinAges 18 years+ - NCT07834333Recruiting
Brain stimulation to help arm and leg recovery after stroke
This trial tests a non-invasive brain stimulation technique called theta burst stimulation to see if it can improve arm and leg function in people who recently had a stroke. It may help with movement recovery in the first few months after stroke.
Ankara, YenimahalleAges 45 years+ - NCT06428032Recruiting
Habit training for children with bilateral cerebral palsy
This trial tests a therapy called HABIT-ILE to see if it helps children with bilateral cerebral palsy improve hand use and brain function. It may be a good fit if your child can follow instructions and has certain levels of hand and movement ability.
Santiago, Santiago MetropolitanAges 8–18 - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT07754110Recruiting
A therapy for balance and coordination after stroke
This study tests a therapy called HABIT-ILE to see if it helps improve balance and coordination in people who have had a stroke. If you have had a stroke affecting one side of your body, this might help you move better.
Mansehra, KpkAges 40–60 - NCT07685730Recruiting
Comparing blood pressure readings in arm vs leg during C-section
This study compares blood pressure measurements taken from the arm versus the leg during planned Cesarean sections using a special monitor. It aims to see which location gives more accurate readings for women having spinal anesthesia.
Columbus, OhioAges 18 years+ - NCT07686809Recruiting
Leg therapy for children with one-sided weakness
This study tests a new leg exercise program to help children with hemiplegia walk better. The therapy may improve balance and movement in the affected leg.
CairoAges 6–8 - NCT06673823Recruiting
Mirror therapy for leg movement in children with CP
This study tests whether mirror therapy—where your child watches the reflection of their good leg moving—can help improve movement in their affected leg. It is designed for children with cerebral palsy who have mild to moderate leg stiffness.
Lahore, Punjab ProvinceAges 6–12 - NCT06274697Recruiting
Testing a magnetic sensor for artery blood flow
This study tests a new magnetic sensor that measures blood flow in your arteries, comparing it to the standard method. It takes place in the heart-lung unit at Montpellier University Hospital, and aims to see if the sensor is accurate for people with or without leg artery disease.
MontpellierAges 18 years+ - NCT07613333Recruiting
Exercise Program for New Mothers
This study tests an exercise program designed for women who have given birth within the past 2 years. Researchers want to learn how exercise affects energy levels and overall health after pregnancy.
Waukesha, WisconsinAges 18 years+ - NCT07613931RecruitingEarly Phase 1
New Compression Device for Leg Lymphedema Treatment
This study tests a newer version of a pneumatic compression device (a machine that gently squeezes your leg to reduce swelling) for lymphedema—persistent swelling in the lower leg or foot. Researchers want to see if the updated compression settings work better to reduce swelling and improve how your leg feels and functions.
Houston, TexasAges 18 years+ - NCT07592871Recruiting
Knee Injury and Arthritis Long-Term Health Study
This study follows patients with knee injuries or wear-and-tear arthritis over time to understand how these conditions develop and change. Your health information helps doctors learn what treatments work best and how to prevent problems.
Ningbo, ZhejiangAges 18–90 - NCT07570277Recruiting
Nursing Support for Leg Vein Surgery Recovery
This study tests whether specialized nursing guidance helps patients recover better after surgery for varicose veins (enlarged veins in the legs). The nursing support focuses on helping you manage your own care at home after surgery.
Nanchang, Jang XIAges 18 years+ - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06105788Recruiting
Exercise and pain relief for knee arthritis
This study looks at how moving your arms and legs might help reduce pain for people with knee osteoarthritis. If you join, you will do some light exercise so researchers can see if it helps your knee feel better.
El Paso, TexasAges 45–90 - NCT07558174Recruiting
Monitoring blood flow during leg artery surgery with imaging
This study tests a special imaging camera that measures blood flow in your leg before, during, and after surgery to improve the artery. The goal is to help doctors see in real time whether the surgery is working properly.
Leiden, South HollandAges 18 years+ - NCT07550348Recruiting
Pain Relief Comparison for Lower Leg Surgery Nerve Block
This study compares two common numbing medications used together versus one alone for nerve-blocking surgery on the lower leg. Researchers want to see which approach works better and lasts longer for pain relief after your procedure.
ErzurumAges 18–65 - NCT06098157Recruiting
Non-healed broken bones in arm or leg after surgery
This is a registry study that collects information from people who have had surgery for a broken arm or leg bone that did not heal on its own. It helps doctors better understand why some bones don't heal and how to improve treatment.
Tübingen, Baden-WurttembergAges 18 years+ - NCT07488338Recruiting
Movement and hand training for children with SMA
This study tests whether a combined program of home-based activities and hand training can help children with spinal muscular atrophy improve their movement and daily function. It is for children who can sit or walk with support and have been on stable medication for at least 6 months.
New York, New YorkAges 5–17 - NCT07488429Recruiting
Brain stimulation plus therapy for leg function in cerebral palsy
This study tests whether combining a gentle brain stimulation treatment (rTMS) with physical therapy can help improve leg movement and reduce muscle stiffness in children with cerebral palsy. The goal is to see if this combination works better than therapy alone.
AnkaraAges 5–18 - NCT06343688Recruiting
How ankle braces affect motor skills in CP
This study tests how wearing special ankle braces (called DAFOs) right away affects movement and balance in children with spastic diplegic cerebral palsy. It aims to see if the braces make it easier to walk and stand.
BoluAges 4–15 - NCT07387653Recruiting
Leg circulation monitoring during pelvic surgery
This trial tests a new way to check blood flow and oxygen levels in your legs during pelvic surgery when you're in the lithotomy (legs-up) position. It aims to catch any circulation problems early, which could help prevent leg injuries.
Houston, TexasAges Any age
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Common questions
- Are there clinical trials for lower extremity?
- Yes. Clin2 currently lists 123 recruiting lower extremity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lower extremity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lower extremity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.