Clinical trials
Lumbar Spine Surgery clinical trials
Below are recruiting lumbar spine surgery clinical trials, each written for real people, not researchers. We’re tracking 86 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06367855RecruitingPhase 4
Dexamethasone before spine surgery for pain control
This study tests whether giving a single dose of the steroid dexamethasone before minimally invasive spine surgery can help reduce pain and inflammation afterward. It is for people aged 50–80 who are having surgery on 1 or 2 levels of their lower back and have not had spine surgery before.
Pathum Thani, Changwat Pathum ThaniAges 50–80 - NCT07461636Recruiting
Robotic-assisted screw placement in spine surgery
This trial studies how well a robotic system helps surgeons place screws in the spine. It may help make the surgery more precise and safer.
GothenburgAges Any age - NCT07348523Recruiting
Comparing two types of back pain blocks after lumbar spine surgery
This trial compares two ways of delivering a pain-blocking injection (erector spinae plane block) after a single-level lower back surgery. The goal is to see which approach provides better pain relief after surgery.
SamsunAges 18–70 - NCT07681648Enrolling by invitationPhase 4
Nerve blocks vs local numbing for lumbar spine surgery
This study compares two types of nerve blocks (a longissimus plane block and a multifidus plane block) to a local numbing injection for pain control during lumbar spine surgery. It aims to find which method works best for patients having back surgery.
Aswān, Aswan GovernorateAges 18–65 - NCT06709391Recruiting
Spinal fusion vs. no surgery for chronic low back pain
This trial tests whether a spinal fusion surgery is better than staying with non-surgical treatments for people with long-term, severe low back pain from worn-out discs in the lower spine. It aims to find out which approach offers better pain relief and quality of life.
GothenburgAges 25–65 - NCT07173413Recruiting
Quality of phone check-ins after spine surgery
This study checks how well telephone follow-ups work for patients who had lower back surgery at a Danish hospital. It may help improve future care.
Aalborg, AalborgAges 18 years+ - NCT05701046Recruiting
Front vs back surgery for a slipped lower-back vertebra
This trial compares two surgical approaches—operating from the front/side versus from the back—for a specific type of lower-back slip called lumbar isthmic spondylolisthesis. You may be eligible if you need surgery at a single level and have not had prior spine surgery, and if your back condition matches their exact limits.
Vancouver, British ColumbiaAges 18 years+ - NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs
This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.
Beverly Hills, CaliforniaAges 50 years+ - NCT07222072RecruitingPhase 4
Methadone to reduce opioid use after spine surgery
This study tests whether giving methadone during and after major spine surgery can help reduce the need for other opioid pain medicines later. It is for adults having multilevel fusion in the lower or mid-back.
Cleveland, OhioAges 18–72 - NCT06971835Enrolling by invitation
NanoParticle Matrix spine surgery registry
This study follows people who receive a special bone graft material called NanoParticle Matrix (NPM) during spine surgery. Researchers want to track outcomes over two years to see how well it works.
Baton Rouge, LouisianaAges 18 years+ - NCT07737912Enrolling by invitation
SpinePal app for spine fusion recovery
This study tests a smartphone app called SpinePal along with a wrist fitness tracker to help you recover after spine fusion surgery. If you qualify, you'll use the app and tracker for a few months to see if they improve your recovery and reduce pain.
Lebanon, New HampshireAges 18 years+ - NCT07844577Recruiting
Zero Echo Time MRI for spinal bone assessment
This trial tests whether a new MRI technique, called zero echo time (ZTE), can replace some CT scans for diagnosing spinal bone problems. If successful, you may not need a CT scan, which exposes you to radiation, and instead get all the needed information from this MRI scan.
BrusselsAges 18 years+ - NCT07325812Recruiting
Lung opening maneuvers during spine surgery
This study tests whether periodic lung opening maneuvers during back surgery can reduce lung collapse and improve breathing mechanics. Doctors will use ultrasound to monitor your lungs.
IstanbulAges 18–65 - NCT07174349RecruitingPhase 4
Medication to prevent urine retention after spine surgery
This trial tests whether a medication called tamsulosin can prevent or shorten the time you need a urinary catheter after spine surgery. It is for people having specific types of neck or lower back surgery.
Rochester, MinnesotaAges 35 years+ - NCT07047300Recruiting
How a heel lift insole affects walking for healthy adults
This study tests whether wearing a heel lift insole changes how your legs and lower back move while walking. It may help understand if such insoles can benefit people with certain conditions, but right now it only includes healthy volunteers.
Giza, Giza GovernorateAges 18–25 - NCT06990893Recruiting
Oliceridine vs morphine for pain after lumbar surgery
This study compares a new pain medicine called oliceridine with morphine or sufentanil to see which works better after lumbar spine surgery. It aims to find a safer and more effective way to manage pain after your operation.
Anqing, AnhuiAges 18–65 - NCT02314988RecruitingPhase 2/Phase 3
Tranexamic acid to reduce bleeding in spine surgery
This trial tests whether tranexamic acid (a medicine that helps blood clot) can reduce blood loss during long spine surgery after an injury. It may help lower the chance of needing transfusions and manage surgical bleeding.
San Francisco, CaliforniaAges 18–80 - NCT07834931Recruiting
Spine implant for low back pain from disc degeneration
This study tests an implant placed in the lower spine to treat back pain caused by disc degeneration. It aims to see if the implant helps reduce pain and improve function in people who have not improved with other treatments.
Madrid, MadridAges Any age - NCT07834736Recruiting
Titanium implant for lower back disc pain
This study tests a new titanium implant to help stabilize the lower spine in people with painful, worn-out discs. It aims to see if the implant works well and is safe in everyday practice.
Madrid, MadridAges Any age - NCT07480278Recruiting
Pain relief after back surgery: two injections compared
This trial tests two different injection methods to see which one provides better pain relief after lower back surgery. If you are having a microdiscectomy, this study may help determine the best way to manage your post-operative pain.
Bursa, NilüferAges 18–65 - NCT07354581Recruiting
Pain blocks after lower back surgery
This trial compares two types of pain-block injections (erector spinae plane block versus quadro-iliac plane block) given during lower back surgery to see which controls pain better. It may help you have less pain and need fewer pain medicines after your operation.
BursaAges 18–65 - NCT07354412Enrolling by invitation
Can cannabis affect anesthesia and inflammation in spine surgery?
This study looks at how using cannabis before or during lumbar spine surgery might affect anesthesia and inflammation. It compares patients who have used cannabis to those who have not, to see if there are differences in pain, recovery, or side effects.
Columbia, MissouriAges 18 years+ - NCT07348419Recruiting
Pain blocks after single-level lumbar disc surgery
This study compares two types of pain-blocking injections (Quadro-Iliac vs Thoracolumbar Interfascial Plane Block) to see which provides better pain relief after a single-level lumbar disc surgery. If you are having this surgery, the trial may help you have less pain and use fewer pain medicines afterwards.
SamsunAges 18–70 - NCT07020000Recruiting
Lumbar fusion with EARP nerve cuff electrode
This trial uses a medical device called the EARP Interbody System with a nerve cuff electrode during lower back fusion surgery. It collects real-world data to confirm the device is safe and works well for people having fusion between the second and fifth lumbar vertebrae.
Jacksonville, FloridaAges 22–80
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Common questions
- Are there clinical trials for lumbar spine surgery?
- Yes. Clin2 currently lists 86 recruiting lumbar spine surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lumbar spine surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lumbar spine surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.