Clinical trials
Spine Surgery clinical trials
Below are recruiting spine surgery clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06975072RecruitingPhase 4
Can magnesium affect nerve monitoring during back surgery?
This study tests if giving magnesium during open thoracolumbar fusion surgery (a type of back surgery) affects nerve monitoring. It might help find the right dose for patients while keeping their nerves safe.
San Francisco, CaliforniaAges 18 years+ - NCT06827795Recruiting
Testing a new surgical tool for spine surgery
This study compares a new surgical tool, the Surgify Halo, to a standard tool used in spine surgery. It aims to see which is easier to use and performs better for removing bone during spine surgery.
New York, New YorkAges 21–85 - NCT07720856Recruiting
Recovery pillow for spine surgery patients
This study tests a special recovery pillow designed to help you heal more comfortably after lower back fusion surgery. If you join, you will use the pillow after your operation to see if it improves your recovery.
The Bronx, New YorkAges 19 years+ - NCT04312880Enrolling by invitationPhase 4
Tranexamic acid during elective back surgery to reduce bleeding
This trial studies whether giving tranexamic acid (a medicine that helps reduce bleeding) during planned lower-back decompression surgery can lower blood loss or related complications. It compares patients who receive the infusion during surgery to those who meet study procedures and safety requirements.
Albany, New YorkAges 18–80 - NCT07061067Recruiting
How symptom duration affects lower back surgery results
This study looks at how long your symptoms have lasted before lower back surgery and whether that affects your recovery. If you're planning a lumbar spine operation and have symptoms like back or leg pain, this trial may help doctors understand the best timing for surgery.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT06808022Enrolling by invitation
Back exercises before spine surgery
This trial studies whether doing back exercises before spine surgery helps improve recovery. If you are having spine surgery and can safely do physical therapy, you may be able to join.
La Jolla, CaliforniaAges 18 years+ - NCT07365800Enrolling by invitationPhase 4
Combination pain control after complex spine surgery
This study tests a combination of three medications (methadone, dexmedetomidine, and ketamine) to control pain after major spine surgery. If you are having complex spine surgery, this trial may offer better pain relief without needing as much opioid medication.
Columbia, MissouriAges 18–79 - NCT06288256Recruiting
Spine surgery study: genes, thinking, and pain
This study is for people getting planned spine surgery. It looks at how your genes and thinking skills might affect your pain and use of pain medicine after surgery.
New York, New YorkAges 18 years+ - NCT06083298Recruiting
Nerve blocks for pain after cervical spine surgery
This trial tests two types of nerve blocks to see which works better for pain after back-of-the-neck surgery. It aims to help patients have less pain and use less opioid medicine.
Zagazig, AlsharqiaAges 21–60 - NCT07455565Recruiting
Pain monitoring with ANI after lumbar spine surgery
This study tests a new way to monitor pain after lower back surgery using a device called ANI, which tracks your body's response to pain. The goal is to see if this method helps doctors give you better pain relief.
Antalya, AntalyaAges 18–65 - NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT07344467Recruiting
Melatonin vs. Pregabalin for pain and anxiety after spine surgery
This trial compares two medications—melatonin and pregabalin—to see which works better at reducing pain and anxiety after spine surgery. It aims to find a safer, effective option for recovery.
Tanta, El-GharbiaAges 21–60 - NCT07506720Recruiting
Early biking in bed after spine surgery
This study tests whether a short session of pedaling a special bike while lying in bed, soon after spine surgery, can help you recover faster. It's for people who could walk before surgery and are stable after the operation.
Montreal, QuebecAges 18 years+ - NCT06458309Recruiting
Managing spine fractures in adults
This study tests a way to manage fractures in the mid-to-lower back (thoracic and lumbar spine) for adults. It looks at how well the current treatment works for these types of spine injuries.
SohagAges 16–70 - NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery
This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.
Tanta, El-GharbiaAges 21–60 - NCT07396077Recruiting
Pre-op health boost for elderly spine surgery patients
This trial tests if a 6-week prehabilitation program (exercise and nutrition) before spine surgery helps elderly patients recover better. It is for people 75 or older with long-term lower back problems who need spinal fusion surgery.
Beijing, Beijing MunicipalityAges 75 years+ - NCT04825522RecruitingPhase 4
Vancomycin powder during spine surgery to prevent infection
This trial studies whether placing antibiotic powder (vancomycin) directly in the surgical wound during spine surgery can lower the chance of infection. It may help patients by reducing wound infections after surgery, but it also depends on your surgery details and follow-up timeline.
Windsor, OntarioAges 18 years+ - NCT07017985Recruiting
Diabetes in patients having first lower back surgery
This study looks at how common diabetes is in people about to have their first lower back surgery (lumbar spine surgery). It aims to help doctors better understand the link between diabetes and spine health.
MassyAges 18 years+ - NCT05817747Recruiting
Using big data to predict outcomes after spine surgery
This study collects information from people having surgery for problems in the lower (lumbar) or neck (cervical) spine. It tests whether using “big data” from routine care can help predict surgical outcomes and improve future decisions.
Ängelholm, Skåne CountyAges 18 years+ - NCT05332249Recruiting
Registry for Degenerative Spine Disease in the Neck and Low Back
This study is a registry (a way to collect health information) for people with wear-and-tear (“degenerative”) problems in the neck and/or low back. It may help doctors better understand these conditions and improve future care plans.
Seoul, KoreaAges 18–100 - NCT07549165Recruiting
How the IVC changes during back stabilization surgery
This study measures a large vein in your belly (the IVC) during planned lumbar spine stabilization surgery to understand how it responds to the surgery. The goal is to improve how doctors monitor your blood circulation during the operation.
TrabzonAges 18 years+ - NCT05895968Recruiting
Barbed Suture for Obese Patients Having Neck Surgery
This trial tests a special type of stitch (called barb suture) used during back-of-neck surgery. It is for people who are obese and need surgery for cervical spinal problems, to see if it helps recovery.
Xi'an, Shannxi ProvinceAges 28–85 - NCT05996133RecruitingPhase 4
Neck Numbing Shot vs. Sham for Neck Surgery Pain
This trial tests whether a numbing injection (called a multifidus cervicis plane block) in the neck muscles helps reduce pain after back-of-the-neck fusion surgery. Half the participants will get the real block, the other half a sham (fake) block, to see if it really works.
Hartford, ConnecticutAges 40–80
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Common questions
- Are there clinical trials for spine surgery?
- Yes. Clin2 currently lists 91 recruiting spine surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a spine surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a spine surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.