Clinical trials
Lymph Node Disease clinical trials
Below are recruiting lymph node disease clinical trials, each written for real people, not researchers. We’re tracking 177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03779009Recruiting
Study mapping sentinel lymph nodes to guide colon cancer surgery
This trial looks at a minimally invasive surgery approach for people with colon adenocarcinoma that has not spread to lymph nodes or other organs. The team will use special mapping tests on the sentinel lymph node to better understand the cancer spread and help guide treatment decisions.
GhentAges 18 years+ - NCT04109079Recruiting
Best surgery plan for breast cancer lymph nodes after chemotherapy
This study looks at the safest and most useful way to remove and check breast-cancer lymph nodes in the armpit after you finish chemotherapy given before surgery. It may help you avoid unnecessary surgery while still getting accurate information about how well the treatment worked.
DublinAges 18 years+ - NCT05981014RecruitingPhase 1/Phase 2
Immune cells from lymph nodes for HER2-negative breast cancer
This trial tests whether taking immune cells from your lymph nodes and giving them back to you can help shrink breast cancer that has not responded fully to initial chemotherapy. It is for women with HER2-negative breast cancer who have had stable disease after two cycles of a standard chemotherapy combination.
Guangzhou, GuangdongAges 18–70 - NCT06121570RecruitingPhase 1
Study of immune cells from lymph nodes for HER2-negative breast cancer
This trial tests whether using a patient's own immune cells from lymph nodes near the tumor, given as a treatment before surgery, can help shrink HER2-negative breast cancer. It is for people whose cancer has not responded fully to two cycles of initial chemotherapy.
Guangzhou, GuangdongAges 18–70 - NCT06831032Recruiting
Adaptive radiation for prostate cancer in lymph nodes
This trial tests a type of targeted radiation (SBRT) for prostate cancer that has come back only in certain lymph nodes around the belly or hip. The goal is to see if adapting the radiation plan during treatment can make the response last longer.
Toronto, OntarioAges 18 years+ - NCT04671511Recruiting
Check targeted lymph node surgery for early breast cancer
This study tests a more focused surgery approach to remove lymph nodes in the armpit for people with early breast cancer that has been found in 1–2 axillary lymph nodes. It may help guide more precise treatment while checking how well this approach works.
Montreal, QuebecAges 18 years+ - NCT07328386Recruiting
Neck surgery for brain lymphatic disorder
This trial tests a neck surgery (lymphaticovenous and lymph node-to-vein anastomosis) to see if it improves symptoms in people with Alzheimer's disease linked to a brain lymphatic circulation disorder. It focuses on those with moderate-stage Alzheimer's and confirmed amyloid buildup.
SeoulAges 19–100 - NCT05838053Recruiting
Segmentectomy versus lobectomy for small lung cancer
This trial compares two types of lung surgery—removing a small lung segment versus removing an entire lung lobe—for small lung adenocarcinoma (≤ 2 cm). It may help you choose the safest approach that still controls the cancer.
Yangpu, Shanghai MunicipalityAges 20–79 - NCT06621823Recruiting
Robotic ultrasound to check lymph nodes during gynecologic cancer surgery
This trial tests a new robotic ultrasound tool to see if it can better find cancer in lymph nodes during surgery. It may help doctors decide exactly which nodes to remove, avoiding unnecessary surgery.
RomaAges 18–99 - NCT06965062Recruiting
Neck surgery for Alzheimer's: a first test
This study tests a new surgery called cervical lymphatic bypass to see if it can help people with Alzheimer's disease. The surgery creates a new connection in the neck to improve drainage of waste from the brain, which may slow memory loss.
SingaporeAges 50–80 - NCT07060378Recruiting
Contrast Dye for Better Lung Biopsy
This trial tests whether using a special contrast dye during an ultrasound-guided biopsy (EBUS) makes it easier to see and sample lung tumors or swollen lymph nodes. It may help doctors get more accurate tissue samples with fewer tries.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT06936514Enrolling by invitation
Lymphatic surgery for Alzheimer's: a clinical study
This trial tests a surgery that targets the lymphatic system in the neck to help people with moderate-to-severe Alzheimer's disease. The goal is to see if it can improve cognitive function.
TianjinAges 50–80 - NCT06001528Recruiting
Predicting lymph node spread in breast cancer
This study looks at whether substances called metabolites in your blood and breast tissue can help predict if breast cancer has spread to the first lymph node (sentinel node). If you are scheduled for breast cancer surgery and have not had prior treatment, the study team will use your blood and tissue samples to try to improve prediction.
Shantou, GuangdongAges 18 years+ - NCT07140172Recruiting
Radiation or surgery for node-positive breast cancer
This trial compares two treatments for people with breast cancer that has spread to the lymph nodes: radiation therapy to the armpit or surgery to remove the lymph nodes. The goal is to see which approach works best after a tailored surgery to remove the most suspicious lymph nodes.
Bethesda, MarylandAges 18 years+ - NCT06278454RecruitingPhase 1
Radioactive injection for advanced pancreatic cancer
This trial tests a new radioactive injection called NRT6008 for people with pancreatic cancer that cannot be surgically removed. It aims to see if the treatment can shrink the tumor and improve survival.
Zhengzhou, HenanAges 18–80 - NCT07338721Recruiting
Ultrasound vs. incision for finding sentinel lymph nodes in breast cancer
This trial compares two techniques for finding the first lymph node that breast cancer might spread to (the sentinel node). It tests if using ultrasound guidance through a small axillary incision is better than the standard method.
AntalyaAges 18 years+ - NCT06883084Enrolling by invitation
How lymph node changes affect rectal cancer outcomes
This trial looks at how much the lymph nodes respond to chemoradiation before surgery in people with locally advanced rectal cancer. It aims to understand if that response can predict long-term results and guide future treatment choices.
Ages 18–65 - NCT07304934Recruiting
New blood test model to check lymph node status in breast cancer
This study uses a blood test and imaging to predict whether breast cancer has spread to underarm lymph nodes, helping guide surgery. It may reduce unnecessary lymph node removal.
Hangzhou, ZhejiangAges 18 years+ - NCT04496479RecruitingPhase 2
Transplanting donor liver cells near lymph nodes in advanced liver disease
This Phase 2 study tests whether transplanting donor liver cells near lymph nodes can improve outcomes in people with advanced cirrhosis from certain liver conditions. It may help your liver function by adding healthy liver cells, but eligibility is tightly based on your current liver status and other health factors.
Boston, MassachusettsAges 18–70 - NCT06990737RecruitingPhase 2
Sentinel node biopsy for high-risk skin cancer of the head and neck
This trial is testing whether a procedure called sentinel lymph node biopsy (SLNB) can help manage high-risk skin cancer on the head and neck that has not spread to lymph nodes. It is for people whose skin cancer is considered high-risk due to features like size, depth, or location, and who are able to have surgery.
Sacramento, CaliforniaAges 18 years+ - NCT06065891Recruiting
Lymph node removal in pancreatic cancer surgery
This trial studies whether removing extra lymph nodes during surgery for pancreatic cancer can help find if the cancer has spread. It is for patients whose tumor is considered removable or borderline removable.
OdenseAges 18 years+ - NCT04555226Recruiting
Lymph node surgery for advanced cervical cancer
This trial studies whether removing lymph nodes during surgery helps people with stage IIICr cervical cancer. It looks at outcomes and may help guide better treatment for lymph node spread.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06262516Recruiting
Lymph node removal during kidney/ureter cancer surgery
This study looks at whether removing nearby lymph nodes during standard kidney/ureter removal surgery helps people with upper tract urothelial carcinoma. You will be placed into one of two groups – one gets the usual surgery alone, the other gets surgery plus lymph node removal.
Gainesville, FloridaAges 19 years+ - NCT06448897Recruiting
AI model to predict lymph node spread in cervical cancer
This study uses artificial intelligence to analyze your preoperative MRI and pathology results to better predict if cervical cancer has spread to pelvic lymph nodes. The goal is to improve future treatment decisions for patients with cervical cancer.
Shanghai, Shanghai MunicipalityAges 18–80
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Common questions
- Are there clinical trials for lymph node disease?
- Yes. Clin2 currently lists 177 recruiting lymph node disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymph node disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymph node disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.