Clinical trials
Lymph Node Disease clinical trials
Below are recruiting lymph node disease clinical trials, each written for real people, not researchers. We’re tracking 176 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05618821RecruitingPhase 2
Indocyanine green dye during stomach surgery for leftover cancer
This Phase 2 study tests whether using a special light-activated dye (indocyanine green) during laparoscopic stomach surgery can improve surgical outcomes for people with remnant (leftover) stomach cancer that has not spread to distant organs. It may help surgeons better find lymph nodes while operating.
Fuzhou, FujianAges 18–75 - NCT05695924Recruiting
Surgery to reduce arm swelling after breast cancer
This trial studies whether a specific surgery (a lymph vessel transplant) can reduce upper-arm lymphedema in people who developed swelling after breast cancer treatment. You must already have tried standard therapy and still have persistent, mild-to-moderate swelling.
Stanford, CaliforniaAges 18–75 - NCT05703126Recruiting
Blood vessel and heart strength tests in AML patients
This study looks at how well your blood vessels and heart pumping ability work in people with acute myeloid leukemia (AML) receiving certain chemotherapy. It may help doctors better understand heart risk during treatment and tailor monitoring to you.
Samara, Samara OblastAges 18–65 - NCT05899361Recruiting
Imaging protocol to map lymph nodes and urologic organs
This trial studies a new way to use medical scans to better find lymph nodes and nearby urologic organs before surgery. It may help surgeons plan operations for cancers or other conditions in the urologic area.
Boston, MassachusettsAges 18 years+ - NCT06091423RecruitingPhase 2
XELOX plus fruquintinib and sintilimab for stomach cancer with liver or lymph node spread
This trial tests a combination of chemotherapy (XELOX), a targeted therapy (fruquintinib), and an immunotherapy (sintilimab) to shrink stomach cancer that has spread only to the liver or retroperitoneal lymph nodes. The goal is to make the cancer removable by surgery.
NanjinAges 18–75 - NCT06104371Recruiting
Magnetic markers to find lymph nodes before chemo for breast cancer
This trial tests a new method using magnetic markers (Magtrace and Magseed) to find lymph nodes before chemotherapy. It may help doctors better target the lymph nodes that need to be removed during breast cancer surgery.
GothenburgAges 18–85 - NCT06161207RecruitingPhase 3
Laparoscopic surgery for stomach cancer using 3D and dye
This trial tests a new way to remove stomach cancer using 3D-4K cameras and a special dye during laparoscopic (keyhole) surgery. It may help surgeons see the cancer better and remove it more precisely.
Fuzhou, FujianAges 18–75 - NCT06197581Recruiting
Safety of Radiation with Modern Breast Cancer Drugs
This study checks if giving certain modern breast cancer drugs at the same time as radiation is safe. It's for women who need radiation and are also taking one of these drugs: capecitabine, a CDK4/6 inhibitor, a PARP inhibitor, immunotherapy, or a HER2 inhibitor.
Beijing, Beijing MunicipalityAges 18–70 - NCT06253715RecruitingPhase 3
Shorter TB treatment for children
This trial tests a shorter treatment for children with tuberculosis (TB) that is not drug-resistant. It aims to find out if a shorter regimen works as well as the standard longer one, making treatment easier for children and their families.
ChennaiAges birth–9 years - NCT06259513Recruiting
Skipping armpit surgery for breast cancer patients
This trial tests whether it's safe to skip armpit surgery in older women with small, low-risk breast cancers. If you qualify, you would have a mastectomy without removing lymph nodes from your armpit.
SingaporeAges 21–80 - NCT06309745Recruiting
Lowering treatment for Stage II testicular cancer
This trial tests lowering the intensity of treatment (de-escalation) for Stage II seminoma, a type of testicular cancer. You may receive either a surgery to remove lymph nodes or a single round of chemotherapy (carboplatin), instead of more aggressive standard treatments, to see if it's safe and effective.
LondonAges 16 years+ - NCT06321653Recruiting
Lymphedema after radiation for early breast cancer with 1-2 positive nodes
This trial aims to see if a shorter course of radiation after breast-conserving surgery affects arm swelling (lymphedema) in people with early breast cancer that has spread to 1 or 2 nearby lymph nodes. The goal is to learn if this approach is safe and effective.
MilanAges 18 years+ - NCT06341595RecruitingPhase 2
Chemo, radiation and immunotherapy before surgery for stomach cancer with PALM
This trial tests combining chemotherapy, radiation, and an immunotherapy drug (sintilimab) before surgery for advanced stomach cancer that has spread to lymph nodes near the aorta (called PALM). The goal is to see if this approach can shrink the tumor enough to allow complete removal.
Nanjing, JiangsuAges 18–75 - NCT06341621RecruitingPhase 3
Skipping chemo for ER+/HER2- breast cancer with 1–3 positive nodes
This trial tests whether skipping chemotherapy is safe for women with a specific type of early-stage breast cancer (ER-positive, HER2-negative) that has spread to 1–3 lymph nodes. Instead of chemo, you would receive a targeted pill called abemaciclib after standard hormone therapy.
ShanghaiAges 18–80 - NCT06354738Recruiting
Endometrial cancer study with genetic and surgical insights
This study looks at combining genetic testing with surgical exams to better understand endometrial cancer. It may help doctors see which treatments could work best for you.
LeuvenAges 18 years+ - NCT06540443RecruitingPhase 1
Enhanced MRI for staging head and neck cancer
This trial tests a new imaging agent (MPB-2043) that may help doctors see cancer spread to lymph nodes more clearly during an MRI scan. It is for people with head and neck cancer who are planning to have lymph node surgery.
TaipeiAges 20 years+ - NCT06593665RecruitingPhase 3
Morphine in spine vs. IV methadone for testicular cancer surgery pain
This trial compares two ways to manage pain after surgery for testicular cancer: a single injection of morphine into the spine (intrathecal morphine) vs. methadone given through an IV during surgery. The goal is to see which provides better pain relief and fewer side effects.
Indianapolis, IndianaAges 18–80 - NCT06444269RecruitingPhase 2
Precision radiation before surgery for early hormone-positive breast cancer
This trial tests a focused radiation treatment before surgery for early-stage breast cancer that is hormone receptor positive and HER2 negative. The goal is to give precise radiation only to the tumor, with the hope of reducing side effects and improving outcomes.
Dallas, TexasAges 18 years+ - NCT06610539Recruiting
Magnetic tracer for sentinel node biopsy in breast cancer
This study tests a magnetic tracer call Magtrace to help find and remove the first lymph node (sentinel node) during breast cancer surgery. The goal is to see if it works well for people having breast-conserving surgery.
Chapel Hill, North CarolinaAges 18 years+ - NCT06623266Recruiting
Observation vs. neck surgery for early mouth cancer
This study compares two approaches for early-stage mouth cancer: careful observation of the neck versus a preventive surgery to remove neck lymph nodes. The goal is to see which strategy works better to prevent cancer from spreading.
ShanghaiAges 18–75 - NCT06656949Recruiting
ICG injection for lymph node mapping in endometrial cancer
This trial tests whether injecting a dye called indocyanine green (ICG) in different spots can better find sentinel lymph nodes during surgery for endometrial cancer. It may help doctors remove fewer nodes and reduce side effects.
Jinan, ShandongAges 18–80 - NCT06684418Recruiting
AI to find hidden cancer spread in early lung cancer
This trial uses artificial intelligence to predict if early-stage lung cancer has spread to nearby lymph nodes. It aims to help doctors make better treatment decisions for patients with stage 1 lung cancer.
ShanghaiAges 18 years+ - NCT07686016Recruiting
Radiation therapy for prostate cancer that has spread to a few spots
This trial studies the use of radiation to the prostate and to all visible spots where cancer has spread, in men who have up to 10 small areas of spread when first diagnosed. The goal is to see if this approach can help control the cancer.
Zamość, Lublin VoivodeshipAges 18 years+ - NCT06713161Recruiting
New dye to spot breast cancer during surgery
This study tests a special dye that helps surgeons see breast cancer tissue and nearby lymph nodes more clearly during surgery. The goal is to make sure all cancer is removed while sparing healthy tissue.
Kunming, YunnanAges 18–75
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Common questions
- Are there clinical trials for lymph node disease?
- Yes. Clin2 currently lists 176 recruiting lymph node disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymph node disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymph node disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.