Clinical trials
Lymph Node Disease clinical trials
Below are recruiting lymph node disease clinical trials, each written for real people, not researchers. We’re tracking 176 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07746258Recruiting
Checking if skin cancer has spread to nearby lymph nodes
This study uses a test to see if a type of skin cancer called high-risk cutaneous squamous cell carcinoma has spread to lymph nodes. The goal is to learn more about how to detect spread early, which could help guide treatment decisions.
Badalona, BarcelonaAges 18 years+ - NCT07622836Recruiting
Chemotherapy plus QL1706 for high-risk triple-negative breast cancer
This study tests whether adding a new immunotherapy drug called QL1706 to standard chemotherapy after surgery can help patients with aggressive triple-negative breast cancer that has spread to lymph nodes. The goal is to see if this combination prevents cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT06722612Recruiting
Chemo plus targeted therapy for high-risk HER2+ early breast cancer
This trial tests whether combining chemotherapy with targeted therapy works better for women with high-risk, HER2 positive early breast cancer that hasn't spread to lymph nodes. If you've had surgery and your tumor fits certain high-risk features, you may be eligible to join.
Beijing, Beijing MunicipalityAges Any age - NCT06711068Recruiting
Chemotherapy plus targeted therapy for HER2+ early breast cancer
This trial tests whether adding targeted therapy to chemotherapy after surgery can help prevent HER2-positive early breast cancer from coming back. It is for patients whose cancer has not spread to lymph nodes and who have certain tumor sizes and features.
Beijing, Beijing MunicipalityAges Any age - NCT06693375RecruitingPhase 2
Testing a new imaging agent for rectal cancer lymph nodes
This trial tests a new nanoparticle-based imaging agent to better see lymph nodes near the rectum. It first checks healthy volunteers for safety, then studies people with rectal cancer to see if it can help guide surgery.
UppsalaAges 18–99 - NCT06528743Recruiting
Testing primer shot radiotherapy for lung cancer
This study is testing a new way of giving a very short, high-dose radiation treatment (called 'primer shot' radiotherapy) for people with non-small cell lung cancer. The goal is to see if it’s safe and practical for shrinking the main lung tumor and relieving symptoms.
AmsterdamAges 18 years+ - NCT06449313RecruitingPhase 2
Immunotherapy before lung cancer surgery for stage 3 disease
This trial tests whether giving chemotherapy plus immunotherapy before surgery can help shrink stage 3 lung cancer and improve outcomes. The goal is to make the tumor easier to remove and possibly lower the chance of it coming back.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07293247RecruitingPhase 2
Targeted radiation after lung cancer surgery
This trial tests if targeted radiation after surgery can help people with non-small cell lung cancer who still have cancer in their lymph nodes after chemotherapy. Participants will have had surgery and chemotherapy before starting radiation.
Jonesboro, ArkansasAges 18 years+ - NCT07466316RecruitingPhase 3
Comparing chemo schedules for intermediate-risk rhabdomyosarcoma
This trial compares two different chemotherapy schedules for children and young adults with intermediate-risk rhabdomyosarcoma (a type of muscle cancer). One group gets a higher dose of chemotherapy over a shorter period, while the other gets a lower dose plus maintenance therapy for a longer time. The goal is to see which approach works better.
Los Angeles, CaliforniaAges Up to 50 years - NCT06540196Recruiting
AI tool to predict lung cancer spread during ultrasound staging
This trial tests an artificial intelligence platform that helps doctors predict if lymph nodes in the chest contain cancer during a routine ultrasound procedure. It aims to make staging more accurate for people with suspected or confirmed non-small cell lung cancer.
Hamilton, OntarioAges 18 years+ - NCT03587480Recruiting
Surgery methods after chemo-radiation for stage 3 rectal cancer
This trial compares two different surgery approaches after chemo-radiation for stage 3 rectal cancer. It aims to see which operation helps control the cancer more effectively while keeping surgery as safe as possible.
Guangzhou, GuangdongAges 18–75 - NCT03719547Recruiting
Robot surgery for certain early cervical cancer cases
This trial studies whether robot-assisted surgery can be used safely and effectively for certain early-stage cervical cancers. It may help by using a precise surgical approach to remove the cancer while matching standard care for eligible patients.
StockholmAges 18 years+ - NCT05132283Recruiting
Lymph node removal for urologic cancers with advanced imaging
This study uses a special MRI scanner in the operating room to help guide lymph node removal during surgery for urologic cancers like bladder, prostate, testicular, kidney, urethral, or penile cancer. It aims to see if this real-time imaging can make the surgery more precise.
Boston, MassachusettsAges 18 years+ - NCT04443478Recruiting
Keyhole versus open lymph node surgery for junction cancer
This trial compares two ways of removing lymph nodes during surgery: keyhole (laparoscopic) versus open surgery. It is for people with esophagus-stomach junction adenocarcinoma, aiming to see which approach works better and is safer.
Beijing, Beijing MunicipalityAges 18–80 - NCT04606030Recruiting
Tested lymph surgery for breast-cancer–related arm swelling
This trial studies a specialized lymph surgery (called VLNT, moving lymph tissue) to treat swelling in an arm caused by breast cancer treatment. It may help reduce lymphedema that doesn’t fully improve with compression and elevation.
Chicago, IllinoisAges 18–75 - NCT04636710Recruiting
Treatment approach study for stage III inflammatory breast cancer
This study looks at how to best plan local treatments (like surgery and/or radiation) for people with stage III inflammatory breast cancer. It may help doctors refine care plans for this aggressive subtype by studying how patients are treated and what outcomes they have.
Boston, MassachusettsAges 18 years+ - NCT04741737Recruiting
Repeat lymph node biopsy for recurrent breast cancer
This study tests whether repeating a specific lymph node biopsy (sentinel lymph node biopsy) is safe and useful in people whose breast cancer has come back in the same breast. It may help doctors better understand whether lymph nodes are involved and guide next steps after surgery.
SeoulAges 19 years+ - NCT04858880Recruiting
Personalized radiation for PSA rise after prostate surgery
This study tests a tailored (personalized) radiation plan for men whose PSA (“prostate blood test”) rises after prostate surgery but who have no detectable spread on scans. It may help control cancer growth by targeting the right area based on your situation.
JönköpingAges 18 years+ - NCT04959474Recruiting
Pre-surgery radiation study with or without calorie restriction
This trial looks at whether a planned calorie-reduction diet before surgery can change how early breast cancer responds to a short course of radiation. It may help people understand if diet could improve outcomes alongside standard pre-surgery treatment.
Philadelphia, PennsylvaniaAges 40 years+ - NCT05116475RecruitingPhase 3
New prostate cancer trial adding darolutamide to standard treatment
This Phase 3 trial tests whether adding darolutamide to standard hormone therapy and radiation works better than standard treatment alone for newly diagnosed prostate cancer that has spread to pelvic lymph nodes. If you qualify, you may receive darolutamide or a placebo alongside long-term hormone therapy and radiation.
Chambray-lès-ToursAges 18–120 - NCT05184803RecruitingPhase 2
Pre-surgery chemo for advanced stomach cancer with lymph spread
This Phase 2 study tests a combination chemotherapy regimen given before surgery for stomach cancer that cannot be fully removed (unresectable), including spread to lymph nodes. The goal is to shrink the cancer and improve control with a well-known set of medicines given in a specific order.
Seoul, SeoulAges 19 years+ - NCT05319015RecruitingPhase 2
Lenvatinib plus pembrolizumab before kidney surgery for IVC tumor
This trial studies lenvatinib and pembrolizumab given before surgery to treat kidney cancer that has grown into a large vein (the IVC) near the liver or heart. The goal is to shrink or control the tumor thrombus and make treatment and surgery more effective and safer.
Dallas, TexasAges 18 years+ - NCT05345158Recruiting
Robotic surgery first for early-stage seminoma testicular cancer
This trial studies whether a robotic operation (removing cancerous lymph nodes in the back of the belly) is a good first treatment for certain early-stage testicular seminoma cases. It aims to cure cancer while avoiding or delaying other treatments, and uses follow-up plans to check results.
Toronto, OntarioAges 18 years+ - NCT05593458RecruitingPhase 3
Stomach cancer surgery before chemo: artery-based or drip chemo
This trial compares two ways of giving chemotherapy before surgery for locally advanced stomach or stomach–esophagus cancer: chemo sent through an artery versus chemo given through an IV line. It also studies adding PD-1 immunotherapy to see which approach works better and is safer.
Hangzhou, ZhejiangAges 18–75
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Common questions
- Are there clinical trials for lymph node disease?
- Yes. Clin2 currently lists 176 recruiting lymph node disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lymph node disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lymph node disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.