Clinical trials
Maintenance Therapy clinical trials
Below are recruiting maintenance therapy clinical trials, each written for real people, not researchers. We’re tracking 119 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07013149Recruiting
Switching PAH medicines: does it change your risk?
This study looks at how changing from one PAH medicine (ambrisentan) to another (bosentan) affects your disease risk over time. It compares people who made the switch to those who stayed on ambrisentan.
São Paulo, São PauloAges 18 years+ - NCT06574425Enrolling by invitationPhase 4
Long-term high-flow hemoadsorption for dialysis patients
This study tests a long-term, high-flow hemoadsorption therapy for people on maintenance hemodialysis. It aims to see if the treatment can improve outcomes for those with uremia (built-up waste in the blood).
Beijing, Beijing MunicipalityAges 18 years+ - NCT05959291Recruiting
Stopping long-term anti-HER2 therapy in stable metastatic breast cancer
This study asks whether some people with HER2-positive metastatic breast cancer who have been stable for a long time can safely stop their ongoing (maintenance) anti-HER2 treatment. It also uses blood testing and close imaging follow-up to watch for early signs that treatment needs to restart.
Miami, FloridaAges 18 years+ - NCT07040982RecruitingPhase 1
Asciminib after cell therapy for Ph+ ALL
This trial tests the drug asciminib after a stem cell transplant or CAR T-cell therapy for adults with Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) to help prevent the cancer from coming back.
Duarte, CaliforniaAges 18 years+ - NCT03562169RecruitingPhase 3
Ixazomib with your own stem cell transplant for relapsed myeloma
This trial studies whether adding ixazomib (an oral drug) to a transplant using your own stem cells can control relapsed multiple myeloma better. It may help by strengthening anti-myeloma treatment after the transplant, aiming to delay disease progression.
AberdeenAges 18 years+ - NCT06684444Enrolling by invitationPhase 4
Sleep coaching study for firefighters with sleep troubles
This study tests if health coaching can help career firefighters sleep better. You'll have private coaching sessions by phone or computer.
Tucson, ArizonaAges 18 years+ - NCT05530863Enrolling by invitation
Relaxation methods for insomnia during pregnancy
This study tests relaxation-based approaches to help pregnant people who have trouble falling asleep or waking up during the night. If you meet the sleep and pregnancy timing needs, the goal is to see whether the approach can improve sleep.
Philadelphia, PennsylvaniaAges 18–55 - NCT07489989RecruitingPhase 2
Combination therapy to boost CAR-T for B-cell lymphoma
This trial tests a new combination of drugs to make CAR-T cell therapy work better for people with certain types of B-cell lymphoma. It adds the drugs chidamide and a PD-1 inhibitor to the usual CAR-T treatment, aiming to improve response.
Beijing, Beijing MunicipalityAges 18–85 - NCT07200102RecruitingPhase 1
Selinexor after CAR-T for high-risk multiple myeloma
This trial tests if the drug selinexor can help prevent multiple myeloma from coming back after CAR-T cell therapy. It is for people with high-risk or persistent myeloma who have already received a specific CAR-T treatment called Carvykti.
St Louis, MissouriAges 18 years+ - NCT07291154Recruiting
Using an app to improve dialysis quality
This trial tests if a smartphone app (via WeChat) can help people on dialysis better manage their treatment and improve quality of care. It's for adults who have been on regular dialysis for at least 3 months.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06176534RecruitingPhase 2
Comparing two treatments for advanced breast cancer with low hormone receptor
This trial compares two treatment options for advanced breast cancer that has low hormone receptor levels and is HER2-negative. It tests whether a combination of chemotherapy followed by maintenance therapy works better than a CDK4/6 inhibitor combined with hormone therapy. This is for people who have not had chemotherapy for their advanced disease.
Zhengzhou, HenanAges 18 years+ - NCT06239272RecruitingPhase 1/Phase 2
Personalized treatment for NRSTS in children and young adults
This trial tests a personalized treatment plan for children and young adults with a type of soft tissue sarcoma (NRSTS). It uses a combination of surgery, targeted radiation, and two drugs (pazopanib and selinexor) to fight cancer while reducing side effects. The study is looking for people who have not been treated before for this sarcoma.
Atlanta, GeorgiaAges Up to 30 years - NCT07033819RecruitingPhase 2
Fuzuloparib and apatinib before surgery for ovarian cancer
This trial tests a combination of two oral drugs—fuzuloparib (a PARP inhibitor) and apatinib (which blocks blood vessel growth to tumors)—given before surgery for advanced ovarian cancer that cannot be removed right away. It is for people whose tumors have a specific genetic marker (HRD positive) and who have not had prior cancer treatment.
Beijing, Beijing MunicipalityAges 18–70 - NCT06463236Recruiting
Study of anemia management in dialysis patients
This study is testing a new way to manage anemia (low red blood cells) in people on long-term dialysis. It aims to improve how doctors treat this common issue.
Chengdu, SichuanAges 18 years+ - NCT06736028Recruiting
Ketogenic diet for weight loss maintenance in obesity
This study tests whether a ketogenic diet helps people with obesity keep weight off by changing how your body burns energy and controls appetite. You will follow a low-carb, high-fat diet and be monitored for several months.
Birmingham, AlabamaAges 18–65 - NCT06671535Recruiting
Dialysis filter for itching in hemodialysis patients
This study tests a special type of dialysis filter (made of PMMA) to see if it can reduce severe itching and improve quality of life for people on long-term dialysis. If you have bothersome itching that standard treatment hasn't helped, this trial might be an option for you.
Saint PetersburgAges 18 years+ - NCT06067139Recruiting
Sleep therapy to lower diabetes risk in prediabetes
This study tests if a sleep-focused therapy (cognitive behavioral therapy for insomnia, or CBT-I) can lower diabetes risk in people with prediabetes and insomnia. Participants will receive online therapy sessions and wear a monitor to track blood sugar and sleep.
Portland, OregonAges 22–79 - NCT05231629RecruitingPhase 2
MRD-guided step-by-step treatment for multiple myeloma
This Phase 2 study tests a treatment plan for newly diagnosed multiple myeloma that changes based on MRD results. MRD is a very sensitive lab test that looks for tiny amounts of remaining cancer, which may help tailor therapy to work better and potentially avoid overtreatment.
Birmingham, AlabamaAges 18 years+ - NCT05423275Recruiting
Light treatment to help you stop antidepressants safely
This study tests whether a “light and ion” treatment can help people with major depression (MDD) who are doing well on antidepressants safely reduce or stop them. You must be in remission and be willing to discontinue for reasons like side effects or personal preference.
Vancouver, British ColumbiaAges 19–65 - NCT07189325RecruitingPhase 3
Comparing two ways to manage relapsing-remitting MS
This trial tests if it's safe to stop or reduce anti-CD20 treatment after several years of stable disease, compared to continuing it. It's for people with relapsing-remitting MS who are at least 40 years old and have had no MS activity for the past 3 years on anti-CD20 therapy.
MontpellierAges 40 years+ - NCT05460000RecruitingPhase 2
Niraparib after early ovarian cancer chemo—short vs long
This trial tests whether taking niraparib (a maintenance anti-cancer pill) for a shorter time after 3 cycles of platinum chemotherapy works as well as taking it after 6 cycles. It is for people with advanced ovarian cancer that has been fully removed (no visible tumor) and is “HRD-positive,” meaning it has certain DNA repair weaknesses.
InnsbruckAges 18 years+ - NCT07466316RecruitingPhase 3
Comparing chemo schedules for intermediate-risk rhabdomyosarcoma
This trial compares two different chemotherapy schedules for children and young adults with intermediate-risk rhabdomyosarcoma (a type of muscle cancer). One group gets a higher dose of chemotherapy over a shorter period, while the other gets a lower dose plus maintenance therapy for a longer time. The goal is to see which approach works better.
Los Angeles, CaliforniaAges Up to 50 years - NCT07061977RecruitingPhase 3
New cancer drug combo for advanced cervical cancer
This trial tests if giving the immunotherapy drug pembrolizumab before and after standard chemoradiation works better than the standard approach for people with high-risk cervical cancer that has spread locally.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for maintenance therapy?
- Yes. Clin2 currently lists 119 recruiting maintenance therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a maintenance therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a maintenance therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.