Clinical trials
Malignant Biliary Obstruction clinical trials
Below are recruiting malignant biliary obstruction clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06613945Recruiting
Comparing two ways to open blocked bile ducts in liver cancer
This study compares two procedures to drain bile from the liver in people with blocked bile ducts caused by cancer that cannot be removed. It looks at whether using an ultrasound-guided approach along with standard ERCP works better than ERCP alone.
Al Mansurah, Dakahlia GovernorateAges 18 years+ - NCT07559968Recruiting
Comparing two types of stents for bile duct cancer blockage
This study compares two different metallic stent designs to help keep bile ducts open in patients with advanced bile duct cancer. You would already have a temporary drainage tube in place and be scheduled for a permanent stent, so this trial tests which stent type works better.
Seoul, SeoulAges 19 years+ - NCT07407491RecruitingPhase 2
Antibiotic during ERCP for bile duct infection
This trial tests if giving an antibiotic directly into the bile duct during an ERCP procedure helps treat acute cholangitis better than standard care. If you have mild or moderate cholangitis and are scheduled for ERCP within 48 hours, you may be a candidate.
Cheras, Kuala LumpurAges 18 years+ - NCT06671418Enrolling by invitationPhase 3
Stenting vs drainage for blocked bile ducts from cancer
This study compares two ways to open blocked bile ducts near the liver due to cancer that cannot be removed. One method uses a stent placed through the skin (percutaneous stenting), and the other uses a tube placed through a scope (endoscopic drainage). The goal is to see which approach works better for relieving jaundice and improving quality of life.
RotterdamAges Any age - NCT07640243Recruiting
Sedation Methods for Bile Duct Drainage Procedures
This study compares different sedation (sleep) methods used during a procedure to drain blocked bile ducts. Researchers want to see which sedation approach gives patients the best experience and fastest recovery.
Ankara, AnkaraAges 18 years+ - NCT05169398Recruiting
EUS-guided bile drainage with a new metal stent
This trial tests a newer, ultrasound-guided procedure to drain blocked bile flow using a special metal stent. It may help people who have bile duct blockage but could not have their bile drained successfully with standard ERCP.
Hong KongAges 18 years+ - NCT05546372Recruiting
Radiofrequency ablation to treat blocked bile ducts from bile cancer
This study tests whether radiofrequency ablation can improve treatment for people who have a malignant (cancer-related) blockage of the bile ducts near the liver (perihilar cholangiocarcinoma). It’s for patients who are not good candidates for curative surgery and who need bile-duct drainage using a specific stent (uSEMS).
AmsterdamAges 18 years+ - NCT04929821Recruiting
Study of a dissolvable stent for bile duct narrowing
This study is testing a new type of stent that eventually dissolves on its own. The stent is placed in a narrowed bile duct to open it up and let bile flow properly. This might help people with strictures caused by scarring, stones, past surgeries, or certain bile duct cancers.
Hong KongAges 18 years+ - NCT07096895Recruiting
Special Endoscopic Procedure for Blocked Bile Duct Access
This trial tests a special endoscopic procedure (EDEE) to reach the bile duct when the usual pathway is blocked, which can happen with certain benign or malignant conditions. If standard methods can't access the area, this approach may offer an alternative.
DüsseldorfAges 18 years+ - NCT05246657Recruiting
EUS procedure to bypass blocked bile ducts when ERCP fails
This trial studies a new way to access the bile ducts using a scope guided by ultrasound when standard ERCP can’t be done or doesn’t work. It may help people with non-cancer (benign) bile duct blockages get the bile flowing again.
ValladolidAges 18 years+ - NCT04645160RecruitingPhase 1/Phase 2
Tivozanib for bile duct and gallbladder cancers after chemotherapy
This Phase 1/2 trial tests tivozanib (a targeted anti-cancer drug) in people with bile duct or gallbladder cancer that cannot be removed by surgery and has already been treated with first-line chemotherapy. The study looks at how well the drug works and how safe it is in this setting.
Bethesda, MarylandAges 18 years+ - NCT07609641Recruiting
Surgery for Bile Duct Cancer: Two Surgical Approaches
This trial compares two different surgical approaches for treating bile duct cancer (cholangiocarcinoma) to see which method works better and is safer. You would undergo surgery and have your recovery and outcomes closely monitored.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT06071507Recruiting
Comparing treatments for stomach blockage in pancreatic cancer
This trial compares three ways to relieve a stomach or duodenal blockage caused by pancreatic cancer: placing a stent, performing a bypass with a thin tube (endoscopy), or surgical bypass. It aims to find which option helps patients eat and feel better sooner.
ParisAges 18 years+ - NCT05705492RecruitingPhase 2
Olanzapine to help cancer-related weight and appetite loss
This Phase 2 trial tests whether olanzapine can help people with advanced cancer who are losing weight and not eating enough. It looks for improvements in appetite and weight while you receive your first-line palliative cancer treatment.
Portland, OregonAges 18 years+ - NCT07763301RecruitingPhase 1
Vaccine for advanced liver, bile duct, or pancreatic cancer
This trial is testing an investigational vaccine (YMN-136) for people with advanced liver, bile duct, or pancreatic cancer that has not responded to standard treatments or is not tolerated. The vaccine aims to help your immune system fight the cancer. It may be an option if standard treatments have failed.
Chengdu, SichuanAges 18–75 - NCT05733000RecruitingPhase 2
CPI-613 plus hydroxychloroquine with chemo for advanced solid tumors
This trial tests a drug called CPI-613 (devimistat) combined with hydroxychloroquine along with either 5-fluorouracil or gemcitabine chemo. It’s for people with advanced cancers that have stopped responding to standard treatments, aiming to shrink tumors and slow cancer growth.
Chicago, IllinoisAges 18 years+ - NCT05285358RecruitingPhase 1
Aerosol chemo plus standard drugs for bile duct and gallbladder cancer
This trial tests a new way to give the drug paclitaxel directly into your belly as a mist, along with two standard chemo drugs given through your veins, for bile duct or gallbladder cancer that has spread to the lining of the belly. The goal is to see if this approach can better control the cancer in the belly.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for malignant biliary obstruction?
- Yes. Clin2 currently lists 17 recruiting malignant biliary obstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malignant biliary obstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malignant biliary obstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.