Clinical trials
Malignant Neoplasm clinical trials
Below are recruiting malignant neoplasm clinical trials, each written for real people, not researchers. We’re tracking 500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05830058RecruitingPhase 2
PET-guided focused radiation for limited worsening lung, melanoma, kidney cancer
This Phase 2 study tests whether using a PET scan to guide focused radiation (SBRT) can control a small number of cancer spots that are starting to grow despite prior treatment. It may help patients avoid wider radiation by targeting only the limited progressing areas.
Duarte, CaliforniaAges 18 years+ - NCT05882175Recruiting
Checking how well an index predicts blood cancer care
This trial looks at how well a measurement called the OHI Index works for people with blood cancers. It may help doctors better assess risk or needs, but it mainly focuses on validating the tool rather than testing a new drug.
Kfar SabaAges 18 years+ - NCT05979610RecruitingPhase 2
Reiki therapy for symptom relief during gynecologic radiation
This trial tests whether adding Reiki therapy (a gentle hands-on relaxation technique) can help reduce side effects like pain and anxiety during brachytherapy (internal radiation) for women with gynecologic cancers. Participants will be randomly assigned to receive Reiki plus usual care or usual care alone.
Salt Lake City, UtahAges 18 years+ - NCT06250595Recruiting
European rare blood disorder registry
This study is building a registry of people with rare blood diseases. By joining, you help doctors learn more about these conditions and improve future care.
Barcelona, CataloniaAges Up to 100 years - NCT06265285RecruitingPhase 2
Nivolumab at home vs. clinic for cancer treatment
This study compares giving the immunotherapy drug nivolumab as a shot under the skin at home versus in the clinic. It is for people with certain cancers who are already taking or starting nivolumab.
Jacksonville, FloridaAges 18 years+ - NCT06377696RecruitingPhase 2
Metformin study for brain tumor survivors after radiation
This study tests whether metformin, a common diabetes medicine, can help protect thinking and memory skills in people who have had radiation for a brain tumor. You will use a smartwatch and take online tests from home to track your progress.
Rochester, MinnesotaAges 18 years+ - NCT06578650Recruiting
Restrata Mat for Skin Cancer Surgery Wounds
This study tests a special fiber mat called Restrata that is placed in the wound after skin cancer removal to help it heal. The mat acts as a scaffold for new skin growth and may help close the wound without needing a skin graft.
Las Vegas, NevadaAges 18 years+ - NCT06630416RecruitingPhase 2
Pemetrexed for advanced bladder and other cancers with certain gene changes
This trial tests if a chemotherapy drug called pemetrexed works better in advanced bladder cancer or other solid tumors that have specific genetic changes (MLL4, UTX, or MTAP). It is for people who have already tried at least two prior treatments.
Chicago, IllinoisAges 18 years+ - NCT06667726RecruitingPhase 2
New PET scan for better brain tumor care
This trial studies a special PET scan called 18F-DOPA PET/CT to see if it can help doctors better manage brain tumors. It may be used before surgery, for radiation planning, or when MRI results are unclear.
Rochester, MinnesotaAges 18 years+ - NCT06675643Recruiting
Remote monitoring of side effects from melanoma treatment
This study tests a smartphone app called Vigilant that helps monitor side effects from a melanoma treatment (ipilimumab and nivolumab). You may be able to join if you are about to start this therapy.
Rochester, MinnesotaAges 18 years+ - NCT06043713RecruitingPhase 1
T-cell therapy for KRAS G12V solid tumors
This trial tests a personalized T-cell therapy designed to recognize and attack cancer cells with a specific KRAS G12V mutation. It is for people with metastatic solid tumors that have this mutation and a specific immune type (HLA-A*11:01).
Seattle, WashingtonAges 18 years+ - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Dublin, CaliforniaAges 18 years+ - NCT07291414Recruiting
Tracking cancer medication safety with a self-monitoring platform
This trial tests a platform where you can track your experiences and concerns about cancer medications. It aims to help you and your care team manage medication safety.
Ann Arbor, MichiganAges 18 years+ - NCT00488878Recruiting
Collecting information for certain low-grade ovarian or peritoneal tumors
This study collects health information from people whose ovarian or peritoneal cancer started as a low-grade type but later changed to a higher-grade cancer. It may help researchers better understand how these tumors progress and what to expect over time.
Houston, TexasAges Any age - NCT01638130Recruiting
Study of support needs in high-grade brain tumor patients
This study asks people with a high-grade brain tumor and their caregivers about their experiences and support needs. It may help researchers understand what patients and families need during and after chemotherapy.
Leuven, Vlaams-BrabantAges 18 years+ - NCT02285582Recruiting
Rare blood disorder registry for histiocytic conditions
This study is a registry that collects information about people diagnosed with rare histiocytic disorders. It helps doctors better understand these conditions over time and may improve future care.
Birmingham, AlabamaAges Any age - NCT07485855RecruitingPhase 3
Flu vaccine study for blood cancer patients
This trial tests how well the flu vaccine works in people with blood cancers like lymphoma, leukemia, or multiple myeloma. It aims to find the best vaccination strategy to protect you during treatment.
SeoulAges 19 years+ - NCT07664579Recruiting
Couples coping together against cancer support program
This trial tests a supportive care program for couples facing cancer. It helps you and your partner work together to manage the challenges of a cancer diagnosis.
Duarte, CaliforniaAges 18 years+ - NCT06606990RecruitingPhase 1
Testing the drug CX-5461 for advanced solid tumors
This trial tests a new drug called CX-5461 (also known as pidnarulex) in people whose cancer has spread and hasn't been helped by standard treatments. It looks at how your body responds to the drug, which may target cancers with specific DNA repair problems.
Bethesda, MarylandAges 18 years+ - NCT06089083Recruiting
Helping gynecologic cancer patients with frailty recover function
This study tests a program to help gynecologic cancer patients who are frail improve their physical function and quality of life during treatment. It aims to see if extra support can help you stay stronger and recover better.
San Francisco, CaliforniaAges 18 years+ - NCT06051695RecruitingPhase 1/Phase 2
CAR T cell therapy for mesothelin-positive solid tumors
This trial tests a new type of immune cell therapy (CAR T-cells) designed to target cancer cells that have a protein called mesothelin but have lost a marker that lets them hide from the immune system. It's for people with advanced solid tumors who have already tried standard treatments.
Gilbert, ArizonaAges 18 years+ - NCT04221893Recruiting
Radiation therapy for metastatic gastrointestinal cancers
This trial tests whether adding radiation therapy to your current immunotherapy can help control cancer that has spread in the digestive system. It aims to improve symptoms and possibly slow the cancer's growth.
San Francisco, CaliforniaAges 18 years+ - NCT04870762RecruitingTeam says not enrollingPhase 2
3D-printed tongue stents during head and neck radiation
This Phase 2 study tests whether customized 3D-printed stents can be used safely during head and neck radiotherapy. If you’re having radiation (with or without chemotherapy), the stent may help make treatment easier and more precise, potentially improving the experience and outcomes.
Phoenix, ArizonaAges 18 years+ - NCT05134142Recruiting
Quality of life after hemipelvectomy for pelvic tumors
This study looks at how people with pelvic tumors feel and function after a hemipelvectomy (surgery removing part of the hip/pelvis). It aims to better understand recovery and day-to-day quality of life after this operation.
Houston, TexasAges Any age
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Common questions
- Are there clinical trials for malignant neoplasm?
- Yes. Clin2 currently lists 500 recruiting malignant neoplasm studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a malignant neoplasm trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a malignant neoplasm trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.