Clinical trials
Mechanically Ventilated ICU Patients clinical trials
Below are recruiting mechanically ventilated icu patients clinical trials, each written for real people, not researchers. We’re tracking 126 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06680895Recruiting
FeNO study in ICU patients with breathing support
This study measures a lung inflammation marker called FeNO in ICU patients on a breathing machine. It may help doctors understand lung health and guide treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07066605Recruiting
Dexmedetomidine for agitation during breathing tube removal
This trial tests whether a sedative called dexmedetomidine can reduce agitation in ICU patients when they are being weaned off a breathing tube. If you experience restlessness or agitation during the weaning process, this medication might help you stay calm.
SohagAges 19 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+ - NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT07362537Recruiting
Feeding while on stomach for severe lung failure
This study tests if giving nutrition through a feeding tube is safe and effective for patients with severe lung failure who need to lie on their stomach to help breathing. It may help doctors understand how to best feed patients during this treatment.
Nanjing, JiangsuAges 18–85 - NCT06970262Recruiting
Fecal transplant for tough lung infections on a ventilator
This study tests whether a treatment called fecal microbiota transplantation (FMT) can help clear stubborn lung infections (MDRO) in people who are in the ICU on a ventilator. The goal is to see if FMT can improve recovery and reduce the risk of further organ problems.
WuhanAges 18–70 - NCT04110613Recruiting
Early feeding after PEG tube placement in ICU patients
This trial tests whether starting tube feeds soon after a PEG tube is placed is safe and helpful for mechanically ventilated ICU patients. PEG is a feeding tube placed through the belly, and early feeding may support recovery if your stomach can handle it.
Roanoke, VirginiaAges 18–100 - NCT04801589RecruitingPhase 3
Guided sedation for children on a breathing machine
This study tests a “goal-directed” approach to sedation (giving the right amount based on target goals) for children who need a breathing machine in the pediatric ICU. The goal is to reduce brain and recovery side effects while keeping children comfortable and safe.
Nashville, TennesseeAges 10 months–11 years - NCT05525702Recruiting
VR sessions to lower confusion in ICU patients
This trial tests whether virtual reality (VR) activities can reduce delirium—new, sudden confusion—in people staying in the ICU. It may help patients feel clearer and more oriented during a longer ICU stay.
Beijing, Beijing MunicipalityAges 18–90 - NCT07656259Recruiting
Comparing breathing support methods in the heart ICU
This study compares different ways to support breathing in patients who need a ventilator in the cardiac intensive care unit. It aims to find the best approach for people with certain heart conditions, like cardiogenic shock or heart failure.
Rochester, MinnesotaAges 18 years+ - NCT06514781Recruiting
Comparing sedation methods for severe pneumonia in the ICU
This study looks at different ways to sedate patients on a breathing machine in the ICU who have severe pneumonia. The goal is to find which approach works best for recovery and comfort.
Changsha, HunanAges 18 years+ - NCT06532994Recruiting
Prediction tool for recovery after critical illness
This study looks at how well people recover after critical illness. It tests a prediction tool to help guide rehabilitation for patients who needed a breathing machine and started rehab in the ICU.
Wuhan, HubeiAges 18–90 - NCT06785571RecruitingPhase 2/Phase 3
Pain relief study for ICU patients on a ventilator
This study tests a painkiller called nalbuphine for ICU patients on a breathing machine. It aims to see if it controls pain as well as or better than usual care, with fewer side effects.
Wuhan, HubeiAges 18–80 - NCT06911450Recruiting
Ultrasound test for lung strain in ICU patients
This study uses a special ultrasound technique to measure how the lungs stretch (pleural strain) during breathing. It aims to see if this measurement works in ICU patients, both those breathing on their own and those on a ventilator, and how it relates to the pressure needed to inflate the lungs.
Wuhu, AnhuiAges 18–75 - NCT07377162Recruiting
Hyperoxia effects on brain blood flow in ICU patients
This trial studies how giving extra oxygen (hyperoxia) affects blood flow in the brain for patients on a breathing machine in the intensive care unit. The goal is to see if short bursts of higher oxygen levels are safe and how they change brain activity.
BrusselsAges 18 years+ - NCT07395297Recruiting
Airway clearance therapy for ICU lung infections
This trial tests a new airway clearance device in ICU patients with pneumonia. It may help clear mucus from your lungs and improve breathing without needing a breathing tube.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07485244Recruiting
EEG brain monitoring in ICU patients at risk for delirium
This study uses a simple headband (EEG) to monitor brain activity in ICU patients who are at high risk for delirium. The goal is to see if the EEG can help detect delirium earlier, so doctors can provide better care.
Nashville, TennesseeAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06607055Recruiting
Immune markers in ICU patients with pneumonia
This study looks at how the immune system reacts in ICU patients on a ventilator who have pneumonia. By measuring immune markers, the researchers hope to better understand and predict complications like ventilator-associated pneumonia.
Aix-en-ProvenceAges 18 years+ - NCT06400095Recruiting
Breathing Machine Patterns to Predict Recovery in Severe Lung Failure
This study looks at how the breathing machine settings and lung function can help predict recovery in people with severe ARDS. You may be able to join if you are on a ventilator for sudden lung failure and have severe ARDS, as long as you don't have certain other health issues.
Saint Cloud, MinnesotaAges 19–80 - NCT06410664Recruiting
Longer use of heat-moisture exchangers in the ICU
This study tests if keeping a device called a heat and moisture exchanger (HME) on a breathing tube for longer periods is safe and effective for ICU patients who need breathing support. It aims to reduce infections and complications.
Prague, Česká RepublikaAges 18 years+
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Common questions
- Are there clinical trials for mechanically ventilated icu patients?
- Yes. Clin2 currently lists 126 recruiting mechanically ventilated icu patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanically ventilated icu patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanically ventilated icu patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.