Clinical trials
Mechanically Ventilated ICU Patients clinical trials
Below are recruiting mechanically ventilated icu patients clinical trials, each written for real people, not researchers. We’re tracking 116 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06692400Recruiting
Suctioning, pain, and blood markers in intubated patients
This study looks at how routine suctioning of the breathing tube affects pain levels and certain substances in the blood in adults who are on a breathing machine for serious infections like flu, pneumonia, COVID, or sepsis. It may help doctors better understand and manage your comfort during this procedure.
Loma Linda, CaliforniaAges 18 years+ - NCT07437846Recruiting
How lung pressure settings affect breathing effort in ICU patients
This trial looks at how different breathing support settings (called PEEP) affect how hard your lungs have to work when you are on a breathing machine. The goal is to find the best setting to make breathing easier for you.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07536750Recruiting
Comparing Two Sedation Drugs for ICU Patients on Breathing Support
This study compares two medications (ciprofol and propofol) used to keep ICU patients calm and comfortable while they receive non-invasive breathing support, such as oxygen masks or tubes that help them breathe without a breathing tube in their windpipe. Researchers want to see which drug works better and is safer.
Guangzhou, GuangdongAges 18 years+ - NCT07467551Recruiting
Pain scale study for patients on breathing machines
This study tests a pain scale for patients who are on a breathing machine and cannot speak. It aims to help doctors better recognize pain in these patients.
IstanbulAges 18–85 - NCT07656155Enrolling by invitation
Digital health study for high-risk ICU patients on ventilators
This study looks at patients who are in the ICU, on a breathing machine, and have a long-term health condition. It aims to use digital tools to better understand these high-risk patients and improve their care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07307066Recruiting
Ventilation feedback study for lung protection in ARDS
This study tests a computer system that gives real-time breathing machine advice to help protect the lungs of patients with severe lung injury (ARDS). It may help doctors adjust the ventilator settings to cause less damage.
Qujing, YunnanAges 18–75 - NCT07105202RecruitingPhase 4
Shorter weaning from ventilator with levosimendan
This study tests if a heart medication called levosimendan helps people get off the breathing machine (ventilator) faster. It's for people who have been on a ventilator for more than 48 hours and have already tried and failed to breathe on their own.
Arnhem, GelderlandAges 18 years+ - NCT07199881Recruiting
Breathing effort study after major abdominal surgery
This study checks how your breathing effort changes with different levels of breathing support from the ventilator after major abdominal surgery. It helps doctors find the best settings to help you breathe comfortably while you recover.
Bangkok, BangkoknoiAges 18 years+ - NCT05865314Recruiting
Nutrition plus early therapy for adults in long ICU stays
This trial studies whether a planned nutrition plan, along with early physiotherapy (physical therapy), can improve outcomes for adults who expect to stay in the ICU for at least 7 days. It includes people who need feeding through a tube and/or special IV nutrition while on a breathing machine.
Geneva, Canton of GenevaAges 18 years+ - NCT06612242Recruiting
Early vs. late tracheostomy in Guillain-Barre patients
This trial looks at whether having a tracheostomy (a breathing tube placed through the neck) earlier or later helps people with Guillain-Barre syndrome who need a breathing machine. It reviews past cases to see which timing leads to better recovery.
Kfar SabaAges 18 years+ - NCT05440851Recruiting
Testing different treatments for severe breathing failure in ICU
This platform trial studies which treatment works best for adults with sudden, severe breathing failure needing oxygen or a breathing machine in the ICU. It may help patients by matching them to the most appropriate treatment strategy and tracking outcomes to improve care.
Tucson, ArizonaAges 18 years+ - NCT07313956Enrolling by invitation
Breathing machine method study in the ICU
This study looks at how different settings on the breathing machine (ventilator) are used for critically ill adults in the ICU. It may help doctors improve care for people who need a breathing tube.
Chicago, IllinoisAges 18 years+ - NCT06014138RecruitingPhase 2/Phase 3
Volatile sedation study for ARDS patients
This trial is comparing a new type of inhaled sedative (volatile sedation) to usual IV sedatives for people with ARDS who are on a ventilator in the ICU. It aims to see if it can help patients breathe better and recover more quickly.
London, LondonAges 17 years+ - NCT05515484RecruitingPhase 2
Test inflatable bag to help lungs work better when prone
This Phase 2 study tests whether using an inflatable air bag can improve how well the lungs stretch and work for people with ARDS while they are lying face-down (prone) on a ventilator. If you qualify, the study may help determine whether this positioning support improves breathing and lung comfort.
AmiensAges 18 years+ - NCT06837402Enrolling by invitation
Non-invasive ventilation in Argentine ICUs: an observational study
This study looks at how non-invasive breathing support (like a mask or machine) is used in ICUs across Argentina. It helps doctors understand patterns of care so they can improve treatment for patients with breathing problems.
CABA, Buenos AiresAges 18 years+ - NCT07646249Recruiting
Best breathing support after surgery in the ICU
This study compares different ways of helping patients breathe after surgery while they're being moved to the intensive care unit. Researchers want to find the safest and most effective method for patients who need a breathing tube.
Alessandria, ItalyAges 18 years+ - NCT06819462Recruiting
Inhaled colistin to prevent ventilator pneumonia in brain injury patients
This trial tests whether giving an inhaled antibiotic called colistin can prevent pneumonia in patients with brain injuries who are on ventilators. If effective, it could reduce lung infections and improve recovery.
Nanjing, JiangsuAges 18–80 - NCT06680895Recruiting
FeNO study in ICU patients with breathing support
This study measures a lung inflammation marker called FeNO in ICU patients on a breathing machine. It may help doctors understand lung health and guide treatment.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07463885Recruiting
Breathing on your own vs machine breathing for low oxygen
This study tests whether letting patients with serious breathing problems breathe on their own (with a breathing tube still in place) is better than the usual way of using the ventilator to do all the breathing. It may lead to faster recovery and less harm.
Oslo, OsloAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT07810166Recruiting
Comparing two weaning methods before tracheostomy removal
This study compares two ways to prepare patients with a tracheostomy (a breathing tube in the neck) for having it removed. It tests whether a standard method or using a special valve (incremental dead space) works better for safe removal.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07656259Recruiting
Comparing breathing support methods in the heart ICU
This study compares different ways to support breathing in patients who need a ventilator in the cardiac intensive care unit. It aims to find the best approach for people with certain heart conditions, like cardiogenic shock or heart failure.
Rochester, MinnesotaAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07485244Recruiting
EEG brain monitoring in ICU patients at risk for delirium
This study uses a simple headband (EEG) to monitor brain activity in ICU patients who are at high risk for delirium. The goal is to see if the EEG can help detect delirium earlier, so doctors can provide better care.
Nashville, TennesseeAges 18 years+
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Common questions
- Are there clinical trials for mechanically ventilated icu patients?
- Yes. Clin2 currently lists 116 recruiting mechanically ventilated icu patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mechanically ventilated icu patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mechanically ventilated icu patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.