Clinical trials
Metabolic Effects clinical trials
Below are recruiting metabolic effects clinical trials, each written for real people, not researchers. We’re tracking 201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06647368Recruiting
Measuring brain sugar use with glucagon
This study tests a new way to measure how the brain uses sugar (glucose) to see if the hormone glucagon affects it. It may help researchers understand how certain hormones work in the body.
CopenhagenAges 25–70 - NCT06837376Recruiting
Metabolic testing and carbs education for teen female athletes
This study looks at whether metabolic testing and education can change how teenage female athletes think about eating carbohydrates. It may help you understand how your body uses energy.
Bradenton, FloridaAges 13–19 - NCT06779201Recruiting
Fasting and its effects on metabolism and immunity
This study looks at how fasting affects your body's metabolism and immune system. It may help researchers understand if planned periods of not eating can improve health.
BeijingAges 18–65 - NCT06973980Recruiting
High-intensity exercise for weight loss in young adults
This study tests whether high-intensity interval training (short bursts of intense exercise) can improve health in sedentary young adults with obesity. If you are between 20 and 35, have a BMI of 30 to 35, and do little to no exercise, this trial may be a good fit.
FamagustaAges 20–35 - NCT06962605Recruiting
Running in short bursts and metabolic health
This trial looks at how doing short, repeated runs (intermittent running) can affect your metabolism and overall health. It's for men who are already active and want to see if this type of exercise helps them stay healthy.
TaipeiAges 20–45 - NCT06704516RecruitingPhase 1
HRT and fatty liver disease in menopausal women – a pilot study
This study tests whether starting hormone replacement therapy (HRT) improves liver health in women with menopause and fatty liver disease (MASLD). It aims to understand how HRT might help reduce fat in the liver.
Oxford, OxfordshireAges 18 years+ - NCT06723626Recruiting
Recovery blend for elderly sepsis patients
This study tests whether giving a special combination of hydrocortisone, vitamin C, and vitamin B1 helps older adults with sepsis recover better. It looks at how the treatment affects tiny blood vessels and overall survival.
Nanjing, JiangsuAges 60–85 - NCT04410003RecruitingPhase 1
Stool-sample capsules to study gut microbiome in unexplained atherosclerosis
This early-phase study tests whether taking stool-based capsules can change gut bacteria in people with severe atherosclerosis that can’t be explained by usual risk factors. Researchers also measure related metabolic (body chemistry) and microbiome (gut bacteria) changes to see how this approach might help.
London, OntarioAges 18 years+ - NCT05962190Recruiting
Short-term extra fat intake to study liver metabolism
This study tests what happens to the liver and fat metabolism when you eat extra fat for a short time. It may help researchers understand how diet affects liver function and metabolism in otherwise stable adults.
OxfordAges 18–65 - NCT06759324Recruiting
Kombucha for weight: live vs. pasteurized effects
This study compares the effects of live kombucha versus pasteurized kombucha on gut health, metabolism, and liver function in people who are overweight or obese. Participants will drink kombucha daily for a set period to see if it improves their health.
Castelo Branco, Castelo Branco DistrictAges 18–60 - NCT06809166RecruitingPhase 4
Contrave for weight loss in adults with obesity
This study tests whether a weight loss medication called Contrave can help adults with obesity lose weight by changing how their body uses energy and handles food. If you qualify, you will take Contrave and be monitored for several months.
Ottawa, OntarioAges 18–64 - NCT07515547Recruiting
How Obesity Affects the Body Over Time
This research study examines how excess weight impacts your body's health and function, both in the short term and long term. Researchers want to understand the physical changes that happen with obesity and how your body responds.
Montreal, QuebecAges 25–40 - NCT07703371Recruiting
Kodo millet porridge and its effect on gut health and metabolic syndrome
This study tests whether eating Kodo millet porridge every day for 12 weeks can improve gut health and reduce risk factors for metabolic syndrome (like being overweight). If you are between 20 and 60 years old, are overweight or obese, and are willing to eat the porridge daily without changing your diet or exercise, you may be able to join.
Mysore, KarnatakaAges 20–60 - NCT07258576Recruiting
Birth control vs. natural cycle: muscle response to exercise
This study compares how muscle protein responds to resistance exercise in women who use birth control pills versus those with natural menstrual cycles. Participants will do exercise sessions and have muscle samples taken to see how their bodies build protein.
Toronto, OntarioAges 18–40 - NCT07336797RecruitingPhase 2
Empagliflozin for weight and metabolism in HIV
This trial tests if empagliflozin, a diabetes medicine, can improve weight and metabolism in people with HIV who take dolutegravir and have a high body mass index (BMI). It may help reduce weight gain linked to HIV treatment.
CairoAges 18–65 - NCT05275608Recruiting
Low-carb diet effects in people with metabolic syndrome
This trial studies whether a very low-calorie, low-carb diet (VLCKD) can improve metabolic health in adults with metabolic syndrome, fatty liver, and type 2 diabetes. It may help lower blood sugar and improve related health markers if you fit their specific diabetes and liver/kidney criteria.
Novara, ItalyAges 25–65 - NCT06923163Recruiting
How exercise affects your body's metabolism
This study looks at how exercise changes your metabolism in people who are not very active. It may help you understand how physical activity can benefit your health.
Shenzhen, GuangdongAges 18–40 - NCT07747909Recruiting
Orlistat for metabolic and hormonal health in PCOS
This study tests whether the weight-loss drug orlistat can improve blood sugar, hormones, and other metabolic measures in women with polycystic ovary syndrome (PCOS). If you have PCOS and are overweight, this treatment might help with symptoms like irregular periods and excess hair growth.
Abbottābād, Khyber PakhtunkhwaAges 18–45 - NCT06536881Recruiting
Diet and gut health during breast cancer chemo
This study looks at how changing your diet during chemotherapy affects side effects and your body's energy use. It involves providing stool samples to study gut bacteria.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07252362Recruiting
American ginseng's effect on urine and blood
This study looks at how American ginseng affects people's urine and blood, using a special test called LCMS-based metabolic analysis. It's for healthy individuals to understand the body's response to the herb.
Hangzhou, ZhejiangAges 18–45 - NCT02216500Recruiting
Study ketogenic diet effects in people with epilepsy
This study looks at how a high-fat, low-carbohydrate ketogenic diet may change electrical activity in the brain and related body measurements in people with epilepsy. You may be asked to follow the diet and keep records so the researchers can compare changes over time.
Gainesville, FloridaAges Up to 50 years - NCT07460856Recruiting
Can Cranberries Improve Your Gut and Metabolic Health?
This study tests if eating cranberries can improve your gut health and metabolism. It’s for people who are overweight and have early signs of metabolic problems, like high blood sugar or high triglycerides.
Québec, QuebecAges 25–70 - NCT07707778Enrolling by invitationPhase 4
Tirzepatide for Weight and Aging in People with HIV
This trial tests whether a weight-loss medicine called tirzepatide can slow biological aging and improve metabolism in people with HIV who are already on effective treatment. It may help you reduce weight and possibly reverse some signs of aging.
TaipeiAges 18 years+ - NCT05499702RecruitingPhase 2
Glucagon test after dieting in type 2 diabetes
This Phase 2 study tests how glucagon affects sugar and fat handling in the liver after a short period of calorie restriction. It may help researchers understand metabolic changes in people with type 2 diabetes and guide future treatments.
Rochester, MinnesotaAges 25–65
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Common questions
- Are there clinical trials for metabolic effects?
- Yes. Clin2 currently lists 201 recruiting metabolic effects studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic effects trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic effects trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.