Clinical trials
Microbiome clinical trials
Below are recruiting microbiome clinical trials, each written for real people, not researchers. We’re tracking 350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07143981Recruiting
Fecal transplant for anorexia nervosa
This trial tests whether taking fecal microbiome transplant (FMT) capsules can help people with anorexia nervosa. FMT uses processed stool from healthy donors to improve gut bacteria, which might support weight restoration and overall health.
London, OntarioAges 16–35 - NCT07144826RecruitingEarly Phase 1
Probiotic for Gut and Vaginal Health in Ovarian Cancer Chemotherapy
This trial tests whether taking a probiotic supplement can help balance the bacteria in your gut and vagina while you undergo chemotherapy for advanced ovarian cancer. It aims to see if this could improve your treatment experience or outcomes.
Columbus, OhioAges 18 years+ - NCT07162337Recruiting
Diet education to lower colon cancer risk after polyp removal
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
Boston, MassachusettsAges 18–80 - NCT07169019RecruitingEarly Phase 1
Probiotics and methotrexate for early psoriasis
This pilot study tests whether adding probiotics to standard methotrexate treatment improves symptoms in people newly diagnosed with chronic plaque psoriasis. It aims to see how the gut microbiome affects treatment response.
AlexandriaAges 18 years+ - NCT07173062Recruiting
Algae supplement for heart health and gut bacteria
This study tests whether a supplement made from algae can help improve markers of heart health and affect the bacteria in your gut. It is for people age 50 and older who already have a condition like heart disease, kidney disease, or diabetes.
PortoAges 50 years+ - NCT07186465RecruitingPhase 4
Preventing repeat bladder infections in postmenopausal women
This trial tests two approaches to prevent repeat bladder infections in postmenopausal women: a daily antibiotic pill or a vaginal tablet containing healthy bacteria and estrogen. The goal is to see which method works better over 6 months.
Bangkok, Phayatai RatchathewiAges 40 years+ - NCT07194551Recruiting
Checking uterine cancer risk in Lynch syndrome with home sampling
This study is testing a new way to check for uterine cancer risk in people with Lynch syndrome. You would collect a vaginal sample yourself at home and fill out a health questionnaire, which may help catch warning signs early.
Vancouver, British ColumbiaAges 30 years+ - NCT07195006Recruiting
Malnutrition in pregnancy and child growth study
This study looks at how nutrition during pregnancy affects the health of mothers and babies, including gut health and growth. It compares women with low nutrition to those with healthy nutrition.
HarareAges 18 years+ - NCT07212400Recruiting
Stool donor study: dairy phages, antibiotics, and gut bacteria
This study collects stool samples from healthy adults to see how dairy phages and antibiotics affect gut bacteria. It helps researchers understand how our diet and medicines interact with the microbiome.
Jouy-en-JosasAges 18–60 - NCT07218640Recruiting
Stool sampling study with chia seeds for adults
This trial asks adults to eat chia seeds and provide stool samples several times a week. Researchers want to learn more about digestion and gut health by studying the samples.
Ambler, PennsylvaniaAges 18–50 - NCT07225153Recruiting
Goat milk formula vs. undiluted goat milk for infant growth
This trial tests whether a goat milk-based formula helps infants who cannot breastfeed grow as well as those who drink undiluted goat milk. It focuses on babies living in the Matiari District whose families have access to goat milk.
Matiāri, SindhAges 2 months–2 months - NCT07236125Recruiting
Nitrate-rich foods and mouth bacteria in children with high blood pressure
This study looks at how eating nitrate-rich vegetables (like spinach and beets) might affect the helpful bacteria in your child's mouth and their blood pressure. It's for children ages 10 to 18 who have primary hypertension (high blood pressure not caused by another condition) and are otherwise healthy.
Istanbul, FatihAges 10–18 - NCT07250100Recruiting
Study of gut bacteria in pancreatic cancer and precancer
This study looks at the bacteria living in your gut and pancreas to understand how they might affect pancreatic cancer and precancerous changes. It is for people who are already scheduled for an endoscopic procedure to look at or treat a pancreatic lesion.
Herlev, Capital RegionAges 18 years+ - NCT06538415Recruiting
Can peas and beans improve your skin health?
This study tests whether adding more peas, beans, and lentils (polyphenol-rich pulses) to your daily diet can improve your skin health by changing the natural bacteria living on your skin.
Gainesville, FloridaAges 45–65 - NCT06504160RecruitingPhase 1
Testing a bacteria cream for eczema (TIME-2)
This study tests whether a cream made from a friendly skin bacteria (Staphylococcus hominis) can help treat eczema. Eligible participants will apply the cream to eczema patches on their arms, legs, or trunk for several weeks.
San Diego, CaliforniaAges 6 years+ - NCT07446205Recruiting
Poi for Mama: a study to reduce gestational diabetes risk
This pilot study tests whether eating poi (a traditional Hawaiian food made from taro) can improve the health of your gut bacteria and lower the risk of gestational diabetes during pregnancy. It is open to pregnant women who live on the windward side of O'ahu and are in their second trimester.
Honolulu, HawaiiAges 18 years+ - NCT07255430Recruiting
Airway bacteria study for children with PBB
This study looks at the bacteria in the airways of children with Protracted Bacterial Bronchitis (PBB), a long-lasting cough caused by bacteria. It aims to understand how these bacteria affect the condition, which could lead to better treatments.
EdegemAges Up to 5 years - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+ - NCT07308808RecruitingEarly Phase 1
Safety of a live bacteria solution for bladder infections
This trial tests if putting a live bacteria called Lactobacillus crispatus into the bladder is safe for people with spinal cord injury and neurogenic lower urinary tract dysfunction. It may help prevent urinary tract infections without antibiotics.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07316465Recruiting
Tracking immune markers in newborns at risk for eczema
This study follows newborns for two years to see how their immune system develops, especially if they have a family history of eczema, asthma, or hay fever. Researchers want to learn if certain immune markers appear early in babies who later develop eczema.
Jette, Brussels CapitalAges 1 hour–2 years - NCT07329595Recruiting
Tracking gut bacteria changes after severe burns
This study looks at how severe burns change the bacteria in your gut and your immune system. It will track these changes to better understand recovery and find new ways to help healing.
Debrecen, Hajdú-BiharAges 18–65 - NCT07351175Recruiting
Can a special cheese lower cholesterol by changing gut bacteria?
This study tests whether eating a type of aged cheese can help lower cholesterol by affecting the good bacteria in your gut. It is for people who regularly eat cheese, have slightly high cholesterol, and are generally healthy.
ReadingAges 18–65 - NCT02061306Recruiting
Study of gut microbes and genetics in infant celiac risk
This study looks at how gut bacteria, diet, and family background may relate to celiac disease risk in very young infants. It may help researchers understand why celiac disease happens and how it could be prevented or detected earlier.
Boston, MassachusettsAges Up to 6 months - NCT02779478Recruiting
Studying lung bacteria in people with NTM bronchiectasis
This study looks at the community of tiny organisms in the lungs (the lung microbiome) in people with bronchiectasis caused by NTM (non-tuberculous mycobacteria). It compares people with positive NTM cultures to people without, to better understand what’s going on in the lungs and why symptoms may differ.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for microbiome?
- Yes. Clin2 currently lists 350 recruiting microbiome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.