Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 376 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07333482Recruiting
Flourish: How gut bacteria grow in C-section babies
This study looks at the gut bacteria of infants born by C-section. Researchers want to learn how the microbiome develops in healthy babies who have not taken probiotics.
Austin, TexasAges birth–3 months - NCT07329595Recruiting
Tracking gut bacteria changes after severe burns
This study looks at how severe burns change the bacteria in your gut and your immune system. It will track these changes to better understand recovery and find new ways to help healing.
Debrecen, Hajdú-BiharAges 18–65 - NCT05251389RecruitingPhase 1/Phase 2
Fecal microbiome transplant after anti-PD-1 melanoma not working
This trial tests whether a fecal microbiome transplant (FMT) can help your body respond better to anti-PD-1 immunotherapy in advanced skin melanoma. It is for people whose melanoma has progressed despite anti-PD-1 treatment.
AmsterdamAges 18 years+ - NCT05516472RecruitingEarly Phase 1
Fecal transplant study for people with frequent kidney stones
This trial tests whether transplanting donated stool microbiome (fecal microbiota transplantation) can change gut bacteria and help reduce harm from frequent kidney stones. You would provide urine and stool samples and have follow-up checks to watch for side effects.
Park City, UtahAges 18–69 - NCT07320287Recruiting
Probiotics for babies born by C-section
This trial tests whether a multi-strain probiotic supplement can help with growth, digestion, and gut health in healthy full-term babies who were born by C-section.
HanoiAges birth–1 day - NCT07313007Recruiting
Gut bacteria chemicals in fatty liver disease
This study looks at whether the natural chemicals made by your gut bacteria from the food you eat could affect liver fat and health. If you have MASLD (a fatty liver condition), researchers want to measure these gut-produced substances to better understand the disease.
Pierre-BéniteAges 18–80 - NCT07306988RecruitingPhase 4
Treating H. pylori to improve metabolic syndrome
This trial tests whether treating H. pylori infection can help improve metabolic syndrome (a group of conditions like high blood sugar, abnormal cholesterol, and high blood pressure). It aims to understand how treatment changes your gut bacteria and overall health.
Nanjing, JiangsuAges 18–65 - NCT07300553RecruitingPhase 2
Gut bacteria and energy metabolism in health and IBD
This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.
ParisAges 18–50 - NCT04853212Recruiting
Study gut microbiome differences in people with spondyloarthritis
This study looks at whether changes in the gut bacteria (called microbiome dysbiosis) are linked to spondyloarthritis. It compares people with the condition to people without it who are already planning a digestive scope for another reason.
Boulogne-BillancourtAges 18 years+ - NCT07287306Recruiting
Probiotic study on gut health in healthy adults
This trial tests two probiotics, BLa80 and LRa05, to see how they affect the gut's natural bacteria and related substances. It may help understand how these probiotics support overall health.
Guangzhou, GuangdongAges 18–60 - NCT07283328Recruiting
Methionine and Gut Bacteria Study in Healthy Adults
This study looks at how a diet low in methionine (a protein building block) affects the bacteria in your gut.
Montreal, QuebecAges 20–50 - NCT05077618Recruiting
Teeth bacteria study in seniors with and without Alzheimer’s
This study looks at the bacteria in the mouth (periodontal microbiota) to see whether they differ between seniors with Alzheimer’s disease and seniors without it. You may be asked for a sample from your gums/teeth and background health information.
Nice, CHU de NICEAges 18–90 - NCT06291350Recruiting
Mouth bacteria in gum disease with blistering condition
This study looks at the bacteria in the mouth and gut of people with a blistering gum condition (mucous membrane pemphigoid) and gum disease. It aims to understand if certain bacteria are linked to the disease, which could lead to better treatments.
NiceAges 18 years+ - NCT06423508Recruiting
Testing stool storage methods and gut bacteria differences
This trial will study how different storage methods affect stool samples for gut bacteria analysis. It aims to understand differences in gut bacteria between people over time. Participation involves providing stool samples.
Vienna, State of ViennaAges 18–70 - NCT07264998Recruiting
Gut bacteria study in breast cancer patients on Abemaciclib
This study looks at how gut bacteria changes in people taking Abemaciclib (a breast cancer drug) and whether that relates to diarrhea. It may help find ways to prevent or manage this side effect.
Wuhan, HubeiAges 18–75 - NCT07264985Recruiting
Gut bacteria and diarrhea in breast cancer patients on pyrotinib
This study looks at how gut bacteria relate to diarrhea in breast cancer patients who are taking a drug called pyrotinib. By understanding this link, doctors hope to better manage side effects in the future.
Wuhan, HubeiAges 18–75 - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT06562842Recruiting
Exercise, Gut Health, and Type 2 Diabetes Study
This study looks at how exercise affects gut bacteria in people with type 2 diabetes. It may help explain why physical activity improves diabetes control.
TrikalaAges 45–65 - NCT07253402Recruiting
Microbiota-guided radiation therapy for head and neck cancer
This trial is testing a new way to use radiation therapy for head and neck cancer by also looking at the bacteria in your mouth and gut. The goal is to see if adjusting the treatment based on your bacteria can improve outcomes and reduce side effects.
Milan, MilanAges 18 years+ - NCT07250100Recruiting
Study of gut bacteria in pancreatic cancer and precancer
This study looks at the bacteria living in your gut and pancreas to understand how they might affect pancreatic cancer and precancerous changes. It is for people who are already scheduled for an endoscopic procedure to look at or treat a pancreatic lesion.
Herlev, Capital RegionAges 18 years+ - NCT07257913Recruiting
How dairy in food guide affects gut health
This study looks at how adding dairy products to the Canadian Food Guide affects the health of your gut. If you have a larger waistline but no major health issues or food allergies, this trial may help you learn more about your digestion.
Québec, QuebecAges 40–65 - NCT07252427Recruiting
Gut bacteria in IBD with or without depression
This study looks at how the bacteria in your gut (gut microbiome) may differ between people with IBD who also have depression and those who don't. It aims to help understand the link between gut health and mood.
Jinan, ShandongAges 18 years+ - NCT07247838Recruiting
Gut bacteria changes in first-time stroke patients
This study looks at how gut bacteria change right after a first-time ischemic stroke. It aims to understand if these changes are linked to recovery or other health factors.
Nantong, JiangsuAges 18 years+ - NCT06546020Recruiting
Haskap berries for gut and metabolic health
This study tests whether a berry called Haskap can improve your gut health and how that might affect your overall health. Researchers are looking for people with and without certain metabolic risk factors to see who benefits most from adding these berries to their diet.
Bozeman, MontanaAges 35–65
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 376 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.