Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 376 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07439640Recruiting
PEG laxatives for bowel prep and gut health after gallbladder removal
This study looks at how a common bowel prep medicine (PEG laxatives) affects gut bacteria in people who have had their gallbladder removed compared to those who still have one. It involves collecting stool samples before and after a colonoscopy to track changes over time.
Wuhan, HubeiAges 18–65 - NCT07429864Recruiting
Bulevirtide for hepatitis D: bile acids and gut bacteria
This study looks at how Bulevirtide, a treatment for hepatitis D, affects bile acids and gut bacteria. It may help patients with chronic HDV and stable liver disease who are already on HBV therapy.
RomaAges 18 years+ - NCT07417085Recruiting
Study of gut bacteria in children with brain tumors
This study looks at how gut bacteria (the microbiome) may differ in children with brain tumors. Researchers will collect samples before and after surgery to understand the connection between gut health and brain tumors.
Florence, FirenzeAges 3–18 - NCT07416760Recruiting
Gut bacteria study after intestinal surgery
This study looks at how gut bacteria change after surgery to reconnect the intestines (anastomosis). It may help doctors understand complications and improve recovery.
MadridAges 18 years+ - NCT05524649Recruiting
Probiotics for healthy newborns’ poop bacteria balance
This study looks at whether giving probiotics to healthy newborns changes the bacteria in their stool. It may help researchers understand early gut health, but it is only for babies who meet specific health and timing requirements.
Alcaldía Coyoacán, PueblaAges 1 day–3 months - NCT06265740Recruiting
Using vaginal bacteria to predict early labor
This study is testing a new way to predict early labor by looking at the bacteria in the vagina. If you are pregnant and in the hospital for possible early labor or a water break, a vaginal swab could help doctors understand why this happens.
Clermont-FerrandAges 18 years+ - NCT07408479Recruiting
How starch digestion affects blood sugar and health in insulin resistance
This trial studies how different types of starch (carbohydrates) affect blood sugar control, inflammation, and gut health in people with insulin resistance. You may benefit if you are overweight, have insulin resistance, and are willing to follow a specific diet for 2 months.
LyonAges 18–75 - NCT07381374Recruiting
Fecal transplant for children with autism
This trial tests whether fecal microbiota transplantation can help children with moderate-to-severe autism. It involves giving healthy donor bacteria to improve gut health and possibly autism symptoms.
Shenzhen, GuangdongAges 3–16 - NCT06405113RecruitingPhase 2
Fecal transplant, chemo, and immunotherapy for advanced stomach cancer
This trial tests a combination of fecal microbiota transplant (FMT), chemotherapy (SOX), and an immunotherapy drug (Sintilimab) as a first treatment for advanced stomach or gastroesophageal junction cancer that cannot be removed by surgery. The goal is to see if this combination can shrink tumors and improve outcomes.
ChangzhouAges 18–80 - NCT07385807Recruiting
Gut health and pregnancy in inflammatory bowel disease
This study looks at gut health in pregnant women with and without inflammatory bowel disease (IBD). It tracks a protein called calprotectin in stool samples, along with diet and baby health, to learn how IBD affects pregnancy and infant development.
Vancouver, British ColumbiaAges 19 years+ - NCT06837194Recruiting
Stool transplant with feeding tube nutrition for dropped stomach
This study tests whether a combination of a stool transplant (washed microbiota transplantation) plus liquid nutrition through a feeding tube can help people with gastroptosis who are also malnourished. The goal is to improve stomach function and nutrition.
Nanjing, JangsuAges 18–100 - NCT06837272Recruiting
Gut health and brain health in Alzheimer's disease
This study looks at how the bacteria in your gut might be connected to memory and thinking problems in Alzheimer's disease. It may help us understand if changes in the gut can affect brain health.
Jining, ShandongAges 60–80 - NCT06146608Recruiting
Iron, gut bacteria, and how the body absorbs iron
This study looks at how different types of iron in food affect your gut bacteria and how well your body absorbs iron. It aims to understand the connection between diet, gut health, and iron levels in healthy adults.
Ithaca, New YorkAges 18–40 - NCT07374094Recruiting
Understanding C. difficile infection and treatment effects
This study is tracking patients with a confirmed C. difficile infection to understand how the body responds and how treatments work. You may be asked to do follow-up visits for up to 5 years.
UmeåAges 18 years+ - NCT05473793Recruiting
Dried vegetables study for constipation and gut bacteria
This study tests whether eating a dried vegetable can improve bowel habits and change gut bacteria. It may help people who feel their bowel function is not working well and have hard or infrequent stools.
Wageningen, GelderlandAges 20–80 - NCT05623007Recruiting
Diet and gut bacteria study for vaccinated teens with COVID
This trial tests whether changing diet can shift gut bacteria in overweight or obese teens after COVID-19 vaccination. The goal is to see if dietary changes can affect health markers related to the gut and immune system.
Jakarta Pusat, DKI JakartaAges 12–17 - NCT07363551Recruiting
Omega-3 for depression in young people
This trial tests if omega-3 fatty acid supplements can improve depression in young people by reducing inflammation and changing gut bacteria. You may be eligible if you are a young person with a current major depressive episode.
Taichung, TaichungAges 13–18 - NCT07369830Recruiting
Probiotics for bowel function after rectal cancer surgery
This trial tests whether taking a probiotic supplement (Clostridium butyricum) can improve gut health and bowel function after surgery for very low rectal cancer. It may help patients who have a temporary ileostomy and are planning to have it reversed within 6 months.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07365514RecruitingPhase 1
Blackcurrants study for bone health in postmenopausal women
This trial tests if taking a blackcurrant supplement can help maintain bone density and reduce osteoporosis risk in postmenopausal women. You will take daily capsules and provide blood, stool, and bone scan samples over the study period.
Storrs, ConnecticutAges 45–70 - NCT07363304Recruiting
How ETI therapy affects body and gut in cystic fibrosis
This study looks at how the triple combination therapy (elexacaftor/tezacaftor/ivacaftor, or ETI) affects your body's metabolism, epigenetics, and gut bacteria in people with cystic fibrosis. It aims to understand the broader health benefits of this treatment.
Bari, BariAges 2 years+ - NCT04970446RecruitingPhase 1/Phase 2
Fecal transplant to restore gut microbes in Crohn’s
This Phase 1/2 study tests whether a fecal microbiome transplant (FMT) can reduce active inflammation in people with Crohn’s disease. It’s designed for people who currently have signs of active bowel inflammation and can attend regular procedure visits.
Melbourne, VictoriaAges 18–70 - NCT07342621Recruiting
Testing a special formula for babies with cow's milk allergy
This study tests whether a special formula with added prebiotics, probiotics, and a human milk nutrient helps manage symptoms in infants with cow's milk protein allergy. If your baby is starting a hypoallergenic formula for the first time, this trial may be an option.
Valencia, ValenciaAges Up to 10 months - NCT07334210Recruiting
Gut bacteria in sarcopenia and probiotic development
This study looks at gut bacteria differences between older adults with muscle loss (sarcopenia), healthy older adults, and younger adults. Results may help develop probiotics to support muscle health.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 376 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.