Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 376 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT06845527Recruiting
Gut bacteria testing in a clinic study
This study looks at people who visit a special gut bacteria clinic. It aims to learn more about their health by testing their gut bacteria as part of regular care.
Rome, RMAges 18 years+ - NCT06828159Recruiting
Can wild blueberries improve joint health?
This study tests whether eating wild blueberries can improve joint health in people with arthritis. You would eat blueberries or a placebo daily for several weeks to see if they help with pain and stiffness.
Oklahoma City, OklahomaAges 40–75 - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT05946083RecruitingPhase 2
Study links binge drinking, gut bacteria, and brain function
This Phase 2 study looks at how binge drinking may change gut bacteria and how your brain works. You may qualify if you’re a Portuguese-speaking student and your drinking pattern and health history match the study rules.
Braga, Gualtar, BragaAges 18–23 - NCT06805994RecruitingPhase 1
Restoring infant nose bacteria after staph treatment
This study tests whether giving a nasal spray of healthy bacteria to infants can restore good germs in the nose after they receive mupirocin ointment to treat Staph aureus. It aims to bring back a healthy nasal microbiome.
Baltimore, MarylandAges birth–60 years - NCT06801184Recruiting
Gut bacteria study for constipation-predominant IBS with methane
This study looks at the gut bacteria in people with irritable bowel syndrome (IBS) who have constipation and produce high levels of methane gas. It aims to understand how methane relates to symptoms and may guide future treatments.
LyonAges 18 years+ - NCT04792320Recruiting
Probiotics and fiber for kidney disease with leg artery blockage
This study tests whether an oral absorbent plus probiotics can improve gut health and circulation in people who have chronic kidney disease and symptomatic peripheral artery disease (PAD). It will also track changes in blood markers and how well blood vessels function.
TaipeiAges 20 years+ - NCT06781229Recruiting
Gum bacteria in people preparing for weight loss surgery
This trial looks at the bacteria in the mouths of people with a BMI of 30 or higher who are scheduled for weight-loss surgery. The goal is to understand how gum health and body weight are connected.
ToulouseAges 18 years+ - NCT06754319Recruiting
Gut bacteria and brain connection in child OCD
This study looks at how the bacteria in your gut might affect OCD in children and teens. It tests a possible link between your gut, brain, and OCD symptoms.
Shanghai, Shanghai MunicipalityAges 7–17 - NCT06747611RecruitingPhase 2
Gut bacteria transplant for alopecia areata
This study tests whether transplanting healthy gut bacteria can help people with moderate to severe alopecia areata regrow hair. You will take antibiotics to prepare your gut, then receive the transplant through a colonoscopy or capsules.
Minneapolis, MinnesotaAges 18–75 - NCT06746220Recruiting
Effect of activity and probiotics on body and health in women
This study looks at how adding physical activity and/or probiotics might affect your body composition and health. It is for women who are students at the University of Orléans and do not already exercise regularly.
OrléansAges 18 years+ - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65 - NCT06551272RecruitingPhase 2
Gut bacteria change to help immunotherapy for liver cancer
This trial tests whether changing the bacteria in your gut (with a probiotic) can help your current immunotherapy work better if your liver cancer has been growing. It's for people with advanced liver cancer who will continue their same immunotherapy despite the cancer progressing.
BobignyAges 18 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT06691100Recruiting
How one workout changes gut bugs in women
This study looks at how a single workout changes the bacteria in your gut. It compares women who are very fit with women who don't exercise much, and includes women with different body types.
Washington D.C., District of ColumbiaAges 21–40 - NCT06692361Recruiting
Gut bacteria transplant for depression not helped by escitalopram
This trial tests whether transplanting healthy gut bacteria (fecal microbiota) can help people with depression that does not respond well to the antidepressant escitalopram. You will first take escitalopram for 2 weeks, and if it doesn't help enough, you may receive either the real transplant or a placebo capsule.
Wuhu, AnhuiAges 18–65 - NCT06645535Enrolling by invitation
Gut Bacteria and Blood Substances in Stiff Heart Failure
This study looks at how bacteria in your gut and certain substances in your blood relate to a type of heart failure called HFpEF (where the heart is stiff and doesn't relax well). It may help doctors understand the condition better and find new ways to treat it.
Naning, JiangsuAges 18 years+ - NCT06623461RecruitingPhase 2
Fecal transplant with immunotherapy for advanced melanoma
This trial tests if giving a special capsule of donated bacteria (fecal transplant) alongside standard immunotherapy helps shrink tumors in people with advanced melanoma. It aims to see if adding the bacteria can make the immune therapy work better.
Abbotsford British Columbia, British ColumbiaAges 18 years+ - NCT06631586RecruitingPhase 2
Microbiota transplant for Crohn's disease
This study tests if a standardized fecal transplant is safe and helpful for adults with moderately to severely active Crohn's disease who are already on maintenance therapy. The goal is to see if this treatment can reduce inflammation in the digestive tract.
Minneapolis, MinnesotaAges 18–89 - NCT05695261RecruitingPhase 2
Oral microbiome capsules for peanut allergy in teens
This Phase 2 study tests whether taking capsules made from donor gut microbes is safe and can reduce allergic reactions to peanuts. It involves peanut allergy testing and close follow-up with stool samples and check-ins.
Boston, MassachusettsAges 12–17 - NCT06603519Enrolling by invitation
Can a diet reduce inflammation after a colonoscopy?
This study tests whether a special diet can help reduce inflammation and improve gut health after a colonoscopy. It is for people who are getting a repeat colonoscopy because they've had polyps before.
San Diego, CaliforniaAges 18 years+ - NCT06609980RecruitingPhase 1
Fecal transplant to restore gut health in infants
This study tests whether giving a baby’s own stool back to them (after it was stored before antibiotics) can help restore healthy gut bacteria. It’s for healthy infants and toddlers up to 4 years old who haven’t recently taken antibiotics.
New Brunswick, New JerseyAges 1 month–4 years - NCT06451913RecruitingPhase 4
Probiotic for gut health during Lyme disease antibiotics
This trial tests if a probiotic (Saccharomyces boulardii) can help maintain healthy gut bacteria while you take antibiotics for the early skin rash of Lyme disease (erythema migrans). You'll take amoxicillin for 14 days, plus either the probiotic or a placebo.
LjubljanaAges 18 years+
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 376 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.