Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 408 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06641778Recruiting
Fecal transplant for drug-resistant Klebsiella pneumonia
This trial tests whether transplanting healthy donor stool into the lungs can help treat a severe pneumonia caused by a bacteria that is resistant to many antibiotics. It may offer a new option for people whose infection is not responding to standard treatments.
Wuhan, HubeiAges 18–75 - NCT07578103Recruiting
Dairy vs Plant-based Yogurt for Weight and Bone Health
This study compares how dairy yogurt and plant-based yogurt affect weight, body composition, bone strength, and gut bacteria in postmenopausal women. It may help identify which type of yogurt is better for overall health during this life stage.
Québec, QuebecAges 40 years+ - NCT07190183Recruiting
Washed microbiota transplant for food intolerance
This trial tests a treatment called washed microbiota transplantation for people with food intolerance. It may help reduce symptoms by restoring healthy gut bacteria.
Nanjing, JiangsuAges Any age - NCT05664113RecruitingPhase 1
Fecal transplant for gut problems after stem cell transplant
This study tests whether transplanting healthy donor stool into the gut can help children and young adults with ongoing digestive issues after a stem cell transplant. It may improve symptoms like diarrhea or the need for feeding tubes.
Memphis, TennesseeAges Up to 22 years - NCT03325855Recruiting
Fecal transplant registry for patients and donors
This study is a national “registry” that collects information from people who get fecal microbiota transplant (a stool-based treatment) and from people who donate stool. It helps researchers understand who receives these treatments and how they do over time.
Phoenix, ArizonaAges Any age - NCT03562741Recruiting
Tracking outcomes of fecal transplant for repeated C. difficile
This study looks at how fecal microbiota transplantation (a transplant of healthy gut bacteria) works for people who get C. difficile infection repeatedly. It also focuses on collecting follow-up information to better understand which patients benefit and how.
Worcester, MassachusettsAges 16 years+ - NCT03764748RecruitingPhase 1
Washed stool transplant for Tourette syndrome in kids
This Phase 1 study tests whether a “washed” stool microbiota transplant can reduce Tourette syndrome tics in children. It aims to see if changing gut bacteria is safe and may improve tic severity.
Nanjing, JiangsuAges 6–17 - NCT03895593Recruiting
Fecal transplant for stubborn intestinal infections
This study looks at “rescue” fecal microbiota transplantation (FMT), which replaces gut microbes using stool from a screened donor, for intestinal infections that have not improved with standard care. It may help patients whose infection keeps coming back or doesn’t respond to treatment.
Nanjing, JiangsuAges Any age - NCT03928431Recruiting
Restore gut bacteria in newborns using special microbiome samples
This study looks at whether restoring a newborn’s gut bacteria (microbiome) can improve early health. Babies are treated based on the birth conditions, especially whether delivery was vaginal or by C-section.
Stockholm, Stockholm CountyAges 5 minutes–15 minutes - NCT03983473Recruiting
Testing stool samples to find gut bacteria markers in inflammatory arthritis
This study looks at stool (poop) samples to see whether gut bacteria patterns can help identify certain inflammatory arthritis conditions in people who have Crohn’s disease or axial spondyloarthritis. It’s mainly about matching stool “biomarkers” to diagnoses, which may help doctors recognize these conditions more accurately in the future.
Nancy, LorraineAges 18 years+ - NCT05548452RecruitingPhase 1/Phase 2
Microbiota transplant for advanced liver disease from alcohol
This trial tests whether giving a healthy mix of gut bacteria (an intestinal microbiota transplant) can improve outcomes in people with advanced liver disease caused by ongoing alcohol use. It may help rebalance the gut and support liver health, but participation depends on strict safety and diagnosis criteria.
Richmond, VirginiaAges 18 years+ - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT04038619RecruitingPhase 1
Fecal transplant for immune-therapy diarrhea or bowel inflammation
This early-phase study tests whether stool/fecal microbiota transplant (a fecal transplant) can help people who develop significant diarrhea or colitis after immune-checkpoint therapy. It aims to reduce bowel inflammation and improve symptoms, while carefully checking for infections.
Houston, TexasAges 18 years+ - NCT04203303Recruiting
Study how your gut microbes affect health and disease
This study looks at how the bacteria (microbes) living in and on your body relate to health and disease. It may help researchers understand what changes in these microbes mean for future treatments.
Rochester, MinnesotaAges 18 years+ - NCT04447742Recruiting
Study of how healthy babies’ gut microbes develop from birth
This study follows pregnant people from about 20 weeks until delivery, to understand how gut microbes (tiny organisms in the intestines) develop in healthy babies. It may help researchers learn how early-life gut development affects health later on.
BernAges 18–45 - NCT04637438Recruiting
Fecal transplant for Crohn’s around the small and large bowel
This trial studies fecal microbiota transplantation (a transplant of beneficial gut bacteria from a donor) to help people with Crohn’s disease that is causing narrowing (strictures) and/or abnormal tunnels (fistulas) and who need bowel surgery. You may qualify if you’re an adult, planning ileal/ileocecal surgery, and can complete the colonoscopy while not on certain gut-altering medicines.
TampereAges 18–120 - NCT04721041Recruiting
Fecal microbiota transplant for gut side effects after cancer treatment
This trial tests a treatment called “washed microbiota transplant,” which transfers healthy gut bacteria to help relieve intestinal problems that started after cancer therapy. You might benefit if you’re an adult with certain ongoing stomach or bowel symptoms after standard cancer treatment, and your body is stable enough for the procedure.
Nanjing, JiangsuAges 18 years+ - NCT04932577RecruitingPhase 2/Phase 3
Fecal transplant to treat complications of liver cirrhosis
This trial studies whether transferring healthy gut bacteria (from a donor sample) can improve outcomes for people with liver cirrhosis who have worsening complications. It may help by changing the gut microbiome, which can influence inflammation and liver health.
AarhusAges 18–75 - NCT04935684RecruitingPhase 2
Fecal transplant after bone marrow transplant to improve gut health
This Phase 2 study tests whether a fecal microbiota transplant (a processed transplant of gut bacteria) after an allogeneic bone marrow transplant is safe and helpful. Participants may benefit by improving recovery in the gut microbiome during the post-transplant period.
AmiensAges 18 years+ - NCT04997733RecruitingPhase 3
Stool transplant to maintain Crohn’s remission after stopping anti-TNF
This Phase 3 study tests whether transplanting stool bacteria can help people with Crohn’s stay in remission after they stop an anti-TNF medicine. It may help some patients who are currently doing well but need to come off anti-TNF treatment.
ParisAges 18–74 - NCT05006430RecruitingPhase 1/Phase 2
Fecal transplant study for severe alcoholic hepatitis safety
This trial tests whether fecal microbiota transplantation (a controlled transfer of stool bacteria) is safe in people with severe alcoholic hepatitis. It aims to see if the treatment is tolerable and what risks may come with it, in addition to watching how liver illness changes.
Houston, TexasAges 18–75 - NCT05035342RecruitingPhase 3
Fecal transplant to clear resistant gut bacteria
This Phase 3 study tests whether a fecal microbiota transplant (FMT) can eliminate hard-to-treat bacteria in the gut, such as ESBL or carbapenem-resistant bacteria. If it works, it may reduce future infections and antibiotic-resistant illness.
ClichyAges 18–105 - NCT05170971Recruiting
Fecal transplant trial for worsening liver failure
This trial studies fecal microbiota transplantation (a transfer of healthy gut bacteria from a donor) to help people with worsening liver failure. It may help by changing gut bacteria, which can affect complications like confusion, fluid buildup, infections, and kidney problems.
Ningbo, ZhejiangAges 18–65 - NCT05266807RecruitingPhase 3
Capsule fecal transplant to prevent C. difficile coming back
This study tests whether taking a capsule form of fecal microbiota transplant (FMT) can help adults with their first C. difficile infection—or a first relapse—get better and reduce repeat episodes. Participants also take specific antibiotics for C. difficile as part of the study process.
Basel, BaselAges 18 years+
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 408 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.