Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 408 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05321758Recruiting
Stool transplant as first treatment for kids with Crohn’s
This study tests whether transferring healthy gut bacteria from stool into the colon can work as a first treatment for children newly diagnosed with mild-to-moderate Crohn’s disease. It may help reduce inflammation and improve symptoms, and it requires regular colonoscopy to monitor progress.
Wuhan, HubeiAges 2–16 - NCT05361785Recruiting
Fecal transplant to help IBS food sensitivity
This study tests whether transferring gut bacteria from a healthy donor to a participant can reduce irritable bowel syndrome (IBS) symptoms related to food sensitivity. You may be asked to follow a low-FODMAP diet and receive a fecal microbiota transplant if you meet the study’s safety and health requirements.
Helsinki, Helsinki and UusimaaAges 18–75 - NCT05439135Recruiting
Fecal microbiome transplant to treat malnutrition after GI surgery
This trial tests whether “washed microbiota transplant” (a treatment using processed gut bacteria) can improve malnutrition in adults who developed it after certain upper gut surgeries. It may help by restoring helpful gut bacteria, but you must meet several medical and safety checks.
Nanjing, JiangsuAges 18 years+ - NCT05502913RecruitingPhase 2
Fecal transplant plus cancer immunotherapy for lung cancer
This trial studies whether giving a fecal microbiota transplant (a stool-based sample from a carefully screened donor) alongside immune checkpoint inhibitors can improve outcomes in people with lung cancer. It aims to change the gut bacteria to help the immune system work better against the cancer.
BeershebaAges 18 years+ - NCT05605353Recruiting
Using gut bacteria to study pelvic cancers
This study looks at gut bacteria (and the chemicals they make) in people being treated for pelvic cancers. The goal is to understand what might be happening in the gut and how it could relate to pelvic cancer.
Aberdeen, ScotlandAges 16–99 - NCT05606523Recruiting
Test gut bacteria treatment for weight loss in pancreatic cancer
This study looks at how changing the gut microbiome (gut bacteria) may help people with pancreatic cancer regain strength and slow or reverse cancer-related weight loss (cachexia). It also studies gut bacteria differences in people with pancreatic cancer who are losing weight versus those whose weight is stable, and in healthy volunteers.
GenevaAges 18 years+ - NCT05739825Recruiting
Fecal transplant to change gut bacteria in C. difficile infection
This trial studies whether fecal microbiota transplantation (a procedure that transfers healthy stool bacteria) can change a person’s gut bacteria after repeated C. difficile infection. It may help reduce recurring infections by restoring a healthier balance of gut microbes.
RomaAges 18–90 - NCT05803993Recruiting
Fecal transplant to ease constipation in irritable bowel syndrome
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
RomaAges 18 years+ - NCT05803980Recruiting
Fecal transplant to ease IBS diarrhea symptoms
This study tests whether fecal microbiota transplantation (a stool-based treatment to change gut bacteria) can reduce symptoms of irritable bowel syndrome (IBS) that comes with diarrhea. You may be eligible if you’re an adult with diarrhea-predominant IBS and recent colonoscopy results that rule out other intestinal diseases.
RomaAges 18 years+ - NCT05829109RecruitingEarly Phase 1
Stool transplant for long-term inflamed pouch after surgery
This early-phase study tests fecal microbiota transplant (a stool-based treatment) to improve chronic pouchitis symptoms in adults after UC-related surgery. It may help by changing gut bacteria, especially for people who need ongoing antibiotics or keep having flare-ups.
New York, New YorkAges 18 years+ - NCT05862363Recruiting
Food and samples study in underweight pregnancy and indigestion
This study looks at how food support and sample testing might affect gut and stomach health in women who are underweight or have “functional dyspepsia,” including during pregnancy. It may help researchers learn whether this approach improves digestive symptoms and related health markers for mothers and babies.
Dhaka, Dhaka DivisionAges 18–35 - NCT05996016Recruiting
Gut and vaginal bacteria in HIV-positive women
This study looks at the types of bacteria living in the gut and vagina of women with HIV, including pregnant women. It aims to understand how these bacteria might affect health.
Beijing, Beijing MunicipalityAges 14 years+ - NCT06058520RecruitingEarly Phase 1
Capsule microbiome transplant for hidradenitis suppurativa
This trial tests whether taking capsules containing healthy gut bacteria (fecal microbiota transplant) can help treat hidradenitis suppurativa. You may qualify if you have HS and haven't taken antibiotics in the last 30 days.
Minneapolis, MinnesotaAges 18 years+ - NCT06144905Recruiting
Norwegian Gut Bacteria Study in Anorexia Nervosa
This study looks at gut bacteria in women with anorexia nervosa compared to healthy women. It aims to understand how gut health relates to the condition and recovery.
Ås, ÅsAges 16–50 - NCT06182293Recruiting
Mouth bacteria in early systemic sclerosis
This study looks at the bacteria in the mouth (periodontal microbiota) of people with early systemic sclerosis compared to those without the condition. It may help understand if there is a link between oral health and systemic sclerosis.
StrasbourgAges 18 years+ - NCT06192693RecruitingPhase 3
Fecal transplant to improve diabetes after weight loss surgery
This trial tests whether transferring healthy stool bacteria from a lean donor can help improve blood sugar control in people with type 2 diabetes who still have high blood sugar 1-5 years after weight loss surgery.
ParisAges 18–65 - NCT06215222Recruiting
Studying gut bacteria in IBS and digestive issues
This study uses a tiny capsule to collect samples from your small intestine to learn about gut bacteria in people with IBS or other functional gut disorders. It could help researchers understand what causes digestive symptoms.
Redwood City, CaliforniaAges 18–70 - NCT06218602RecruitingPhase 2
Fecal transplant for lymphoma patients getting CAR T therapy
This trial tests whether giving a fecal transplant (a stool enema from a healthy donor) can improve the response to CAR T-cell therapy in people with B-cell lymphoma. It may help by restoring healthy gut bacteria that are often wiped out by strong antibiotics.
Houston, TexasAges 18 years+ - NCT06228937Recruiting
Gut bacteria and lymphedema with repeated infections
This study looks at the bacteria in your gut and how they relate to lymphedema (swelling) and repeated skin infections in the affected limb. It compares people who have many infections with those who have none, to better understand why some get infections and others don't.
RomeAges 18–85 - NCT06286709RecruitingPhase 2
Fecal transplant for PSC and colitis
This trial tests whether a fecal (stool) transplant from a healthy donor can help people with both PSC and inflammatory bowel disease. It aims to see if the treatment can improve liver health and reduce inflammation. You must have early to moderate liver scarring and be on stable medications.
BirminghamAges 18 years+ - NCT06290258RecruitingPhase 1/Phase 2
Fecal transplant for autism with stomach issues
This study tests if transplanting healthy bacteria into the gut can help children and young adults with autism who also have stomach problems. It aims to improve both digestive and behavioral symptoms.
Taoyuan CityAges 7–30 - NCT05679622Recruiting
Stool transplant study for children with mild to moderate ulcerative colitis
This trial studies whether transferring healthy stool bacteria into the gut (fecal microbiota transplantation, or FMT) can improve symptoms in children with ulcerative colitis. It may help by changing gut bacteria, especially for children who are newly diagnosed or who didn’t respond to standard treatments.
WuhanAges 2–16 - NCT06376331RecruitingPhase 1
Washed gut bacteria transplant for ADHD
This trial tests whether transplanting specially cleaned gut bacteria from healthy donors can help children with ADHD. It aims to see if improving the balance of gut bacteria can reduce ADHD symptoms.
Nanjing, JiangsuAges 3–17 - NCT06447220Recruiting
Washed Microbiota Transplant for Malnutrition
This trial studies if a special, cleaned-up version of fecal transplant (called washed microbiota transplantation) helps treat malnutrition in adults. It is for people who have already had this transplant and have either lost a significant amount of weight or have a low body mass index (BMI).
Nanjing, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 408 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.