Clinical trials
Migraine Headache, With or Without Aura clinical trials
Below are recruiting migraine headache, with or without aura clinical trials, each written for real people, not researchers. We’re tracking 188 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04628429Recruiting
Study CGRP blocker effects on migraine and body nerve function
This study tests a CGRP-blocking antibody to see how it affects migraine symptoms and the body’s automatic (involuntary) nerve functions. It may help people with migraine who have already tried several preventive medicines.
ViennaAges 18–64 - NCT07573488Recruiting
Sleep, Stress, and Migraine: Observation and Training Study
This study explores how sleep and stress affect migraine headaches and tests whether improving sleep habits can help reduce migraines. You'll be observed and taught strategies over several months while researchers track your headaches and sleep patterns.
ZurichAges 18–65 - NCT07567300Recruiting
Understanding Pain Patterns in Migraine and Neck or Back Pain
This study explores how migraine headaches, neck pain, and lower back pain may share similar pain mechanisms in the body. Researchers will ask you questions to understand your pain patterns and help identify connections between these conditions.
Gaziantep, MerkezAges 18–65 - NCT06839118RecruitingPhase 3
Botox for headaches after head injury
This trial tests if Botox injections can reduce headache days in people with persistent headaches after a mild head injury. It may help if you have headaches at least 15 days a month.
Glostrup MunicipalityAges 18–80 - NCT07301008RecruitingPhase 4
Rimegepant to prevent predictable trigger-induced migraines
This trial tests whether a medication called rimegepant can prevent migraines when you take it before a known trigger (like exercise or stress). It is for people who get migraines often and can predict when one might happen.
McLean, VirginiaAges 18 years+ - NCT06882122Recruiting
Atogepant for episodic migraine: brain and body effects
This study tests a daily pill called atogepant to see how it affects the brain and body in people with episodic migraine. It may help if you have 8 to 14 migraine days a month and haven't tried CGRP treatments before.
Pavia, PAVIAAges 18–70 - NCT07233941Recruiting
Cognitive and psychological study in migraine patients
This study looks at thinking abilities and psychological factors in people with migraines. It aims to understand how migraine affects memory, attention, and emotions.
MilanAges 18–65 - NCT07136740Recruiting
Biofeedback for preventing tension headaches
This study tests whether a smartphone app that teaches you biofeedback (a way to relax muscles using sensors) can help prevent tension headaches. You will use the app at home to practice techniques and track your headaches.
NamsosAges 18 years+ - NCT07059546Recruiting
Studying sensitivity to adrenomedullin in chronic post-traumatic headache
This trial tests whether people with long-term headache after a mild head injury have an abnormal reaction to a substance called adrenomedullin, which may play a role in causing headaches. You will receive adrenomedullin and a placebo in separate sessions to see how your headache responds.
Glostrup MunicipalityAges 18–65 - NCT06967909Recruiting
Tai Chi vs. Acupuncture for Migraine Prevention
This study compares Tai Chi and acupuncture to see which is better at preventing migraines and improving brain health. If you are a Chinese woman in Hong Kong who gets migraines 2 to 14 days per month, you may be able to join.
Hung HomAges 18 years+ - NCT06428838Enrolling by invitationPhase 3
Add-on migraine treatment for emergency room visits
This study tests an add-on migraine medicine (eptinezumab) given in the emergency room to quickly relieve a migraine attack, in addition to the usual care. It aims to see if this approach reduces pain and prevents the migraine from coming back.
New Westminster, British ColumbiaAges 19–75 - NCT04965675RecruitingPhase 3
Eptinezumab for teens with chronic migraine
This trial tests eptinezumab, a preventive medicine, to reduce headache frequency in teens with chronic migraine. It may help your teen if they have frequent migraine days despite usual care.
New Haven, ConnecticutAges 12–17 - NCT06134791Recruiting
Comparing neck test results in cervicogenic headache patients
This study compares people with cervicogenic headache (headache from neck problems) to see if a simple neck test can tell them apart. It aims to help doctors diagnose this type of headache better.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07872943RecruitingPhase 4
Chinese herbal tablets for frequent tension-type headache
This study tests whether a Chinese herbal tablet called Zhixuan Analgesic can reduce headache frequency in adults with frequent tension-type headaches. Participants will take the tablets for a period and track their headache days.
Wuhan, HubeiAges 18–60 - NCT07841509Recruiting
Remote electrical neuromodulation for migraine and fibromyalgia
This study tests a wearable device that uses gentle electrical signals to reduce pain in people with migraine or fibromyalgia. It may help by changing how the brain processes pain signals.
Bridgewater, New JerseyAges 18 years+ - NCT07820280Recruiting
Neck mobilization for cervicogenic headache relief
This study compares two gentle neck therapy techniques to see which better reduces headaches that start from the neck. It aims to help people with neck-related headaches move better and feel less pain.
IslamabadAges 18–40 - NCT07816367RecruitingPhase 3
Elismetrep for treating migraine attacks
This study tests an investigational medicine called elismetrep (K-304) for treating migraine attacks quickly. If you have migraines, you take the medicine when a migraine starts and report how well it works.
Glendale, ArizonaAges 18–75 - NCT07776275Recruiting
Headache study comparing neck pain patients with healthy people
This study looks at physical differences between people with cervicogenic headache (a headache that starts in the neck), people with chronic neck pain without headache, and healthy controls. By comparing these groups, researchers hope to better understand what causes the headache and which physical features are specific to it.
Istanbul, SefaköyAges 25–60 - NCT07769255Recruiting
Nebulized dexmedetomidine for early chronic migraine
This trial tests whether a medicine called dexmedetomidine, given through a nebulizer (mist you breathe in), can help reduce the number of headache days and prevent migraines from becoming chronic. It is for people who have recently started having many headache days each month.
Banī SuwayfAges 18–55 - NCT07762690Enrolling by invitation
Neck rehabilitation for chronic migraine
This study tests a neck exercise program designed to improve neck function and reduce migraine symptoms. It may help people whose migraines are linked to neck problems.
Banī Suwayf, EgyptAges 18–55 - NCT07743255Enrolling by invitation
Preventing migraines in children with melatonin and propranolol
This study tests whether two common medicines, melatonin and propranolol, can help prevent migraines in children. If your child has frequent, disabling migraines, this treatment might reduce how often they occur and improve daily life.
Multan, Punjab ProvinceAges 5–15 - NCT07729462RecruitingPhase 3
Rimegepant for preventing chronic migraine
This study tests whether the medication rimegepant can help prevent chronic migraine in adults. It may be an option if you have frequent migraines and have not tried certain other preventive treatments.
Scottsdale, ArizonaAges 18 years+ - NCT06509503RecruitingPhase 4
Effect of birth control pills on migraine
This study tests how combined oral contraceptive pills affect migraine in women. It will compare people who take these pills with those using non-hormonal methods like an IUD, to see if the pills help or change the migraine pattern.
Kafr ash ShaykhAges 18–55 - NCT07694063Recruiting
Online yoga for frequent migraines
This trial tests if online Hatha yoga classes can help adults who have frequent migraines (but not daily). If you have migraines 8–14 days a month and are already on stable medication, this study may offer a gentle addition to your treatment.
Seville, SevillaAges 18–65
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Common questions
- Are there clinical trials for migraine headache, with or without aura?
- Yes. Clin2 currently lists 188 recruiting migraine headache, with or without aura studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine headache, with or without aura trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine headache, with or without aura trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.