Clinical trials
Migraine Headache, With or Without Aura clinical trials
Below are recruiting migraine headache, with or without aura clinical trials, each written for real people, not researchers. We’re tracking 188 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07360782Recruiting
Personalized nerve treatment for medication overuse headache
This trial tests a treatment called personalized pulsed radiofrequency, which uses gentle electrical pulses on a nerve at the back of your head to help reduce headaches caused by using too much pain medication. It is designed for people who have been diagnosed with Medication Overuse Headache and want a non-drug option.
AnkaraAges 18–65 - NCT07328685Recruiting
Body awareness therapy for migraine relief
This trial tests a gentle therapy called Basic Body Awareness Therapy to see if it helps reduce migraine attacks. It focuses on improving how you sense and move your body, which may ease migraine symptoms.
Antakya, HatayAges 18–55 - NCT07325513Recruiting
Brain stimulation for Gulf War-related pain
This study tests whether a type of brain stimulation (repeated transcranial magnetic stimulation, or rTMS) can help reduce headaches and body pain in veterans with Gulf War Illness. If you are a Gulf War veteran with ongoing moderate-to-severe pain, this trial could help find a new way to manage your symptoms.
San Diego, CaliforniaAges 18–65 - NCT07310290Recruiting
Study of Ubrogepant for Migraine During the Prodrome Phase
This study looks at how well the migraine medication ubrogepant works when taken during the early signs of a migraine (prodrome). It may help people who already use ubrogepant for their migraines.
Aliso Viejo, CaliforniaAges 18 years+ - NCT07307508Recruiting
Scalp block for headache after aneurysm bleeding
This trial tests if a scalp nerve block can better manage severe headaches after a brain aneurysm rupture. It is for patients who had an aneurysm treated with coiling in the intensive care unit.
DohaAges 18 years+ - NCT07310823Enrolling by invitation
Manual therapy for neck-related headaches
This study tests if manual therapy (hands-on treatment) can help people whose headaches start from neck problems. If you have headaches at least once a week and limited neck movement, this trial may be an option.
GizaAges 20–40 - NCT06875869Recruiting
Pressure techniques for cervicogenic headache
This trial compares two different pressure techniques (ischemic compression and the Jones technique) to see which better relieves head pain that starts from the neck (cervicogenic headache). It may help if you are an adult aged 25 to 35 with neck-related headaches and specific tender points in your muscles.
Bahawalpur, Punjab ProvinceAges 25–35 - NCT07304518RecruitingPhase 2
PRT-064040 nasal spray for migraine in adults
This trial tests a new nasal spray, PRT-064040, to see if it can help treat migraine attacks. It is for adults who have had migraines for at least a year and get 2 to 8 moderate to severe migraines per month.
Beijing, Beijing MunicipalityAges 18–75 - NCT07279623Recruiting
Nasal stimulation device for migraine prevention
This trial tests if a gentle nasal stimulation device can help prevent migraines. It is for adults with frequent migraines (at least 8 days per month).
StockholmAges 18–65 - NCT07170176Recruiting
PFO closure and migraine: can it help?
This trial tests if closing a common heart defect (PFO) can improve migraine symptoms and brain function. It compares people with migraine who get the closure procedure to those without migraine.
Luoyang, HenanAges 18–60 - NCT07168512Recruiting
Release technique and exercises for cervicogenic headache
This trial tests whether a gentle hands-on therapy called myofascial release, alone or with exercises, can improve the neck curve, sleep, and mood in people whose headaches come from a neck problem. If you have headaches that start from your neck, this might help you find relief.
Gaza, Gaza StripAges 20–55 - NCT05570149Recruiting
Study of eptinezumab in people with frequent migraine
This real-world study looks at how well eptinezumab (an antibody medicine for migraine prevention) works for people with frequent episodic or chronic migraine as they get usual care. You may be asked to share health information and treatment details to see what helps most in everyday life.
Roma, RMAges 18–75 - NCT06953622Recruiting
Migraine and PFO: A Follow-up Study
This study is for people who have migraines and a small hole in their heart called a patent foramen ovale (PFO). It will track your health over time to learn more about how these conditions are related.
BeijingAges Any age - NCT07163208Recruiting
Laser therapy for headache from neck problems
This trial tests if different types of low-level laser light can help reduce headaches caused by neck issues. It is a non-invasive treatment option for people whose headaches have lasted at least three months.
Lahore, Punjab ProvinceAges 18–65 - NCT07163559Enrolling by invitation
Coping skills program for migraine relief
This study tests a 6-month program that teaches coping skills to help manage migraine headaches. It may help you feel more in control of your symptoms.
Ankara, AltındağAges 18–65 - NCT07163416Recruiting
Italian migraine registry study for adults
This study tracks people with migraine to learn more about their condition and improve care. You may join if you have episodic or chronic migraine, with or without aura or medication overuse headaches.
Roma, RomaAges 18 years+ - NCT07093138RecruitingPhase 4
CBD cream for migraine attacks
This trial tests whether a cream made with cannabidiol (CBD) can help stop migraine attacks. It is for people aged 18 to 55 who have had migraines for at least a year and get 2 to 8 attacks per month.
TehranAges 18–55 - NCT06974617Recruiting
Nerve block vs. Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (sphenopalatine block) and Botox injections. It aims to see which one works better for reducing headache days.
CairoAges 18–65 - NCT07067112Recruiting
Studying immune cells in migraine blood
This study looks at blood samples from women with and without migraine to understand how certain immune cells (called regulatory T cells) might be involved. The goal is to learn more about what causes migraine, which could lead to better treatments.
Clermont-FerrandAges 18–50 - NCT07072910RecruitingPhase 2
Cabergoline for migraine prevention
This trial tests if a once-weekly medication called cabergoline can reduce how often you get migraine headaches. It is for adults who have between 4 and 14 migraine days per month.
Aarhus NAges 18 years+ - NCT07061847RecruitingPhase 2
Lidocaine infusion for severe chronic migraines
This trial tests if a lidocaine infusion into an artery in the head can reduce severe chronic daily headaches. It is for people who have tried multiple treatments without enough relief.
Great Neck, New YorkAges 18–75 - NCT07054801RecruitingPhase 2
Testing lidocaine and steroids for headache after bleeding stroke
This study tests whether giving two medicines (lidocaine and methylprednisolone) directly into the artery during a routine brain vessel procedure can help relieve headaches caused by a bleeding stroke. It may help find a new treatment for this type of headache.
San Francisco, CaliforniaAges 18 years+ - NCT07023926Recruiting
Acupuncture to prevent menstrual migraine
This study tests whether acupuncture can reduce the number of migraine headaches around your period. If you often get migraines with your menstrual cycle, this treatment might help prevent them.
Beijing, Beijing MunicipalityAges 18–45 - NCT06995729RecruitingPhase 1
Testing zavegepant nasal spray in children with migraines
This trial tests whether the medicine zavegepant (given as a nasal spray) is safe and works well for children aged 6 to 11 who have a history of migraines. If your child gets migraines, this study may help find a new treatment option.
Washington D.C., District of ColumbiaAges 6–11
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Common questions
- Are there clinical trials for migraine headache, with or without aura?
- Yes. Clin2 currently lists 188 recruiting migraine headache, with or without aura studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine headache, with or without aura trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine headache, with or without aura trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.