Clinical trials
Migraine Headache, With or Without Aura clinical trials
Below are recruiting migraine headache, with or without aura clinical trials, each written for real people, not researchers. We’re tracking 193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05125302RecruitingPhase 3
Ubrogepant for acute migraine relief in kids and teens
This study tests how safe ubrogepant is and whether it helps treat an individual migraine attack in children and teens. It focuses on measuring side effects and whether headaches improve 2 hours after taking the study medicine.
Huntsville, AlabamaAges 6–17 - NCT05524493Recruiting
Brain scans for migraine, visual snow, or epilepsy symptoms
This study uses a very strong MRI brain scanner to better understand conditions like migraine, visual snow, or epilepsy that don’t fully respond to treatment. You may be able to join if you meet specific diagnosis and safety requirements for the scanner.
ZurichAges 18–65 - NCT05570149Recruiting
Study of eptinezumab in people with frequent migraine
This real-world study looks at how well eptinezumab (an antibody medicine for migraine prevention) works for people with frequent episodic or chronic migraine as they get usual care. You may be asked to share health information and treatment details to see what helps most in everyday life.
Roma, RMAges 18–75 - NCT05690737Recruiting
Tai chi program to prevent episodic migraine
This trial tests whether a tai chi routine can help prevent episodic migraine attacks and reduce bothersome symptoms like nausea or light/sound sensitivity. It also looks at how tai chi may change the brain or body processes involved in migraine.
Hong Kong, HONG KONGAges 18–65 - NCT05741775RecruitingPhase 3
Physiotherapy program for migraine symptoms
This trial tests whether a physiotherapy treatment can reduce migraine symptoms. You may be eligible if you have likely migraine headaches and meet the trial’s symptom screening rules.
Kajang, SelangorAges 18–40 - NCT06112093RecruitingPhase 1
Magnetic brain stimulation for headaches after a concussion
This study tests whether a non-invasive magnetic pulse treatment (repetitive transcranial magnetic stimulation) can help people with long-lasting headaches following a mild concussion. If you are 18 to 55 years old and have had daily headaches for at least 3 months after your head injury, this study may help find a new way to relieve your pain.
Syracuse, New YorkAges 18–55 - NCT06134791Recruiting
Comparing neck test results in cervicogenic headache patients
This study compares people with cervicogenic headache (headache from neck problems) to see if a simple neck test can tell them apart. It aims to help doctors diagnose this type of headache better.
Ghent, Oost-VlaanderenAges 18 years+ - NCT06219694Recruiting
Laser acupuncture for chronic migraine
This trial tests whether laser acupuncture can help people whose chronic migraine medications aren't working well. It's a non-invasive treatment that uses low-level laser light on specific points on the body.
Taichung, Xitun DistrictAges 20 years+ - NCT06248671RecruitingPhase 2
Atorvastatin for preventing migraine attacks
This trial tests whether a daily dose of atorvastatin (a common cholesterol medicine) can prevent migraine attacks in people with episodic migraine. You would keep a headache diary and be randomly assigned to take atorvastatin or a placebo for about 3 months.
BergenAges 18–65 - NCT06401642RecruitingPhase 4
Zavegepant for acute migraine with CGRP preventives
This study tests how well a new acute migraine medicine, zavegepant, works and is tolerated in people who are already taking a CGRP-targeting preventive medication. It may help you find an effective treatment when you get a migraine attack.
Phoenix, ArizonaAges 18 years+ - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT06485336RecruitingPhase 2
Atorvastatin for prevention of chronic migraine
This trial tests whether the cholesterol drug atorvastatin can reduce the number of migraine days in people with chronic migraine (15 or more headache days per month, including at least 8 migraine days). If you have frequent migraines and haven't tried statins before, this study may offer a new preventive option.
BergenAges 18–65 - NCT06485726RecruitingPhase 4
Comparing valproate and propranolol for migraine prevention
This study compares two common migraine prevention medications—valproate (a seizure medicine) and propranolol (a blood pressure medicine)—to see which works better for people with migraines who have never tried prevention before. You may benefit if you experience migraines and are looking for a safe first-line preventive option.
Kafr ash ShaykhAges 18–75 - NCT07694063Recruiting
Online yoga for frequent migraines
This trial tests if online Hatha yoga classes can help adults who have frequent migraines (but not daily). If you have migraines 8–14 days a month and are already on stable medication, this study may offer a gentle addition to your treatment.
Seville, SevillaAges 18–65 - NCT05156398RecruitingPhase 3
Rimegepant to prevent migraine attacks in children
This trial studies whether rimegepant can reduce how often migraine attacks happen in children and teens. It also looks at safety and how well the treatment fits day-to-day life and school activities.
Fort Smith, ArkansasAges 6–17 - NCT06503848Recruiting
Migraine attack treatment response biomarkers study
This study looks at how your body responds to migraine attack treatment, by tracking symptoms and blood markers. It may help find better ways to treat migraines in the future.
BarcelonaAges 18–45 - NCT06504537Recruiting
Theragun vs compression therapy for migraine relief
This study compares two handheld massage devices—a percussive therapy device (Theragun) and a compression therapy device—to see which works better for migraine pain. If you have frequent migraines without aura, this could help you find a simple, drug-free treatment option.
Lahore, Punjab ProvinceAges 18–65 - NCT06509503RecruitingPhase 4
Effect of birth control pills on migraine
This study tests how combined oral contraceptive pills affect migraine in women. It will compare people who take these pills with those using non-hormonal methods like an IUD, to see if the pills help or change the migraine pattern.
Kafr ash ShaykhAges 18–55 - NCT06537700Recruiting
Testing Botox for Chronic Migraine: Does Timing Matter?
This study tests how well Botox works for chronic migraine patients, depending on how long they've had the condition. If you have chronic migraines, haven't had Botox recently, and meet a few other conditions, you may be able to join.
AnconaAges 18–70 - NCT06602479RecruitingPhase 2
Study of MEDI0618 for episodic migraine
This trial tests a new medicine, MEDI0618, against a placebo for people with episodic migraine. The goal is to see if MEDI0618 is safe and effective at reducing migraine days.
Birmingham, AlabamaAges 18–70 - NCT06623188Recruiting
Ear stimulation for treating episodic migraine
This trial tests if a device that gently stimulates the ear can reduce migraine attacks. It is for adults with regular migraines who have not had success with at least two preventive medications.
MarseilleAges 18–60 - NCT06628921Recruiting
Eptinezumab for treating a migraine attack right now
This trial tests if eptinezumab can stop a migraine attack that is already happening. It may help people who get migraines often and are already part of the TACHIS study.
RomaAges 18 years+ - NCT06735768Recruiting
Daily magnetic brain stimulation to prevent migraines
This study tests a type of magnetic brain stimulation (repetitive TMS) given daily at home to prevent migraines. It may be an option if your migraine medications aren't enough or you want a non-drug treatment.
Vienna, State of ViennaAges 18–65 - NCT06735833Recruiting
Testing embolization for chronic migraines
This study tests a procedure called MMA embolization (blocking a small artery in the head) to see if it can reduce migraine attacks in people with chronic, hard-to-treat migraines.
Phoenix, ArizonaAges 18–65
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Common questions
- Are there clinical trials for migraine headache, with or without aura?
- Yes. Clin2 currently lists 193 recruiting migraine headache, with or without aura studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine headache, with or without aura trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine headache, with or without aura trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.