Clinical trials
Multiple System Atrophy clinical trials
Below are recruiting multiple system atrophy clinical trials, each written for real people, not researchers. We’re tracking 62 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07863180RecruitingPhase 1/Phase 2
Tributyrin for progressive supranuclear palsy
This trial tests a supplement called tributyrin to see if it can help people with progressive supranuclear palsy (PSP), a condition that affects movement and balance. The study is done virtually, so you can participate from home with a caregiver's help.
Ann Arbor, MichiganAges 45 years+ - NCT07805967Recruiting
Study of rare parkinsonian conditions
This study follows people with certain rare brain conditions that affect movement and thinking, such as multiple system atrophy, dementia with Lewy bodies, progressive supranuclear palsy, and corticobasal degeneration. It aims to learn more about how these conditions progress over time, which may help improve future care.
Changshu, JiangsuAges 18 years+ - NCT07729852Enrolling by invitationPhase 2
Continuing access to ATH434 after the earlier study
This trial lets people who finished the earlier ATH434-201 study keep getting ATH434 (an experimental drug) on an open-label basis, meaning everyone knows they get the drug. If you were in that study and want to continue, this may help you keep receiving the treatment.
Toulouse, Midi-PyreneesAges Any age - NCT06645626Recruiting
Health service use and quality of life in atypical Parkinson's
This study looks at how people with certain rare brain conditions (like progressive supranuclear palsy, corticobasal syndrome, or multiple system atrophy) use healthcare services and how their quality of life is affected. It may help doctors better support patients and their carers.
Southampton, HampshireAges 18 years+ - NCT07640542RecruitingEarly Phase 1
Brain imaging study for Parkinson's and MSA patients
This early-stage research trial tests a new brain-imaging tracer called [11C]MODAG-005 to help doctors better understand Parkinson's disease (PD) and multiple system atrophy (MSA). You would undergo PET/CT and MRI scans twice, a few weeks apart, to see how reliable the imaging is.
Tübingen, Baden-WurttembergAges 50–75 - NCT07640555RecruitingEarly Phase 1
Brain imaging study for Parkinson's and related movement disorders
This research study tests a new type of brain scan (called a PET scan) that may help detect early signs of Parkinson's disease and similar conditions. You'll receive the scan and may have a spinal tap to check for specific protein markers.
New Haven, ConnecticutAges 50–80 - NCT06174948Recruiting
CUE1 device for Parkinson's and related movement disorders
This trial tests a small device called CUE1 that gives gentle vibrations on the chest to help improve movement and balance in people with Parkinson's disease and similar conditions. It may help if you have trouble with walking or stability.
LondonAges 18 years+ - NCT07604116RecruitingPhase 1
Testing a new imaging agent for Parkinson's and related conditions
This study tests an investigational imaging agent called SST001, which may help doctors see a protein linked to Parkinson's disease (PD) and multiple system atrophy (MSA) in the body. It will be given to healthy volunteers and patients with PD or MSA to check safety, how it spreads, and how the body handles it.
Wuxi, JiangsuAges 18 years+ - NCT07570212Recruiting
Personalized Brain Stimulation for Parkinson's and Similar Disorders
This study tests whether customized transcranial magnetic stimulation (a non-invasive technique that uses magnetic pulses to stimulate brain activity) can help improve symptoms in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The treatment is tailored to each person's brain activity patterns.
Beijing, Beijing MunicipalityAges 30–80 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT06162013RecruitingPhase 2
NAD supplement trial for atypical parkinsonism
This trial tests whether a supplement called nicotinamide riboside (NR) can help people with rare forms of parkinsonism (PSP, MSA, or CBS). It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real supplement or a placebo.
Oslo, OsloAges 30–85 - NCT06120049RecruitingPhase 2/Phase 3
Comparing new PET scans for Parkinson's, MSA, Lewy body dementia, and Alzheimer's
This study tests if a new radioactive tracer called [18F]-MFBG can help doctors better distinguish between Parkinson's disease, multiple system atrophy (MSA), dementia with Lewy bodies, and Alzheimer's disease. It compares the new scan with two standard scans to see which is most accurate.
Ghent, GentAges 18–85 - NCT07392411Recruiting
AI study of face and speech in Parkinson's disease
This study uses artificial intelligence to analyze facial expressions and speech patterns in people with Parkinson's disease, multiple system atrophy, or progressive supranuclear palsy. The goal is to find digital markers that may help track the disease.
Beijing, Beijing MunicipalityAges 15–75 - NCT06838637Recruiting
Spinal cord stimulation at home for blood pressure issues
This trial tests using a gentle electrical device on your spine at home to help with dizziness from low blood pressure (orthostatic hypotension). It is for people with chronic spinal cord injury or multiple system atrophy who live in British Columbia.
Vancouver, British ColumbiaAges 19–70 - NCT07353463Recruiting
Parkinson's and MSA study with biosamples and imaging
This study collects data from people with Parkinson's disease or multiple system atrophy (MSA) to better understand these conditions. You will have blood, saliva, optional spinal fluid tests, and brain scans (MRI, PET/SPECT).
ShanghaiAges Any age - NCT04706234Recruiting
Check swallowing and voice function in neurodegenerative diseases
This study looks at how well the throat and voice-related functions work in people with certain long-term brain or nerve conditions. It uses a specific throat exam during FEES to better understand swallowing and laryngopharyngeal (throat-area) function.
Innsbruck, TyrolAges 18 years+ - NCT06949865Recruiting
AI-enhanced levodopa challenge test for parkinsonism
This study uses artificial intelligence (AI) to improve a standard test for parkinsonism called the levodopa challenge test. It may help doctors better understand how your movement symptoms respond to levodopa, a common Parkinson's medication.
BeijingAges 50–75 - NCT07081841Enrolling by invitation
Long-term follow-up for AB-1005 study participants
This trial is for people with Parkinson's disease or multiple system atrophy (parkinsonian type) who took part in an earlier AB-1005 study. It will continue to monitor your health over time to learn more about the treatment's long-term effects.
San Francisco, CaliforniaAges Any age - NCT06891703RecruitingEarly Phase 1
PET imaging study for Parkinson's and related conditions
This trial uses a new imaging agent (like a dye) to see signs of Parkinson's disease in the brain. If you have Parkinson's or a related condition like Lewy body dementia or multiple system atrophy, this scan may help researchers better understand these illnesses.
SolnaAges 20 years+ - NCT06683365RecruitingPhase 1
Nerve graft trial for Parkinson's or MSA
This trial tests whether grafting a piece of your own leg nerve into a specific part of the brain can improve symptoms of Parkinson's disease or multiple system atrophy (MSA). It aims to help people whose movement problems are moderate but not too severe.
Lexington, KentuckyAges 40–75 - NCT06596746Recruiting
Tracking markers for neurodegenerative diseases
This study tracks changes in people with Parkinson's disease, other movement disorders, or cognitive decline to find better ways to measure disease progression.
Cassino, FrosinoneAges 10 years+ - NCT02897063RecruitingPhase 1
Test medicines for low blood pressure in nerve-related disorders
This early (Phase 1) study tests whether midodrine and droxidopa can improve blood-flow pooling in the belly in people with nerve problems that affect blood pressure when standing. It’s looking at safety and how the body responds, which may help reduce dizziness or fainting for some participants.
Nashville, TennesseeAges 40–80 - NCT06098612RecruitingEarly Phase 1
PET imaging study for Parkinson's and related disorders
This study uses a new PET scan tracer called [11C]SY08 to take pictures of the brain in people with Parkinson's, multiple system atrophy, or dementia with Lewy bodies. It aims to see if this tracer can help better understand and tell apart these conditions.
Charlestown, MassachusettsAges 50–80 - NCT05826457Enrolling by invitation
Study for early RBD as a possible Parkinson’s risk
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for multiple system atrophy?
- Yes. Clin2 currently lists 62 recruiting multiple system atrophy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple system atrophy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple system atrophy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.