Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,065 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06666283RecruitingPhase 1
Testing a new drug for diabetic kidney disease
This study tests a new medicine called AP303 for people with type 2 diabetes and chronic kidney disease. The goal is to see if it is safe and how the body processes it. If you have diabetes and your kidneys are not working as well as they used to, this trial might help find new treatment options.
Beijing, Beijing MunicipalityAges 30 years+ - NCT06668454Recruiting
Chemoimmunotherapy before surgery for limited spread esophageal cancer
This trial tests a treatment plan that combines chemotherapy with immunotherapy, followed by surgery, for people whose esophageal or stomach cancer has spread to a few areas (oligometastatic). The goal is to see if this approach can shrink the cancer and improve outcomes.
Toronto, OntarioAges 18–80 - NCT06669702Recruiting
Exercise therapy for axial spondyloarthritis on biologics
This study tests whether a supervised exercise program can help people with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine) who are already on biologic medications. It aims to see if exercise reduces inflammation and improves symptoms.
Loughborough, LeicestershireAges 18 years+ - NCT06669715Recruiting
Physical fitness and heart health in adults
This study looks at physical fitness and blood flow in a wide range of adults. It aims to understand how fitness affects heart health across different people.
LjubljanaAges 18 years+ - NCT06671054RecruitingPhase 2
Testing AP1189 for newly diagnosed active rheumatoid arthritis
This study tests an oral drug called AP1189 for people just diagnosed with active rheumatoid arthritis who haven't yet taken standard arthritis medicines. You may be able to take part if your disease is very active and you're ready to try a new treatment option.
Cutler Bay, FloridaAges 18 years+ - NCT06671119Recruiting
Weight regain treatment after sleeve gastrectomy with mucosal ablation
This trial tests a procedure to help people who have regained weight after a sleeve gastrectomy. It uses a special technique to treat the stomach lining and may help you lose weight again.
Cary, North CarolinaAges 22–60 - NCT06671236RecruitingPhase 1
Treg cell therapy for ALS
This trial tests a new type of cell therapy called regulatory T cells (Tregs) for people with neurodegenerative diseases like ALS. The goal is to see if these cells can slow down the disease.
Zhengzhou, HenanAges 18–70 - NCT06671535Recruiting
Dialysis filter for itching in hemodialysis patients
This study tests a special type of dialysis filter (made of PMMA) to see if it can reduce severe itching and improve quality of life for people on long-term dialysis. If you have bothersome itching that standard treatment hasn't helped, this trial might be an option for you.
Saint PetersburgAges 18 years+ - NCT06673498RecruitingPhase 2
Two drugs to raise platelets before surgery in liver disease
This trial tests two medications (lusutrombopag and recombinant human thrombopoietin) given together to raise platelet levels before a planned surgery in people with chronic liver disease. The goal is to reduce the need for platelet transfusions and make the procedure safer.
Fuyang, AnhuiAges 18 years+ - NCT06676046Recruiting
Study of rare cholesterol and fat disorders
This study looks at people with rare or unusual cholesterol, fat, or heart-related conditions. It helps researchers learn more about these disorders and improve testing. You do not need to have a known diagnosis to join initially.
Bethesda, MarylandAges 10–90 - NCT06678191Recruiting
Triple combo inhaler study for uncontrolled asthma
This study tests a fixed triple combination inhaler (Trimbow) for people whose asthma is not well controlled with their current treatment. It looks at how well this inhaler works in everyday life over time.
BékéscsabaAges 18 years+ - NCT06680128RecruitingPhase 1/Phase 2
Testing mRNA Japanese encephalitis vaccines in healthy adults
This trial tests two new mRNA vaccines for Japanese encephalitis, a brain infection spread by mosquitoes. It aims to find the safest and most effective dose in healthy adults, with a first stage in younger adults and a second stage in all adults.
BrisbaneAges 18 years+ - NCT06683846RecruitingPhase 2
Ivonescimab for advanced rare tumors: a safety & early-efficacy study
This trial tests a drug called ivonescimab in people with advanced, rare tumor types that have spread (stage IV). The goal is to see if the drug is safe and whether it can shrink tumors or slow their growth.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06685042RecruitingPhase 1/Phase 2
CAR T-cell therapy for severe autoimmune diseases
This study tests a new treatment called CAR T-cell therapy for people with severe autoimmune diseases that haven't gotten better with standard treatments. The goal is to see if it can help control the disease by reprogramming your immune cells.
Rome, LazioAges 18–65 - NCT06685094Recruiting
Pain, movement, and quality of life study for Albanian speakers
This study is translating health questionnaires into Albanian to better understand pain, movement, mood, and quality of life. It aims to help people with muscle, joint, or back pain.
Murcia, MurciaAges 18–80 - NCT06685107Recruiting
Virtual reality for pain relief in older ER patients
This trial tests if using virtual reality along with standard pain medication helps reduce pain better than medication alone for older adults with muscle or joint pain in the emergency room.
Brooklyn, New YorkAges 65–120 - NCT06687122Recruiting
Eggs, metabolism, and choline study
This trial studies how eating 3 eggs daily for 4 weeks affects your metabolism and choline levels. It may help if you have obesity and are looking for a simple dietary change to improve your health.
Québec, QuebecAges 30–65 - NCT06687590Recruiting
Serranator POINT FORCE registry for leg and dialysis access
This registry study is following patients whose blocked leg or dialysis access arteries are treated with a special balloon (Serranator) that helps open the vessel. The goal is to see how well the device works in real-world use.
Scottsdale, ArizonaAges 18 years+ - NCT06688396Recruiting
Finding early signs of dilated cardiomyopathy with AI and mobile screening
This trial uses a smartphone app to screen first-degree relatives of people with dilated cardiomyopathy (DCM) for early signs of the condition. It aims to detect heart muscle weakness before symptoms start, so that treatment can begin sooner.
Lancaster, PennsylvaniaAges 18 years+ - NCT06688461Recruiting
Exercise study to improve blood sugar in type 2 diabetes
This study tests whether high-intensity interval training can improve how your body uses insulin. It is for people with type 2 diabetes who are not on insulin and have had diabetes for 1 to 5 years.
SantiagoAges 45–75 - NCT06690658Recruiting
Home arm exercises with a robotic trainer
This trial tests whether a robotic trainer can help people do upper body exercises on their own. It may be a good fit if you can sit without back support and follow simple instructions.
Raanana, IsraelAges 18 years+ - NCT06690931Recruiting
Brain training with electrical stimulation and virtual reality for Parkinson's
This study tests a new type of therapy that combines brain training (neurofeedback), mild electrical stimulation to help with movement, and virtual reality exercises. It aims to improve walking and movement for people with Parkinson's disease.
Schiedlberg, Upper AustriaAges 40–80 - NCT06691867Recruiting
Integrative training for sickle cell pain in teens
This study tests an integrative training program designed to help adolescents with sickle cell disease manage their pain better. It combines physical and mental techniques to reduce pain and improve quality of life.
Hartford, ConnecticutAges 12–18 - NCT06693271Recruiting
Protein, blueberries, and exercise for heart health in older adults
This trial tests whether adding protein powder, blueberries, and a gentle exercise program together can improve heart health and reduce frailty in people 65 and older.
Halifax, Nova ScotiaAges 65 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,065 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.