Clinical trials
Neurocognition clinical trials
Below are recruiting neurocognition clinical trials, each written for real people, not researchers. We’re tracking 172 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT05576103Recruiting
Study of brain tumor thinking and MRI during radiation
This study follows adults with a primary brain tumor to understand how thinking skills and brain images change over time during radiation therapy. It may help researchers measure treatment effects and better track brain changes.
San Diego, CaliforniaAges 18–99 - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT05597410Recruiting
Study of people at risk for Alzheimer’s in Shanghai
This study follows people who are closely related to someone diagnosed with Alzheimer’s to see who develops memory or brain changes over time. It may help researchers understand risk and early signs, which could guide prevention in families like yours.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT05658731Recruiting
Radiation planning study to protect thinking in children
This study compares how radiation is planned to see whether it better protects thinking and memory in children and young adults. It may help future patients by learning which planning approach leads to better cognitive (thinking) outcomes.
Washington D.C., District of ColumbiaAges 1–26 - NCT05668598Recruiting
Memory check study for older adults with and without dementia
This study creates a practical tool to measure “episodic memory,” which is your ability to recall events from daily life. It includes adults age 70+ with different memory levels, to see how well the tool works for people with dementia and for those without.
LensAges 70 years+ - NCT05702645Recruiting
Down syndrome long-term study after leukemia treatment
This study follows children and young adults with Down syndrome who have survived acute leukemia (ALL or AML) to learn about their longer-term health after treatment ends. It may help families and doctors understand what health problems to watch for and how to provide better follow-up care.
Birmingham, AlabamaAges 6–39 - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT05754567Recruiting
Study brain and development outcomes in CONCEPTT kids
This study looks at children’s neurodevelopment (how the brain, learning, and development are going) whose mothers took part in the earlier CONCEPTT trial. It may help researchers understand how having type 1 diabetes in pregnancy can relate to a child’s development.
Calgary, AlbertaAges 6 years+ - NCT05765162Recruiting
Research study on safer, more tailored anesthesia
This study looks at safer anesthesia—meaning medicines used during procedures—using a more personalized approach. It may help make anesthesia safer for adults having medical procedures.
Nykøbing FalsterAges 18–100 - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD and thinking problems in Veterans
This study tests whether methylphenidate (a stimulant medicine) can improve PTSD symptoms and help with memory or thinking problems people report. It may help Veterans who have both PTSD and recent cognitive difficulties.
Birmingham, AlabamaAges 18–65 - NCT05802680Recruiting
Near-infrared light study for brain effects in adults
This study tests how non-invasive near-infrared light may affect brain function. You may be able to join if you’re an adult, since there are no other listed eligibility restrictions.
Austin, TexasAges 18 years+ - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT05929703Recruiting
Care approach for hospitalized older adults at risk of confusion
This trial tests new ways to help hospitalized older adults (and their family/care partners) stay comfortable and avoid or reduce episodes of acute confusion. It focuses on people who are likely to develop delirium during their hospital stay.
Orange, CaliforniaAges 70 years+ - NCT05943834Recruiting
Voice testing to detect early memory and mood changes
This trial studies whether automated analysis of your voice and speech can help detect early signs of Alzheimer’s disease and mood (affective) problems. It may help identify changes sooner, using voice and questionnaire information from people who are cognitively healthy to very mildly affected.
NiceAges 50–100 - NCT06036095RecruitingPhase 4
Comparing two types of anesthesia in older adults having surgery
This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.
Portland, OregonAges 70–110 - NCT06036706Recruiting
Radiation types and thinking skills for skull base meningioma
This study compares different radiation methods for treating a slow-growing, non-cancerous brain tumor at the base of the skull. It aims to see which approach best protects memory and thinking abilities.
CaenAges 20–65 - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT06098235Recruiting
Test of the Oriental diet for brain health in people at high stroke risk
This trial tests whether a special diet (the Oriental diet) can help protect thinking and memory in people who have several stroke risk factors. It may be a good fit if you are 40 or older and have three or more stroke risk factors, such as high blood pressure, diabetes, or being overweight.
Hangzhou, ZhejiangAges 40 years+ - NCT06143488Recruiting
Clot removal vs. best medicine for mild stroke with large vessel blockage
This trial tests whether removing a blood clot from a large brain artery is better than standard medical care for people who have a mild stroke (NIHSS score 2-5) but still have symptoms like trouble speaking, weakness, or confusion. It is for patients who can be treated within 24 hours of their last known well time.
Wuhu, AnhuiAges 18 years+ - NCT06150352Recruiting
Sleep apnea and memory in older adults with mild concerns
This trial looks at how sleep apnea affects memory and brain health in people who have mild memory problems or are worried about their memory. You will have a sleep study and brain scans to see if treating sleep apnea could help protect your thinking skills.
Hong KongAges 50–80 - NCT06186089Recruiting
How stomach surgery affects gut bacteria and your thinking
This study looks at how having stomach cancer surgery changes your gut bacteria and thinking abilities. Researchers want to understand if these changes affect memory or brain function after the operation.
Wuhan, HubeiAges 40–80
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Common questions
- Are there clinical trials for neurocognition?
- Yes. Clin2 currently lists 172 recruiting neurocognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurocognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurocognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.