Clinical trials
Neurocognition clinical trials
Below are recruiting neurocognition clinical trials, each written for real people, not researchers. We’re tracking 164 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06475521Enrolling by invitation
Study of a new infant formula for healthy babies
This study tests a new infant formula to see how healthy babies grow and develop. If your baby is healthy, full-term, and formula-fed, they may be able to join.
DupnitsaAges birth–2 weeks - NCT06452147Recruiting
Anesthesia types for preventing confusion after hip surgery in older adults
This study looks at different ways to give anesthesia during hip surgery to help older patients think and remember better afterward. It may help prevent confusion or memory problems that sometimes happen after surgery.
Dongyang, ZhejiangAges 65 years+ - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06400121RecruitingPhase 2
Apimostinel plus brain training for depression
This study tests if a new drug called apimostinel, combined with computer-based brain training exercises, can improve depression symptoms. It may help people with major depression who also have negative thoughts about themselves.
Pittsburgh, PennsylvaniaAges 18–60 - NCT06237218Recruiting
Occupational therapy to prevent falls in older adults with dementia
This program tests whether a special type of home-based occupational therapy (called COTID) can help older adults with dementia avoid falling again after a fall that sent them to the hospital. It compares this new approach to usual occupational therapy care.
LimogesAges 75 years+ - NCT06227962Enrolling by invitation
Thinking and quality of life in retinoblastoma survivors
This study looks at how retinoblastoma and its treatment affect thinking skills and quality of life over time. It may help doctors better support survivors and their families.
Amsterdam, North HollandAges 6 months–35 years - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT06143488Recruiting
Clot removal versus medication for mild stroke with large vessel blockage
This trial compares a procedure to remove the blockage (endovascular therapy) with the best medications alone for people who have a mild stroke caused by a large blocked artery in the brain. The goal is to see if the procedure can improve recovery better than medicine alone.
Wuhu, AnhuiAges 18 years+ - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT04107285Recruiting
Study brain changes in people with lymphoma after CAR T
This study looks at how thinking and brain function change over time in people with lymphoma who receive CAR T therapy. It may help doctors understand side effects and better support patients during and after treatment.
New York, New YorkAges 18 years+ - NCT05367245RecruitingPhase 2
Butyrate supplement for Gulf War illness symptoms
This Phase 2 study tests whether a calcium–magnesium butyrate supplement can reduce symptoms of Gulf War Illness (GWI), especially by targeting gut and immune-related pathways. You may be eligible if you’re a Gulf War–era veteran with moderate-to-severe physical symptoms and no conditions or medicines that could explain them instead.
Long Beach, CaliforniaAges 40–70 - NCT05943834Recruiting
Voice testing to detect early memory and mood changes
This trial studies whether automated analysis of your voice and speech can help detect early signs of Alzheimer’s disease and mood (affective) problems. It may help identify changes sooner, using voice and questionnaire information from people who are cognitively healthy to very mildly affected.
NiceAges 50–100 - NCT02914067Recruiting
Testing brain scan and computer measures in young brain tumor patients
This study looks at “brain biomarkers,” meaning brain signals measured on MRI and thinking/learning tests on a computer. It may help researchers understand how brain tumors affect the brain and track changes over time.
St Louis, MissouriAges 4–18 - NCT05929703Recruiting
Caring for hospitalized older adults
This study tests a new approach to caring for older adults in the hospital to prevent confusion (delirium). It involves having a family member or care partner stay with the patient during the hospital stay.
Orange, CaliforniaAges 70 years+ - NCT05913544Recruiting
Integrative therapy for young adults with borderline personality disorder
This trial tests a short integrative therapy program along with repeated thinking (neurocognitive) and mental health assessments for young adults with borderline personality disorder (BPD). It may help improve symptoms and cognitive functioning by combining structured therapy and targeted evaluations.
NîmesAges 16–25 - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05802680Recruiting
Near-infrared light study for brain effects in adults
This study tests how non-invasive near-infrared light may affect brain function. You may be able to join if you’re an adult, since there are no other listed eligibility restrictions.
Austin, TexasAges 18 years+ - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT05754567Recruiting
Study brain and development outcomes in CONCEPTT kids
This study looks at children’s neurodevelopment (how the brain, learning, and development are going) whose mothers took part in the earlier CONCEPTT trial. It may help researchers understand how having type 1 diabetes in pregnancy can relate to a child’s development.
Calgary, AlbertaAges 6 years+ - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT05702645Recruiting
Down syndrome long-term study after leukemia treatment
This study follows children and young adults with Down syndrome who have survived acute leukemia (ALL or AML) to learn about their longer-term health after treatment ends. It may help families and doctors understand what health problems to watch for and how to provide better follow-up care.
Birmingham, AlabamaAges 6–39 - NCT05668598Recruiting
Memory check study for older adults with and without dementia
This study creates a practical tool to measure “episodic memory,” which is your ability to recall events from daily life. It includes adults age 70+ with different memory levels, to see how well the tool works for people with dementia and for those without.
LensAges 70 years+ - NCT05658731Recruiting
Radiation planning study to protect thinking in children
This study compares how radiation is planned to see whether it better protects thinking and memory in children and young adults. It may help future patients by learning which planning approach leads to better cognitive (thinking) outcomes.
Washington D.C., District of ColumbiaAges 1–26
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Common questions
- Are there clinical trials for neurocognition?
- Yes. Clin2 currently lists 164 recruiting neurocognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neurocognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neurocognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.