Clinical trials
Neuroinflammation clinical trials
Below are recruiting neuroinflammation clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07772141Recruiting
Palmitoylethanolamide for chronic low back pain
This trial tests whether a natural substance called palmitoylethanolamide (PEA) can help reduce chronic low back pain by calming the nervous system and reducing inflammation. It might be an option for people with ongoing pain from a disc problem who haven't had surgery.
Banī SuwayfAges 18–65 - NCT06453915RecruitingEarly Phase 1
Brain PET scan for inflammation in fatty liver disease
This study uses a special PET scan to look for inflammation in the brain related to fatty liver disease. It may help researchers understand how liver health affects brain function.
Sacramento, CaliforniaAges 18 years+ - NCT07222306Enrolling by invitation
Cannabis, brain inflammation, and suicidal thoughts brain imaging study
This study uses brain scans to see how cannabis affects inflammation and suicidal thoughts. You may join if you're already in a related study and can safely undergo MRI and PET scans.
Detroit, MichiganAges 19–69 - NCT05656105RecruitingEarly Phase 1
PET scan study of brain inflammation after COVID
This early-phase study uses a special PET scan to look for signs of brain inflammation in people with ongoing (long-term) nervous system symptoms after COVID-19. It may help researchers understand what is driving symptoms and whether this imaging approach can detect inflammation.
Birmingham, AlabamaAges 18–65 - NCT06746909Recruiting
Brain inflammation and imaging in older adults at risk for dementia
This study looks at how changes in the brain (like inflammation) relate to thinking and memory decline in older adults. It uses brain scans and computer tools to find early signs of dementia risk, with the goal of better preventing memory loss.
PisaAges 65–89 - NCT07200726Recruiting
Brain inflammation and thinking after heart surgery
This study looks at whether brain inflammation during heart surgery may affect memory and thinking. It includes people aged 60 and older who are having planned heart surgery.
Genk, LimburgAges 60 years+ - NCT03457493RecruitingPhase 1/Phase 2
TSPO brain scan study in Parkinson’s disease
This trial looks at brain inflammation in people with Parkinson’s using a special PET scan. The goal is to understand how brain immune activity may relate to Parkinson’s, and how the scan results change over time.
Birmingham, AlabamaAges 30 years+ - NCT03759522RecruitingPhase 1
PET brain scan for inflammation in MS, fibromyalgia, or CFS
This early-stage study tests an imaging medicine ([F-18]DPA-714) that can help researchers see inflammation in the brain and nervous system. It may help doctors better understand how “inflammation signals” differ across conditions like multiple sclerosis, fibromyalgia, and chronic fatigue syndrome.
Birmingham, AlabamaAges 18–65 - NCT04106830Recruiting
Study to follow neuroinflammation and demyelination diseases with imaging
This study builds a China-based group of people with neuroinflammatory and demyelination diseases and collects health and MRI (brain scan) information. It may help doctors better understand these conditions over time and improve future treatments.
Beijing, Beijing MunicipalityAges 16–75 - NCT04810858Recruiting
Study how chronic marijuana affects brain inflammation in HIV
This study looks at whether ongoing marijuana use changes “brain inflammation” and brain cell injury in people living with HIV. It may help researchers understand potential risks or protective effects and how treatment and brain health interact.
Winston-Salem, North CarolinaAges 25–59 - NCT05066308RecruitingPhase 2
Cannabidiol to reduce inflammation in chronic low back pain
This Phase 2 study tests cannabidiol (CBD) to calm inflammation in the brain that may be linked to chronic low back pain. If you qualify, you’ll take study CBD and undergo brain imaging to see whether inflammation changes.
Boston, MassachusettsAges 18–75 - NCT05233605Recruiting
Study sedative effects on ongoing brain inflammation after severe COVID
This study looks at whether a specific ICU sedative (dexmedetomidine) affects long-term inflammation in the brain after severe COVID with ARDS and deep sedation. It uses PET and MRI scans and special tracers to understand persistent inflammation and why it may last.
ParisAges 18–74 - NCT05514899RecruitingPhase 2
Cannabidiol and THC study for gut health and brain inflammation in HIV
This Phase 2 study tests whether cannabidiol (CBD) and tetrahydrocannabinol (THC) change the gut microbiome and brain-related inflammation in people with HIV. It may help researchers understand new ways to reduce inflammation, but you would need strict cannabis and CBD/THC avoidance during the study.
San Diego, CaliforniaAges 21–70 - NCT06005363Recruiting
Brain fluid study in shunt surgery patients
This study looks at brain fluid and drainage function in patients receiving a VP shunt for hydrocephalus. It may help understand how the brain clears waste products.
TaoyuanAges 60 years+ - NCT06146062RecruitingPhase 2
Stem cell therapy for severe traumatic brain injury
This trial tests whether a single infusion of stem cells from donated umbilical cord tissue can help calm inflammation in the brain after severe traumatic brain injury. It is for patients aged 18–50 who need brain pressure monitoring and are not responding to verbal commands 5 days after sedation is stopped.
ClamartAges 18–50 - NCT06280742Recruiting
Brain inflammation in multiple sclerosis: a PET-MRI imaging study
This study uses a special PET-MRI scan to look at brain inflammation in people with relapsing-remitting multiple sclerosis (RRMS). It may help researchers understand how inflammation changes when starting a stronger MS treatment.
LyonAges 18 years+ - NCT06467773Recruiting
PET/MRI scan to track brain inflammation in stroke and MS
This study uses a special kind of PET/MRI scan to look at inflammation in the brain and spinal cord. It may help people with conditions like stroke, multiple sclerosis, or other immune-related brain diseases.
Wuhan, HubeiAges 18 years+ - NCT06551649Recruiting
Test of cell-based treatment for ALS and MS
This study tests a therapy made from human amniotic cells to help reduce brain inflammation and damage. It may be an option for people with ALS or multiple sclerosis who meet the age and health requirements, as well as healthy volunteers to serve as a comparison group.
RomaAges 20–60 - NCT06574165Recruiting
Pain, mood, and brain inflammation in veterans with fibromyalgia
This study looks at how brain inflammation and mood relate to pain in veterans with fibromyalgia. It may help find new ways to treat pain by understanding these connections.
Birmingham, AlabamaAges 19–85 - NCT06725719Recruiting
TSPO PET scan study for people with tumors
This study tests a special PET scan that looks at a protein called TSPO, which may be active in tumors. It may help doctors understand and monitor certain cancers better.
Hefei, AnhuiAges 18–80 - NCT06745583RecruitingPhase 2
Testing an oral drug for brain inflammation in Alzheimer's
This study tests an experimental oral medication (EI-1071) to see if it can reduce brain inflammation in people with Alzheimer's disease. The goal is to learn if it is safe and might help slow cognitive decline.
TaipeiAges 50–85 - NCT06945614RecruitingPhase 1
Xenon gas for brain inflammation safety study
This study tests an inhaled gas called xenon to see if it can safely reduce brain inflammation. The study is for healthy volunteers aged 55-75 to check safety and early signs of benefit.
Boston, MassachusettsAges 55–75 - NCT06973837Recruiting
Brain study on chronic back pain and insomnia
This study looks at how the brain works in people with chronic low back pain and/or chronic insomnia. It compares these groups to healthy volunteers using MRI and pain tests.
LeuvenAges 18–60 - NCT06977204Recruiting
Exercise and brain health in Parkinson's disease
This study looks at whether physical activity can reduce inflammation in the brain for people with Parkinson's disease. It aims to understand how exercise might help slow the progression of the disease.
Pavia, PaviaAges 40–80
Hear when a new Neuroinflammation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for neuroinflammation?
- Yes. Clin2 currently lists 32 recruiting neuroinflammation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuroinflammation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuroinflammation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.