Clinical trials
Neuromodulation clinical trials
Below are recruiting neuromodulation clinical trials, each written for real people, not researchers. We’re tracking 202 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05798143Recruiting
Testing brain-signal biomarkers in treatment-resistant depression
This trial studies signs in the brain (biomarkers) during an accelerated form of nerve stimulation to treat depression that hasn’t improved with usual antidepressants. It may help researchers learn who benefits and how to better personalize treatment.
ChietiAges 18–65 - NCT05820074Recruiting
Neural signals and walking changes in Parkinson’s patients
This study measures brain and nerve “biomarkers” to understand how Parkinson’s affects walking and balance. It may help researchers identify signs that relate to gait problems, and participants with a specific implanted stimulator may be able to take part in testing with stimulation turned off.
Vitznau, Canton of LucerneAges 18 years+ - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT05839535RecruitingPhase 2
Baduanjin plus brain stimulation for knee osteoarthritis pain
This Phase 2 study tests whether combining Baduanjin (a guided mind-body movement) with neuromodulation can improve knee osteoarthritis symptoms and function. It compares education-based stretching/control and uses MRI scanning as part of the research.
Charlestown, MassachusettsAges 45–75 - NCT05855369RecruitingPhase 2/Phase 3
Smell training plus brain stimulation for long COVID smell loss
This study tests whether a combination of smell training and a type of nerve stimulation can improve persistent smell problems after COVID. It is meant for people who had normal smell before COVID and still struggle with smell changes months later.
Charleston, South CarolinaAges 18–65 - NCT05997030Recruiting
Gentle Ultrasound for Alzheimer's Memory Problems
This study tests whether gentle, low-intensity ultrasound waves focused on certain brain areas can help people with early memory loss from Alzheimer's disease. It is a non-invasive treatment that might improve brain function without surgery.
Morgantown, West VirginiaAges 45–85 - NCT06000592Recruiting
Spinal stimulation to stabilize blood pressure after spinal cord injury
This trial tests whether a non-invasive device that sends gentle electrical pulses to the spinal cord can help people with a recent spinal cord injury keep their blood pressure steady. It's designed for those who experience low blood pressure when sitting or standing, which can cause dizziness or fainting.
New York, New YorkAges 14–100 - NCT06042517Recruiting
Ultrasound Nerve Stimulation for Diabetes
This study tests whether focused ultrasound can help people with type 2 diabetes by gently stimulating nerves. It may offer a new way to improve glucose control without medication.
New Haven, ConnecticutAges 18–80 - NCT06072703Recruiting
Brain stimulation for bladder control in MS
This study tests whether a type of brain stimulation can improve bladder control in women with multiple sclerosis. If you have bladder symptoms like urgency or frequent urination, this trial may help find new ways to manage them.
Houston, TexasAges 18 years+ - NCT06129890Recruiting
Brain stimulation for nerve pain and depression
This trial tests whether a noninvasive brain stimulation technique (rTMS) can help people with long-term nerve pain who also have depression. It aims to see if this treatment can reduce pain and improve mood.
Saint-EtienneAges 18–85 - NCT06226220Recruiting
Nerve test for bladder device success in women
This study tests how well a short, in-office nerve evaluation (PNE) predicts the success of sacral neuromodulation—a treatment that uses mild electrical pulses to calm bladder nerves. It is for women with urgency leaking or very frequent urination.
Chicago, IllinoisAges 18 years+ - NCT06272279Recruiting
Spinal Stimulation for Spinal Cord Injury
This study is testing a new way to use spinal cord stimulation to help people with spinal cord injuries. The goal is to see if it can improve movement or other functions.
Winnipeg, ManitobaAges 18–65 - NCT06274021RecruitingEarly Phase 1
Brain stimulation to reduce leg stiffness after spinal cord injury
This study tests a non-invasive brain stimulation technique (like a gentle magnetic pulse) to see if it can reduce muscle stiffness and spasms in the legs after a spinal cord injury. It may be a good option if you have ongoing leg stiffness and want a drug-free approach.
Jackson, MississippiAges 18 years+ - NCT06282406Recruiting
Brain stimulation guided by pupil size for hand recovery after stroke
This study tests a noninvasive (no surgery) brain stimulation technique guided by your pupil size to help improve hand function after a stroke. It is for people who had a single stroke at least 6 months ago and still have hand weakness.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06308484Recruiting
Mindfulness and brain stimulation for alcohol recovery
This trial tests if combining a non-invasive brain stimulation technique (like a mild electrical current) with mindfulness training can help people with alcohol dependence stay sober. If you recently stopped drinking and meet the health requirements, you may be able to join.
Berlin, State of BerlinAges 18–70 - NCT06345963Recruiting
Brain stimulation to improve connectivity in schizophrenia
This study tests if brain stimulation can improve how different brain regions communicate in people with schizophrenia. It may help improve thinking and daily function.
Houston, TexasAges 18–60 - NCT06361160Recruiting
Brain stimulation for treatment-resistant voices in schizophrenia
This trial tests a brain stimulation treatment (rTMS) to help reduce the frequency and intensity of voices people with schizophrenia hear. It is for individuals who continue to hear voices frequently despite trying multiple medications.
ParisAges 18 years+ - NCT06367777Recruiting
Neck and back nerve stimulation for pain processing
This trial studies how electrical stimulation of nerves in the neck and upper back affects the way your body processes pain. It aims to help understand pain better, which could lead to new treatments.
BrusselsAges 18–40 - NCT06387914Recruiting
Deep brain stimulation for chronic stroke pain
This trial tests whether deep brain stimulation (using a device implanted in the brain) can help relieve severe, long-lasting pain caused by a stroke. It is for people who have tried other treatments without success.
Oxford, OxfordshireAges 21 years+ - NCT06388707RecruitingPhase 1/Phase 2
Ultrasound brain stimulation for drug-resistant epilepsy
This trial tests a low-intensity focused ultrasound device that aims to calm overactive brain areas causing seizures. It's for people whose seizures are not controlled by medication.
Palo Alto, CaliforniaAges 18 years+ - NCT06391086Recruiting
Focused ultrasound for arm recovery after recent stroke
This study tests if focused ultrasound (a noninvasive sound wave therapy) can help improve arm and hand movement after a recent stroke. It is for people whose stroke occurred within the last three months and who still have some arm weakness.
TaipeiAges 18 years+ - NCT06415591Recruiting
Nerve stimulation for fibromyalgia in veterans
This trial tests whether a mild ear nerve stimulation device can reduce pain for veterans with fibromyalgia. It also looks at how the brain changes with treatment using MRI scans for some participants.
Decatur, GeorgiaAges 18 years+ - NCT06449326Recruiting
Brain imaging and stimulation study for PTSD in veterans
This study uses brain scans and a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help reduce PTSD symptoms in veterans. You may be eligible if you have ongoing PTSD symptoms and are on stable medication.
Albuquerque, New MexicoAges 18–80 - NCT06467253Recruiting
Brain stimulation plus memory training for mild memory loss
This study tests two gentle brain stimulation methods combined with memory training for people with mild memory loss. It aims to help improve thinking and memory skills over 8 weeks at a psychiatric hospital in Mexico City.
Mexico CityAges 55–85
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Common questions
- Are there clinical trials for neuromodulation?
- Yes. Clin2 currently lists 202 recruiting neuromodulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuromodulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuromodulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.