Clinical trials
Neuroprotection clinical trials
Below are recruiting neuroprotection clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04664946Recruiting
Intra-arterial treatment for stroke when no reperfusion was given
This trial tests an “intra-arterial” approach (a treatment delivered through an artery to the brain) for people with ischemic stroke who were not given clot-busting therapy or a clot-removal procedure. It aims to improve neurological recovery when there wasn’t reperfusion therapy, including in cases where symptoms worsen soon after stroke.
ShenyangAges 18 years+ - NCT04664933Recruiting
Study to protect the brain during clot-removal stroke treatment
This trial tests a brain-protective approach given through an artery during treatment for an acute ischemic stroke when clot removal (endovascular therapy) is planned. It may help reduce brain injury related to the stroke and procedure.
ShenyangAges 18 years+ - NCT06550167Recruiting
Nano PSO for brain protection in substance users
This trial tests whether a supplement called Nano PSO can help protect the brain in people who have used methamphetamines, cocaine, and cannabis for at least three years. It looks at effects during the withdrawal period for men currently in residential treatment.
Guadalajara, JaliscoAges 18–50 - NCT06572085RecruitingPhase 4
Butylphthalide for brain protection after cardiac arrest
This trial tests a medicine called butylphthalide (NBP) to see if it helps protect the brain after a cardiac arrest. It is for adults who remained unconscious after their heart was restarted.
Beijing, Beijing MunicipalityAges 18–80 - NCT06992843Recruiting
Protecting the brain after cardiac arrest coma
This trial tests a set of treatments designed to protect the brain in people who remain unconscious after their heart restarts following a cardiac arrest. It may help improve recovery by preventing further brain injury.
Changsha, HunanAges 18–80 - NCT05426681RecruitingPhase 1
Glyburide to protect the spinal cord after injury
This Phase 1 trial tests whether glyburide, a drug used for blood sugar, can help protect nerve tissue after an acute spinal cord injury. It’s mainly focused on safety and early signs that the treatment might be beneficial for people with certain levels of spinal cord damage.
Lexington, KentuckyAges 18–80 - NCT07107477RecruitingPhase 3
Tailored therapy for preterm membrane rupture to prolong pregnancy
This trial tests a personalized treatment plan for people whose water breaks too early (before 34 weeks). The goal is to safely extend the pregnancy and improve health outcomes for both the parent and baby, while reducing the use of antibiotics.
BrnoAges 18 years+ - NCT07715864RecruitingPhase 2
Cannabis compounds for brain protection after concussion
This trial tests whether natural cannabis compounds can help protect the brain after a concussion in male contact-sport athletes. It requires you to be healthy, not a regular cannabis user, and free of certain medical conditions.
Regina, SaskatchewanAges 19–35 - NCT03347786RecruitingPhase 1/Phase 2
Verapamil to protect the brain after acute stroke
This trial tests whether verapamil, a common blood-pressure/heart medicine, can help protect the brain after an acute ischemic stroke. It may improve recovery outcomes by supporting the brain’s ability to heal, especially early after stroke symptoms begin.
Atlantic City, New JerseyAges 18–80 - NCT03910738RecruitingPhase 2
Testosterone treatment for nerve protection and myelin repair in MS
This Phase 2 study tests whether taking testosterone (for low testosterone levels) can help protect nerves and repair myelin in people with relapsing-remitting multiple sclerosis (MS). It may be most relevant if your MS is stable and you have low blood testosterone without current androgen treatment.
BesançonAges 18–55 - NCT04201964Recruiting
TNK treatment for stroke when blood flow didn’t reopen enough
This trial looks at giving a clot-busting medicine directly into the brain arteries (intra-arterial TNK) when a stroke procedure (thrombectomy) doesn’t reopen the blocked vessel enough. It aims to improve recovery by improving blood flow while checking for safety, especially bleeding risk.
ShenyangAges 18 years+ - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT05195658Recruiting
Stent vs standard treatment for acute carotid artery stroke
This trial studies whether placing a special device (a micronet-covered stent) can improve treatment of certain acute strokes caused by blockage at the carotid artery “bifurcation” (where the artery splits). It is meant for people who need an urgent, catheter-based procedure to open the blocked vessel.
KrakowAges 18 years+ - NCT05426044RecruitingPhase 2
Metformin to protect the optic nerve in glaucoma
This study tests whether metformin can slow damage to the optic nerve in people with glaucoma. It uses eye scans and vision tests to look for changes over time, aiming to help preserve sight.
Wong Chuk HangAges 18 years+ - NCT05651347RecruitingPhase 3
Melatonin in pregnancy to protect babies with slow growth
This trial studies whether taking melatonin during pregnancy can help protect the baby’s brain and organs in cases of poor fetal growth. It focuses on pregnancies at a specific gestational age with signs that the placenta may not be working well.
Camperdown, New South WalesAges 18 years+ - NCT05679739Recruiting
Caring for brain after cardiac arrest
This study tests a treatment approach aimed at protecting the brain and supporting better blood flow to the brain after a cardiac arrest. It may help some people who are in a coma right after the event recover more safely or with less brain injury.
SingaporeAges 21–79 - NCT05796401RecruitingPhase 3
Personalized care program for early psychosis outcomes
This trial tests whether a personalized care plan improves day-to-day functioning for people in the early stages of psychosis. It aims to see if adding structured support after a recent diagnosis can help you function better.
BrestAges 15–30 - NCT05854524Recruiting
Exercise program to protect the brain in Parkinson’s disease
This trial studies whether doing regular moderate aerobic exercise can help protect the brain in people with Parkinson’s disease. It also includes people without Parkinson’s to compare exercise effects, using fitness and safety screening to keep everyone safe.
Las Vegas, NevadaAges 30–85 - NCT05917717Recruiting
Test a care bundle for adults after witnessed cardiac arrest
This trial studies a “care bundle” approach using special devices to improve care after an out-of-hospital or witnessed cardiac arrest. It may help by standardizing emergency treatment for people right after their heart stops.
Southampton, EnglandAges 18–120 - NCT06294847RecruitingPhase 3
Ursodeoxycholic acid for better recovery after retinal detachment surgery
This trial tests if adding ursodeoxycholic acid (a bile acid medication) to standard surgery can protect the retina and improve vision after a retinal detachment. It's for people who need vitrectomy surgery and have a detached retina involving the macula.
ParisAges 18 years+ - NCT06353334RecruitingPhase 4
Butylphthalide for brain recovery after cardiac arrest
This trial tests if butylphthalide can improve brain function in people who have been resuscitated after a cardiac arrest. It may help reduce brain damage and improve recovery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06434571RecruitingPhase 2
Comparing two sleep treatments for people with MS
This trial tests if talking with a sleep coach by video is better than a web-based program for improving sleep, reducing fatigue, and protecting the brain in people with multiple sclerosis (MS). Both treatments focus on changing thoughts and habits around sleep.
Kansas City, KansasAges 18–65 - NCT06455514RecruitingPhase 1
Magnesium to protect the brain after cardiac arrest
This study tests if giving magnesium soon after a cardiac arrest can protect the brain and improve recovery. It is for adults who have been brought back to life after a heart stoppage.
New York, New YorkAges 18–85 - NCT06473207Recruiting
Can a blood pressure cuff protect the brain after cardiac arrest?
This trial tests if a special blood pressure cuff (like a tourniquet) placed on the leg can protect the brain after a cardiac arrest. It is for patients who are unconscious and on a breathing machine after their heart restarts.
Toulon, VarAges 18 years+
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Common questions
- Are there clinical trials for neuroprotection?
- Yes. Clin2 currently lists 35 recruiting neuroprotection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuroprotection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuroprotection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.