Clinical trials
Neuroprotection clinical trials
Below are recruiting neuroprotection clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04664946Recruiting
Intra-arterial treatment for stroke when no reperfusion was given
This trial tests an “intra-arterial” approach (a treatment delivered through an artery to the brain) for people with ischemic stroke who were not given clot-busting therapy or a clot-removal procedure. It aims to improve neurological recovery when there wasn’t reperfusion therapy, including in cases where symptoms worsen soon after stroke.
ShenyangAges 18 years+ - NCT06550167Recruiting
Nano PSO for brain protection in substance users
This trial tests whether a supplement called Nano PSO can help protect the brain in people who have used methamphetamines, cocaine, and cannabis for at least three years. It looks at effects during the withdrawal period for men currently in residential treatment.
Guadalajara, JaliscoAges 18–50 - NCT07455747Recruiting
Study of a new system for treating carotid artery disease
This study is testing a special system (ENROUTE Transcarotid Neuroprotection) used with a stent to treat narrowed carotid arteries, which can help prevent stroke. It looks at how well the system works in real medical settings.
St Louis, MissouriAges 18 years+ - NCT06572085RecruitingPhase 4
Butylphthalide for brain protection after cardiac arrest
This trial tests a medicine called butylphthalide (NBP) to see if it helps protect the brain after a cardiac arrest. It is for adults who remained unconscious after their heart was restarted.
Beijing, Beijing MunicipalityAges 18–80 - NCT06992843Recruiting
Protecting the brain after cardiac arrest coma
This trial tests a set of treatments designed to protect the brain in people who remain unconscious after their heart restarts following a cardiac arrest. It may help improve recovery by preventing further brain injury.
Changsha, HunanAges 18–80 - NCT04664933Recruiting
Study to protect the brain during clot-removal stroke treatment
This trial tests a brain-protective approach given through an artery during treatment for an acute ischemic stroke when clot removal (endovascular therapy) is planned. It may help reduce brain injury related to the stroke and procedure.
ShenyangAges 18 years+ - NCT05195658Recruiting
Stent vs standard treatment for acute carotid artery stroke
This trial studies whether placing a special device (a micronet-covered stent) can improve treatment of certain acute strokes caused by blockage at the carotid artery “bifurcation” (where the artery splits). It is meant for people who need an urgent, catheter-based procedure to open the blocked vessel.
KrakowAges 18 years+ - NCT04217421RecruitingPhase 3
Allopurinol for newborns needing heart surgery with bypass
This trial tests whether the medicine allopurinol can protect the brain and heart in newborns with serious congenital heart disease who need heart surgery soon after birth. It may help reduce injury during and around surgery that uses a heart-lung machine (cardiopulmonary bypass).
GroningenAges Up to 1 month - NCT05854524Recruiting
Exercise program to protect the brain in Parkinson’s disease
This trial studies whether doing regular moderate aerobic exercise can help protect the brain in people with Parkinson’s disease. It also includes people without Parkinson’s to compare exercise effects, using fitness and safety screening to keep everyone safe.
Las Vegas, NevadaAges 30–85 - NCT07715864RecruitingPhase 2
Cannabis compounds for brain protection after concussion
This trial tests whether natural cannabis compounds can help protect the brain after a concussion in male contact-sport athletes. It requires you to be healthy, not a regular cannabis user, and free of certain medical conditions.
Regina, SaskatchewanAges 19–35 - NCT07673913Recruiting
Blood markers and brain stimulation for hard-to-treat depression
This study is testing whether a new type of brain stimulation called intermittent theta burst stimulation (iTBS) can help people with treatment-resistant depression (depression that hasn't improved with standard medicines). It also looks at certain blood markers to see if they can predict how well someone will respond to this treatment.
Ankara, AnkaraAges 18–55 - NCT05917717Recruiting
Test a care bundle for adults after witnessed cardiac arrest
This trial studies a “care bundle” approach using special devices to improve care after an out-of-hospital or witnessed cardiac arrest. It may help by standardizing emergency treatment for people right after their heart stops.
Southampton, EnglandAges 18–120 - NCT06744361RecruitingPhase 2
Ketamine after cardiac arrest to protect the brain
This trial tests whether the sedative drug ketamine, given after a cardiac arrest, can help protect the brain. It's for people whose heart stopped outside the hospital due to a shockable rhythm and who needed a breathing tube placed by emergency responders.
CopenhagenAges 18 years+ - NCT06665113Recruiting
Ear nerve stimulation for early Parkinson's disease
This trial tests whether a non-invasive nerve stimulation device (taVNS) worn on the ear can protect brain cells and slow Parkinson's disease progression in early-stage patients. It is for people who have been diagnosed within the last 3 years and are already on standard medication.
Nanjing, JiangsuAges 55–75 - NCT03347786RecruitingPhase 1/Phase 2
Verapamil to protect the brain after acute stroke
This trial tests whether verapamil, a common blood-pressure/heart medicine, can help protect the brain after an acute ischemic stroke. It may improve recovery outcomes by supporting the brain’s ability to heal, especially early after stroke symptoms begin.
Atlantic City, New JerseyAges 18–80 - NCT06353334RecruitingPhase 4
Butylphthalide for brain recovery after cardiac arrest
This trial tests if butylphthalide can improve brain function in people who have been resuscitated after a cardiac arrest. It may help reduce brain damage and improve recovery.
Beijing, Beijing MunicipalityAges 18–80 - NCT07322965Recruiting
Citicoline and DHA supplement for glaucoma patients
This trial tests whether a dietary supplement (DHA + citicoline) can help protect vision in people with glaucoma. You may qualify if you have confirmed glaucoma in at least one eye and are between 50 and 75 years old.
Barcelona, BarcelonaAges 50–75 - NCT07181564Recruiting
Anesthesia methods and safety in sinus surgery
This trial compares different anesthesia techniques during functional endoscopic sinus surgery to see which one protects the brain best and improves the surgical field. It may help patients understand the safest approach for their procedure.
Pátrai, AchaiaAges 18–90 - NCT07167446RecruitingEarly Phase 1
CBD to prevent nerve damage from oxaliplatin in colorectal cancer
This trial tests if cannabidiol (CBD) can prevent nerve damage (neuropathy) caused by the chemotherapy drug oxaliplatin. If you have colorectal cancer that has spread or cannot be removed by surgery and you are about to start oxaliplatin, you may be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07135089RecruitingPhase 3
Tirofiban before clot removal for large artery stroke
This trial tests whether adding a clot-preventing medication called tirofiban before a mechanical clot removal procedure can improve recovery in people with a certain type of stroke. It's for those with a large artery blockage in the front part of the brain who are able to start the procedure within 12 hours.
Shenyang, LiaoningAges 18 years+ - NCT07119021RecruitingPhase 4
Ultra-early stroke treatment with neuroprotection and clot removal
This trial tests a new approach for treating acute ischemic stroke within 4.5 hours of symptoms starting. It combines a special mobile stroke unit that delivers early brain-protecting medicine with standard clot-busting or clot-removal procedures, to see if this can improve recovery.
BeijingAges 18–80 - NCT07107477RecruitingPhase 3
Tailored therapy for preterm membrane rupture to prolong pregnancy
This trial tests a personalized treatment plan for people whose water breaks too early (before 34 weeks). The goal is to safely extend the pregnancy and improve health outcomes for both the parent and baby, while reducing the use of antibiotics.
BrnoAges 18 years+ - NCT06294847RecruitingPhase 3
Ursodeoxycholic acid for better recovery after retinal detachment surgery
This trial tests if adding ursodeoxycholic acid (a bile acid medication) to standard surgery can protect the retina and improve vision after a retinal detachment. It's for people who need vitrectomy surgery and have a detached retina involving the macula.
ParisAges 18 years+ - NCT05679739Recruiting
Caring for brain after cardiac arrest
This study tests a treatment approach aimed at protecting the brain and supporting better blood flow to the brain after a cardiac arrest. It may help some people who are in a coma right after the event recover more safely or with less brain injury.
SingaporeAges 21–79
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Common questions
- Are there clinical trials for neuroprotection?
- Yes. Clin2 currently lists 37 recruiting neuroprotection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a neuroprotection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a neuroprotection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.