Clinical trials
Newly Diagnosed clinical trials
Below are recruiting newly diagnosed clinical trials, each written for real people, not researchers. We’re tracking 393 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07494565RecruitingPhase 2
Celecoxib plus standard chemo for CD5+ DLBCL
This trial tests whether adding celecoxib (an anti-inflammatory drug) to the standard R-CHOP chemotherapy regimen can improve outcomes for people with a specific, hard-to-treat type of diffuse large B-cell lymphoma (DLBCL) that is CD5-positive. It's for people who are newly diagnosed and have advanced disease.
Guangzhou, GuangdongAges 18–80 - NCT07490288Recruiting
Venetoclax, azacitidine, and mitoxantrone for new AML
This trial tests a combination of three drugs (venetoclax, azacitidine, and liposomal mitoxantrone) as a first treatment for people newly diagnosed with acute myeloid leukemia (AML). The goal is to see if this combination works better than standard care.
Tianjin, Tianjin MunicipalityAges 14–100 - NCT07488754Recruiting
Targeted radiation therapy for new glioma (grade 3-4)
This trial tests a new type of targeted radiation therapy for people with high-grade glioma (grade 3 or 4) that has not progressed after standard treatment. The therapy uses a radioactive substance attached to a protein that targets tumor cells, aiming to deliver radiation directly to the cancer.
Warsaw, PolandAges 18–80 - NCT07483879Recruiting
Organ Injury Biomarkers in Newly Diagnosed Type 1 Diabetes
This study looks at signs of acute organ injury in children newly diagnosed with type 1 diabetes. It aims to understand how the body reacts to diabetes and its treatment, which could help improve care for kids like yours.
Thessaloniki, Central MakedoniaAges 2–16 - NCT07485049RecruitingEarly Phase 1
BGB-58067 for newly diagnosed glioblastoma with MTAP deletion
This early-stage trial tests an experimental drug (BGB-58067) for people with a newly diagnosed glioblastoma that has a specific gene deletion (MTAP). It aims to see if the drug can shrink the tumor or slow its growth.
Phoenix, ArizonaAges 18 years+ - NCT07477587RecruitingPhase 1
Comparing two myeloma treatments for new patients
This trial tests a new drug combination (HLX15-SC) against an approved treatment (DARZALEX FASPRO) along with lenalidomide and dexamethasone for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant.
Springdale, ArkansasAges 18 years+ - NCT07480265Recruiting
Homocysteine and early heart function in new high blood pressure
This study looks at a substance in your blood called homocysteine and how it affects the early filling of your heart's main pumping chamber. It may help doctors understand heart risks in people newly diagnosed with high blood pressure.
Konya, MeramAges 18 years+ - NCT07476794RecruitingPhase 2
Daily temozolomide for elderly patients with newly diagnosed brain cancer
This trial tests a daily chemo drug (temozolomide) in patients aged 65 or older with a specific type of aggressive brain cancer that has a certain genetic marker. It aims to see if this daily schedule works well after initial radiation and chemo.
Toronto, OntarioAges 65 years+ - NCT07466316RecruitingPhase 3
Comparing chemo schedules for intermediate-risk rhabdomyosarcoma
This trial compares two different chemotherapy schedules for children and young adults with intermediate-risk rhabdomyosarcoma (a type of muscle cancer). One group gets a higher dose of chemotherapy over a shorter period, while the other gets a lower dose plus maintenance therapy for a longer time. The goal is to see which approach works better.
Birmingham, AlabamaAges Up to 50 years - NCT07465796Recruiting
Testing a new device during brain tumor surgery
This trial is testing a new tool called the CIPHER System during brain surgery for people with a newly diagnosed glioma. It looks at how well the tool works and how safe it is when used during the procedure.
Melbourne, VictoriaAges 18–75 - NCT07453082Recruiting
A study on miRNA371 for newly diagnosed germ cell tumors
This study is looking at a new marker called miRNA371 in people newly diagnosed with germ cell tumors. The goal is to see if it can help predict relapse and guide treatment decisions.
Candiolo, TurinAges 18 years+ - NCT07452458RecruitingPhase 3
Pulsed vs standard radiation for newly diagnosed glioblastoma
This trial tests a new way of giving radiation therapy (pulsed) compared to standard radiation for people with a specific type of glioblastoma (IDH wildtype, MGMT unmethylated). The goal is to see if the pulsed approach helps with thinking and memory while still treating the tumor.
Irvine, CaliforniaAges 18 years+ - NCT06805669Recruiting
Early palliative care for advanced soft tissue sarcoma
This study tests whether adding palliative care early on to standard cancer treatment improves quality of life for people newly diagnosed with advanced or metastatic soft tissue sarcoma.
Toronto, OntarioAges 18 years+ - NCT07439172RecruitingPhase 2
Chemotherapy before radiation for newly diagnosed brain tumors
This trial tests giving a chemotherapy drug called temozolomide before radiation therapy to people with a newly diagnosed high-grade brain tumor. The goal is to see if this approach can help control the tumor better.
Camden, New JerseyAges 18–80 - NCT06810791RecruitingPhase 3
Comparing Chemotherapy Combos for High-Risk AML
This trial compares three chemotherapy combinations (HVA vs IA/DA or VA) for people with newly diagnosed high-risk acute myeloid leukemia (AML). It aims to find which treatment works better.
Guangzhou, GuangdongAges 18 years+ - NCT07428993RecruitingPhase 2
CAR T-Cell Therapy for High-Risk Osteosarcoma
This trial tests a new type of cell therapy called B7-H3 CAR T cells for children and young adults with high-risk osteosarcoma that hasn't spread or worsened after standard chemotherapy. The treatment uses your own immune cells that are modified to attack a protein (B7-H3) found on cancer cells.
Memphis, TennesseeAges Up to 21 years - NCT07415681RecruitingPhase 2
Photon vs. Proton Radiation for New Gynecologic Cancers
This trial compares two types of radiation (standard photon vs. newer proton) for people with newly diagnosed endometrial or cervical cancer. It aims to see if proton therapy reduces side effects while controlling the cancer just as well.
Baltimore, MarylandAges 18 years+ - NCT07409454RecruitingPhase 2
Post-transplant treatment for multiple myeloma with a bispecific antibody
This trial tests a drug that helps your immune system target and kill myeloma cells after a stem cell transplant. It is for people with newly diagnosed multiple myeloma who still have minimal residual disease (small amounts of cancer) after their first transplant.
TianjinAges 18 years+ - NCT07410520RecruitingPhase 2
New drug combo for brain lymphoma
This trial tests a combination of three drugs (rituximab, methotrexate, and orelabrutinib) plus a PD-1 inhibitor for newly diagnosed or relapsed central nervous system lymphoma. The goal is to see if this new combination can improve outcomes for patients with this rare type of lymphoma.
Nanjing, JiangsuAges 18 years+ - NCT07406282Recruiting
Darolutamide for new prostate cancer that spread
This study looks at how well darolutamide and similar drugs work for men whose prostate cancer has just spread to other parts of the body. It aims to understand real-world outcomes in urology clinics.
Cleveland, OhioAges 18 years+ - NCT03827382Recruiting
Bicycle exercise and lifestyle changes for new type 2 diabetes
This trial studies whether a structured bicycle exercise and lifestyle program can help people who were recently diagnosed with type 2 diabetes. It may be especially relevant if your blood sugar levels are still above a certain threshold.
Basel, Canton of Basel-CityAges 18 years+ - NCT06361329RecruitingPhase 3
Comparing new drug combo to standard chemo for ETP-ALL
This trial compares a new combination of drugs (venetoclax plus chemotherapy) to standard chemotherapy for people newly diagnosed with a rare type of T-cell leukemia called ETP-ALL. The goal is to see if the new regimen works better.
Hangzhou, ZhejiangAges 14–75 - NCT05603884RecruitingPhase 2
New treatment plan for older adults with newly diagnosed AML
This trial studies a two-part chemotherapy plan for older adults newly diagnosed with acute myeloid leukemia (AML) who can’t take the usual standard induction treatment. It aims to improve how well treatment works while taking into account age and other health conditions.
Xiamen, FujianAges 60 years+ - NCT06151080RecruitingPhase 2
Lenalidomide plus G-CHOP for new DLBCL with follicular lymphoma
This study tests combining the drug lenalidomide with a standard chemotherapy regimen (G-CHOP) for people newly diagnosed with a specific type of lymphoma that has both aggressive and slow-growing parts. The goal is to see if this combination works better than standard treatment alone.
Xiamen, FujianAges 18–70
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Common questions
- Are there clinical trials for newly diagnosed?
- Yes. Clin2 currently lists 393 recruiting newly diagnosed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a newly diagnosed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a newly diagnosed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.