Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 493 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07557953RecruitingPhase 1
How cagrilintide affects hunger and eating in overweight adults
This early-stage study tests a new medication called cagrilintide to see how it influences appetite and food intake in adults with overweight or obesity. Researchers want to understand if this drug could help people feel fuller and eat less.
BerlinAges 18–64 - NCT07437079RecruitingPhase 1
Testing a new weight-loss medicine in healthy people
This study tests a new medicine (NNC6989-0001) for people who are overweight or have obesity. It checks if the medicine is safe and how the body handles it. If eligible, you would receive the study drug and be monitored closely.
Lenexa, KansasAges 18–55 - NCT07411560RecruitingPhase 1
Weekly injections for stomach side effects in overweight people
This study tests two weekly hormone injections (GIP and amylin) to see how they affect stomach-related side effects in people who are overweight or obese. Researchers want to understand if these hormones can help manage weight or related symptoms.
Harrow, MiddlesexAges 18–64 - NCT07395687RecruitingPhase 2
Study of UBT251 for people with overweight or obesity
This trial tests different doses of UBT251, a new medicine, to see how well it helps people lose weight. It may be an option if you have overweight or obesity and meet certain age and BMI requirements.
Cypress, CaliforniaAges 18–65 - NCT07331974Recruiting
A trial of Akkermansia for weight loss in overweight adults
This trial tests a supplement containing Akkermansia bacteria to see if it helps adults who are overweight or obese lose weight. It may be an option if you have not taken weight loss medications recently and are already trying to manage your weight with diet and exercise.
Guangzhou, GuangdongAges 18–60 - NCT07245771RecruitingPhase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide
This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).
Melbourne, VictoriaAges 18–65 - NCT07075146RecruitingPhase 3
Comparing two HIV treatments for people with overweight or obesity
This trial compares two different daily pill combinations for people newly starting HIV treatment who are overweight or have obesity. It aims to see which one works better for controlling the virus and managing weight.
Mexico CityAges 18–70 - NCT06143956RecruitingPhase 2
Weight loss treatments for adults with obesity
This clinical trial tests new treatments for adults who are overweight or have obesity. The goal is to help people lose weight and improve their health.
Chandler, ArizonaAges 18–75 - NCT07843498RecruitingPhase 3
Testing a new weight-loss medicine in adults with overweight or obesity
This study tests a new medication called petrelintide to see how well it helps people lose weight and improve their health. It's for adults with overweight or obesity who have struggled to lose weight with diet alone.
Anniston, AlabamaAges 18 years+ - NCT07796971Recruiting
Exercise in low vs normal oxygen for weight and gut health
This study tests two exercise programs—one in low oxygen, one in normal oxygen—to see which is better at reducing body fat and improving gut health in adults aged 50–75 who are overweight or obese. You'll do high-intensity interval training (short bursts of intense exercise) and we'll monitor your results over time.
Bellerive-sur-AllierAges 50–75 - NCT07784270RecruitingPhase 3
Weight loss injection for adults with type 2 diabetes and overweight
This study tests a new injected medicine that may help people with type 2 diabetes and overweight or obesity lose weight. The trial will see how well it works and if it is safe compared to a placebo.
Fairhope, AlabamaAges 18 years+ - NCT06704581RecruitingPhase 3
Study of BGM0504 injection for weight loss
This study tests a new weekly injection (BGM0504) to help people with obesity or overweight lose weight. It may be an option if you have not had success with diet and exercise alone and meet certain health criteria.
Beijing, Beijing MunicipalityAges 18–65 - NCT07594093RecruitingPhase 1
A study of REGN20934 for adults with overweight or obesity
This trial tests a new medication, REGN20934, to see how safe it is and how it works in the body for adults who are overweight or have obesity. It may help if you are looking for new treatment options.
Glendale, CaliforniaAges 18–65 - NCT07550816RecruitingPhase 1
Safety study of ZT002 injection in overweight adults
This study tests how a new diabetes medicine called ZT002 works in the body and whether it interacts safely with other common medications. Researchers will monitor healthy volunteers who are overweight to understand the medicine's safety and effectiveness.
Chengdu, SichuanAges 18–45 - NCT07501377Recruiting
Diet and brain health study for women in menopause with overweight
This trial tests whether a diet rich in fiber and plant compounds (polyphenols) can reduce brain inflammation in perimenopausal women who are overweight. If you're in early menopause and have some inflammation, this study may show how diet affects your brain health.
Leipzig, SaxonyAges 35–60 - NCT07487376RecruitingPhase 1
A single-dose study of IBIO-600 in healthy overweight or obese adults
This trial tests a single dose of an experimental treatment called IBIO-600 to see if it's safe and how it works in overweight or obese adults. It's for people who are generally healthy and have a stable weight, without diabetes.
Bayswater, VictoriaAges 18–65 - NCT07465965RecruitingPhase 1
Weight loss study of semaglutide nasal spray in overweight or obese adults
This study tests a nasal spray containing semaglutide (a GLP-1 receptor agonist) to see if it helps adults who are overweight or obese lose weight. It may be an option if you have a BMI between 27 and 35 and have not used other weight loss medications recently.
Secaucus, New JerseyAges 18–65 - NCT07243171RecruitingPhase 1/Phase 2
Oral Ecnoglutide for overweight or obesity
This trial tests an oral medication called Ecnoglutide to help people with overweight or obesity lose weight. It is for Chinese adults who are not diabetic and have a stable weight.
Beijing, Beijing MunicipalityAges 18–65 - NCT06996431Enrolling by invitation
Weight loss program with mobile health support
This study tests a new way to help adults lose weight using a smartphone app and health coaching. You might qualify if you are overweight, live in Hong Kong, speak Chinese, and can walk without help.
Hong KongAges 18 years+ - NCT06868862Recruiting
Exercise and fat loss in young women with overweight or obesity
This study compares two types of exercise (short bursts of intense activity vs. moderate continuous activity) to see which is better for fat loss in young women who have overweight or obesity. The exercises have the same total energy used, so the results can show which type might be more helpful for weight management.
São Paulo, São PauloAges 20–45 - NCT06842186RecruitingPhase 1/Phase 2
Study of WVE-007 for overweight or obesity
This trial tests an experimental drug called WVE-007 for people who are overweight or have obesity. It aims to help with weight loss and is looking at both a group without diabetes and a group with prediabetes or type 2 diabetes.
Baltimore, MarylandAges 18–60 - NCT06830343RecruitingPhase 1
Safety study of SYH9017 for overweight and obesity
This study tests a new medication called SYH9017 for people who are overweight or have obesity. It aims to see how safe the drug is, how well it is tolerated, and how the body processes it. Participants will receive either the drug or a placebo and be monitored closely.
Beijing, Beijing MunicipalityAges 18–60 - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Tucson, ArizonaAges 6–17 - NCT06636773Recruiting
Aerobic vs Aerobic Plus Yoga for Weight Loss
This study compares two exercise programs — aerobic exercise alone versus aerobic exercise combined with yoga — to see which helps adults with overweight or obesity lose weight. You would need to follow a diet plan and attend regular exercise sessions at the University of Kansas Medical Center.
Kansas City, KansasAges 18 years+
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 493 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.