Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 494 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06935513Recruiting
Wearable devices for stroke prevention
This trial tests if using a smart wearable device can help people at high risk for stroke stay active and reduce their risk. You may be able to join if you have certain health conditions or habits that increase your stroke risk.
Nantong, JiangsuAges 30 years+ - NCT07150975RecruitingPhase 3
Study comparing new weekly injection vs. Wegovy for weight loss
This trial tests a new weekly injection called GZR18 against the existing drug Wegovy for weight loss in adults who are overweight or obese. It aims to see which is more effective and safe for helping people lose weight and improve related health conditions.
BeijingAges 18 years+ - NCT07136714RecruitingPhase 4
Semaglutide for depression in people with overweight
This study tests whether a weekly injection of semaglutide (a medication used for weight loss and diabetes) can help reduce symptoms of depression in people who have major depressive disorder and are overweight or obese.
Hillerød, DenmarkAges 18–65 - NCT07128888RecruitingPhase 1
GZR18 injection effects on stomach emptying and drug interactions
This trial tests how a new injectable drug, GZR18, affects how fast your stomach empties and how it interacts with other medicines. It is for obese Chinese adults who want to join a research study.
BeijingAges 18–50 - NCT07123779RecruitingPhase 1/Phase 2
Study of a new drug for heart failure with pulmonary hypertension
This study tests an investigational drug (HS235) for people who have both heart failure with preserved ejection fraction and a type of pulmonary hypertension that can happen with it. The goal is to see if the drug can improve symptoms and quality of life.
Kansas City, MissouriAges 18 years+ - NCT07114419RecruitingPhase 2
New weekly injection for weight loss in overweight or obesity
This study tests a new weekly injection, efsubaglutide alfa (a GLP-1 drug), for helping people with overweight or obesity lose weight. It is for people who have not been able to lose weight with diet and exercise alone and do not have other serious health conditions.
BrookvaleAges 18–75 - NCT07095543Recruiting
Plant-based weight loss through online program
This study tests an online weight loss program based on a plant-based diet. You may be able to join if you live in the U.S., are overweight, can travel to Washington DC for a body scan, and are not using weight loss medications.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07085923Recruiting
Heart health study for people with mental illness
This study tests a program to improve heart health in people with schizophrenia or bipolar disorder who take antipsychotic medication or lithium and have a high body weight. The goal is to help reduce heart disease risk.
OsloAges 25–70 - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT06897241Recruiting
How different starches affect your metabolism
This study tests how your body responds to different types of starch (quick, slow, and resistant). You will follow special diet plans and use monitoring devices to understand your personal metabolic reactions.
Gothenburg, Västra Götaland CountyAges 30–75 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT07075341Recruiting
Healthy living beyond weight study
This study tests whether a program focused on healthy eating and activity can help people manage their weight or maintain a healthy weight after treatment. It may be right for you if you are an adult concerned about your weight or health.
Dallas, TexasAges 18 years+ - NCT07065643Recruiting
Calorie restriction study for healthy overweight adults
This study looks at how sex hormones affect the benefits of a low-calorie diet in men and women of different ages. If you are a healthy overweight adult, the study may help understand how hormones and age influence weight loss results.
AberdeenAges 18–65 - NCT05301413RecruitingPhase 2
Diabetes prevention program tailored for Black adults at risk
This Phase 2 study tests a diabetes-prevention program designed for Black/African American adults, focusing on social factors that can affect health and weight. It aims to help participants lower their chances of developing type 2 diabetes through structured education and tracking.
Kansas City, MissouriAges 18 years+ - NCT07044570Recruiting
Examining attitudes in physical activity engagement
This trial tests if a program can help people who are not very active start and stick with a physical activity routine. Participants will wear a study-provided smartwatch to track their activity and answer brief surveys.
Los Angeles, CaliforniaAges 18 years+ - NCT07053644Recruiting
Fresh foods for families: a healthy eating program
This study helps families with children ages 8 to 12 eat healthier by providing fresh food resources and education. It is designed for English-speaking parents or caregivers living in specific neighborhoods.
Tampa, FloridaAges 18 years+ - NCT07043166Recruiting
Heart, kidney, and metabolic health study in Shanghai
This study looks at the link between heart, kidney, and metabolic health in adults living in Shanghai. It follows people who were part of an earlier health study to see how their health changes over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06994338RecruitingPhase 2
Tirzepatide for alcohol use disorder
This study tests whether a medication called tirzepatide (a once-weekly injection) can help people reduce their alcohol consumption. It is for people who drink heavily, have a high BMI, and are actively seeking help to drink less.
Los Angeles, CaliforniaAges 21–65 - NCT06994923Recruiting
Weight management study for college students
This pilot study tests a weight management program designed for college students. If you have a BMI of 25 or higher and are a student at this college, you may be able to join and get support with healthy eating and activity habits.
Providence, Rhode IslandAges 18–29 - NCT06976112Recruiting
Lean pork and heart health in perimenopause
This study tests whether adding lean pork to your diet can improve blood vessel function during perimenopause. You may be eligible if you are a woman between 40 and 55, have irregular periods, and have high blood pressure but not diabetes.
Baton Rouge, LouisianaAges 40–55 - NCT06953232Recruiting
Protein drink for heart and brain in midlife women
This study tests a special protein drink (whey with milk fat globule membrane) to see if it helps your heart and brain after a high-fat breakfast. It might help you if you are a postmenopausal woman at moderate risk for heart disease.
Loughborough, LeicestershireAges 50–75 - NCT06961591Recruiting
Cooking skills for long-term weight loss in young adults with ID
This program teaches cooking skills to help young adults with intellectual disabilities lose weight and keep it off for 2 years. You’ll learn to prepare healthier meals with support from a family member or caregiver.
Kansas City, KansasAges 18–35 - NCT06952348Recruiting
Stair climbing vs brisk walking for blood pressure
This study tests whether climbing stairs regularly can lower blood pressure better than brisk walking. It is for people who have high blood pressure, are overweight, and are not very active right now.
StockholmAges 35 years+ - NCT06949280Recruiting
Peanuts, weight loss, and bone health study
This study tests whether eating peanuts daily during weight loss affects bone health in adults aged 50 to 75.
New Brunswick, New JerseyAges 50–75
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 494 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.