Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 486 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06493084RecruitingPhase 1
Testing LAE102 in healthy and overweight adults
This study tests a new medicine called LAE102 in two groups: healthy volunteers and people who are overweight or obese. The goal is to see if it is safe and how the body processes it.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75 - NCT06526273Recruiting
PILI 'Āina Household Program
This study is for Native Hawaiian adults living in homestead communities who are overweight or have health conditions like diabetes, high blood pressure, or high cholesterol. It looks at a household-based program to help you and your family make healthier lifestyle changes together.
Honolulu, HawaiiAges 18 years+ - NCT06526650Recruiting
Cooking demos for Native Hawaiian adults with diabetes or heart risks
This trial tests if cooking demonstrations can help Native Hawaiian adults with conditions like type 2 diabetes, pre-diabetes, high blood pressure, or high cholesterol improve their health. You'd learn healthy cooking and be encouraged to do moderate activity like brisk walking.
Honolulu, HawaiiAges 18 years+ - NCT06555393RecruitingPhase 1
Egg protein health effect pilot study
This study looks at whether a protein from eggs can help people who are at risk for diabetes or who have type 2 diabetes. Participants will eat a special egg product and have their health checked. It compares how healthy people and those with or at risk for diabetes respond.
Edmonton, AlbertaAges 18–70 - NCT06570642Recruiting
Study on emotions and physical activity
This study looks at how emotions affect your desire to be active. You'll wear a Fitbit smartwatch and answer short surveys to help researchers understand what helps people start and stick with physical activity.
Los Angeles, CaliforniaAges 18 years+ - NCT06588218Recruiting
Watermelon for gut and heart health in young adults
This study is testing whether eating watermelon every day for 4 weeks can improve gut health and heart health in young adults. If you are overweight and between 18 and 30, you may be able to join.
Tallahassee, FloridaAges 18–30 - NCT06594796Recruiting
Lifestyle program for back pain and weight
This trial tests a combined exercise and lifestyle program for people with long-lasting low back pain who are overweight or have obesity. The program is delivered by physical therapists and aims to improve physical function and reduce pain.
AmsterdamAges 18 years+ - NCT06596265Recruiting
Fit2Lead Study: Community park programs for teen health
This study looks at how community park programs can help improve health among teens. It uses data from teenagers who were already part of a larger program called Fit2Lead in Miami-Dade County.
Miami, FloridaAges 12–17 - NCT06600100Recruiting
Inhibitory control training for weight management
This trial tests an online training program designed to improve your ability to resist cravings and make healthier choices. It may help you lose weight by strengthening the part of your brain that controls impulses.
GranadaAges 18–60 - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06623669RecruitingPhase 2
Mobile program to reduce pain and improve health in older adults
This trial tests a mobile program to help reduce pain and improve health in older adults with knee or hip arthritis who are not very active. The program involves exercise and may help with weight management.
Winston-Salem, North CarolinaAges 65 years+ - NCT06653530Recruiting
Thread embedding acupuncture for weight loss
This trial tests a type of acupuncture called thread embedding to help with weight loss. It's for people who haven't had success with diet and exercise alone and have a higher body weight or weight-related health issues.
Beijing, Beijing MunicipalityAges 18–75 - NCT06668077Recruiting
Impulse control training and brain stimulation for weight loss
This study tests whether a computer-based training to improve impulse control, combined with a gentle brain stimulation technique (called iTBS), can help people with excess weight. It also looks at how these treatments affect the brain using MRI scans.
GranadaAges 18–60 - NCT06705400Recruiting
The Bloom Study: A Healthy Start for Mom and Baby
This study follows first-time mothers and their babies from pregnancy to early childhood, using digital tools to support a healthy start. It aims to learn how to improve health and well-being for both mom and baby.
CopenhagenAges birth–6 months - NCT04297592Enrolling by invitationPhase 4
Antibiotics to prevent infection after hip or knee replacement
This trial studies whether giving antibiotics before and/or after surgery can lower the chance of a serious joint infection after elective hip or knee replacement. It’s aimed at people at higher risk for infection.
Iowa City, IowaAges 18–99 - NCT06724172Recruiting
Comparing health programs for pregnant mothers from diverse backgrounds
This study tests two different health programs for pregnant women to see which one helps mothers and babies more. You may join if you are early in your pregnancy, identify as Black, Hispanic, or have Medicaid, and speak English or Spanish.
Palo Alto, CaliforniaAges 18 years+ - NCT06724406Recruiting
Family-centered weight loss for Black adults
This trial tests a weight loss program for Black adults and a family partner. You and a family member work together to lose weight with support from a smartphone or computer.
Chapel Hill, North CarolinaAges 18–75 - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+ - NCT06847399RecruitingPhase 2
Tirzepatide for Binge Eating Disorder
This trial tests if tirzepatide (a weekly injection) can help reduce binge eating compared to a placebo or another medication (lisdexamfetamine dimesylate). It may be a good fit for people with moderate or severe binge eating disorder who also have a high body weight.
Baltimore, MarylandAges 18 years+ - NCT06853288Recruiting
How processed foods affect energy from food
This study looks at how eating ultra-processed foods changes how much energy your body takes from food. If you have a BMI between 30 and 40 and are otherwise healthy, you may help scientists learn more about weight and metabolism.
New York, New YorkAges 25 years+ - NCT06853652Recruiting
Protein needs after weight-loss surgery
This study looks at how much protein you need after Roux-en-Y gastric bypass (RYGB) surgery. It will help find the right amount of protein to keep your body healthy after weight-loss surgery.
LeuvenAges 18–65 - NCT06855784Recruiting
Time-Restricted Eating for Menopause and Breast Cancer
This study tests if time-restricted eating (eating only during a set window each day) can help women with menopausal symptoms, including those who have had hormone-sensitive breast cancer and are on hormone-blocking therapy.
Geneva, Canton of GenevaAges 45–60
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 486 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.