Clinical trials
Obesity & Overweight clinical trials
Below are recruiting obesity & overweight clinical trials, each written for real people, not researchers. We’re tracking 494 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06938269RecruitingPhase 1
Study of MWN109 tablets in healthy adults
This trial tests a new tablet called MWN109 in healthy adults to see how safe it is and how the body handles it. It has two parts: one for people with a wide range of body weights, and another specifically for people with higher body weight. The results will help guide future studies.
Adelaide, South AustraliaAges 18–60 - NCT06923644Recruiting
Personalized nutrition plan to prevent metabolic disease
This study tests whether a personalized nutrition plan based on your unique metabolism can help prevent chronic metabolic diseases like type 2 diabetes. You will follow a tailored diet and have your health monitored over time.
MaastrichtAges 40–75 - NCT06923735Enrolling by invitation
Nutrition app pilot for employee health checks
This pilot study tests a nutrition app to help employees manage conditions like high cholesterol, high blood pressure, weight issues, or type 2 diabetes. It is part of your regular occupational health check or dietitian visit.
KuopioAges 18–75 - NCT06570642Recruiting
Study on emotions and physical activity
This study looks at how emotions affect your desire to be active. You'll wear a Fitbit smartwatch and answer short surveys to help researchers understand what helps people start and stick with physical activity.
Los Angeles, CaliforniaAges 18 years+ - NCT06847399RecruitingPhase 2
Tirzepatide for Binge Eating Disorder
This trial tests if tirzepatide (a weekly injection) can help reduce binge eating compared to a placebo or another medication (lisdexamfetamine dimesylate). It may be a good fit for people with moderate or severe binge eating disorder who also have a high body weight.
Baltimore, MarylandAges 18 years+ - NCT06855784Recruiting
Time-Restricted Eating for Menopause and Breast Cancer
This study tests if time-restricted eating (eating only during a set window each day) can help women with menopausal symptoms, including those who have had hormone-sensitive breast cancer and are on hormone-blocking therapy.
Geneva, Canton of GenevaAges 45–60 - NCT06853288Recruiting
How processed foods affect energy from food
This study looks at how eating ultra-processed foods changes how much energy your body takes from food. If you have a BMI between 30 and 40 and are otherwise healthy, you may help scientists learn more about weight and metabolism.
New York, New YorkAges 25 years+ - NCT06845345Enrolling by invitationPhase 4
Can a special diet or pills help liver health?
This study compares two treatments for liver scarring in people with overweight or related health issues. One group follows a special diet with restricted eating times, while the other takes a combination of two medications (naltrexone and bupropion). It aims to see which approach better improves liver fibrosis.
RotterdamAges 18–75 - NCT06824974Recruiting
Time-restricted eating for liver disease or cancer
This study tests whether combining time-restricted eating with healthy eating helps people with metabolic liver disease, cirrhosis, or early-stage liver cancer. If you are overweight and currently fast less than 12 hours at night, this diet approach might improve your health.
La Jolla, CaliforniaAges 18 years+ - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT06724172Recruiting
Comparing health programs for pregnant mothers from diverse backgrounds
This study tests two different health programs for pregnant women to see which one helps mothers and babies more. You may join if you are early in your pregnancy, identify as Black, Hispanic, or have Medicaid, and speak English or Spanish.
Palo Alto, CaliforniaAges 18 years+ - NCT06724406Recruiting
Family weight loss program for Black adults
This study tests a family-centered weight loss program for Black adults and their family members. You and a family member or partner will work together to lose weight and improve health.
Chapel Hill, North CarolinaAges 18–75 - NCT06705400Recruiting
The Bloom Study: A Healthy Start for Mom and Baby
This study follows first-time mothers and their babies from pregnancy to early childhood, using digital tools to support a healthy start. It aims to learn how to improve health and well-being for both mom and baby.
CopenhagenAges birth–6 months - NCT06640179Recruiting
Lifestyle program for kidney transplant recipients
This study tests a diet and exercise program for people who recently received a kidney transplant. It aims to see if the program is safe and helpful for improving health after transplant.
Kansas City, KansasAges 18 years+ - NCT06623669RecruitingPhase 2
Mobile program to reduce pain and improve health in older adults
This trial tests a mobile program to help reduce pain and improve health in older adults with knee or hip arthritis who are not very active. The program involves exercise and may help with weight management.
Winston-Salem, North CarolinaAges 65 years+ - NCT06596265Recruiting
Fit2Lead Study: Community park programs for teen health
This study looks at how community park programs can help improve health among teens. It uses data from teenagers who were already part of a larger program called Fit2Lead in Miami-Dade County.
Miami, FloridaAges 12–17 - NCT06588218Recruiting
Watermelon for gut and heart health in young adults
This study is testing whether eating watermelon every day for 4 weeks can improve gut health and heart health in young adults. If you are overweight and between 18 and 30, you may be able to join.
Tallahassee, FloridaAges 18–30 - NCT06555393RecruitingPhase 1
Egg protein health effect pilot study
This study looks at whether a protein from eggs can help people who are at risk for diabetes or who have type 2 diabetes. Participants will eat a special egg product and have their health checked. It compares how healthy people and those with or at risk for diabetes respond.
Edmonton, AlbertaAges 18–70 - NCT06521021Recruiting
Choice to avoid or resist eating
This study tests two ways to help people lose weight: making a choice to eat less or to resist cravings. You will learn which approach works best for you.
Beverly Hills, CaliforniaAges 18–80 - NCT06526650Recruiting
Cooking demos for Native Hawaiian adults with diabetes or heart risks
This trial tests if cooking demonstrations can help Native Hawaiian adults with conditions like type 2 diabetes, pre-diabetes, high blood pressure, or high cholesterol improve their health. You'd learn healthy cooking and be encouraged to do moderate activity like brisk walking.
Honolulu, HawaiiAges 18 years+ - NCT06526273Recruiting
PILI 'Āina Household Program
This study is for Native Hawaiian adults living in homestead communities who are overweight or have health conditions like diabetes, high blood pressure, or high cholesterol. It looks at a household-based program to help you and your family make healthier lifestyle changes together.
Honolulu, HawaiiAges 18 years+ - NCT06499857RecruitingPhase 3
Semaglutide for atrial fibrillation and weight loss
This study tests whether a weekly injection of semaglutide (the same drug in Wegovy and Ozempic) can help people with atrial fibrillation lose weight and improve their heart condition. It's for people with AF who also have obesity, and may or may not plan to have a heart procedure called catheter ablation.
Phoenix, ArizonaAges 18–75 - NCT06493084RecruitingPhase 1
Testing LAE102 in healthy and overweight adults
This study tests a new medicine called LAE102 in two groups: healthy volunteers and people who are overweight or obese. The goal is to see if it is safe and how the body processes it.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06491537Recruiting
Time-restricted eating for losing weight after having a baby
This study tests whether eating only during a specific daily window (time-restricted eating) helps new moms lose weight. It may be an option if you are 6 to 16 weeks postpartum and have a body mass index (BMI) of 25 or higher.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for obesity & overweight?
- Yes. Clin2 currently lists 494 recruiting obesity & overweight studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity & overweight trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity & overweight trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.