Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07738614RecruitingPhase 1
Testing an investigational weight loss medicine for adults with overweight or obesity
This study tests an experimental medicine (eloralintide) to see if it can help people with overweight or obesity lose weight without having diabetes. The medicine works by affecting hormones that help control appetite and body weight.
San Antonio, TexasAges 18–65 - NCT07685808RecruitingPhase 2
Testing a weight loss injection for people with overweight or obesity
This study tests an injectable medication called Olatorepatide to help people with overweight or obesity lose weight. It is only for people without diabetes who meet specific body mass index (BMI) requirements.
Walnut Creek, CaliforniaAges 18 years+ - NCT07774065Recruiting
Ventilation strategies in obese patients during laparoscopic surgery
This study tests different ways of using a breathing machine (ventilator) during laparoscopic surgery in people with obesity. The goal is to find a safer and more effective ventilation method for this group.
Galveston, TexasAges 18 years+ - NCT07774676Recruiting
Effects of obesity on muscle cell processes
This study looks at how obesity affects certain cell processes in muscle. It may help find new ways to treat or prevent muscle problems related to obesity.
BirminghamAges 18–45 - NCT03288207Recruiting
Phone-based coaching to help overweight Black women improve heart health
This study tests a mobile app (phone-based program) to help overweight or obese African American women improve weight and cardiovascular (heart) health. You’ll also use a wrist activity monitor, and you may be offered optional MRI scans for extra measurements.
Bethesda, MarylandAges 21–75 - NCT07213323Recruiting
Probiotics for Digestion During Weight-Loss Treatment
This study tests whether taking a probiotic (a type of 'good' bacteria) can improve digestion and gut health in people who are starting a GLP-1 RA medicine for weight loss. You would take the probiotic daily and answer questions about your digestive symptoms.
Pierre-BéniteAges 18–75 - NCT07693868RecruitingPhase 1
Study of a new medicine for obesity in healthy and overweight people
This study tests a new medicine (NNC6022-0004) in healthy volunteers and people with obesity to check its safety. If you qualify, you may help see if this drug is safe for future use.
GroningenAges 18–65 - NCT07218445RecruitingPhase 4
Tirzepatide for hot flashes in postmenopausal women with obesity
This study tests whether tirzepatide, a weekly injection, can reduce hot flashes and slow biological aging in postmenopausal women with obesity. It may help if you are experiencing bothersome hot flashes and are willing to follow a diet and exercise plan.
Jacksonville, FloridaAges 46–60 - NCT07567001RecruitingPhase 3
Testing NNC0487-0111 for Heart Failure and Obesity
This study tests whether a new medication called NNC0487-0111 can help people with heart failure who also have obesity. Researchers will compare it to a placebo (inactive pill) to see if it improves heart function and overall health.
Alexander City, AlabamaAges 18 years+ - NCT06700538RecruitingPhase 1/Phase 2
Study of an experimental drug for obesity with or without type 2 diabetes
This study tests an experimental medication called ARO-INHBE in adults with obesity, including those who also have type 2 diabetes. The goal is to see if it helps with weight loss and is safe.
CharlestownAges 18–65 - NCT06636058Recruiting
Digital treatment for weight and mood in adults 50+
This study tests a digital program that helps with weight loss and depression at the same time. It is designed for Black, Hispanic, and other adults over 50 who carry extra weight and feel down.
Chicago, IllinoisAges 50–74 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with overweight or obesity
This trial tests an investigational once-daily pill (ASC30) to see if it can help adults with overweight or obesity lose weight. You may be able to join if you have a high body mass index (BMI) and have tried to lose weight before.
Birmingham, AlabamaAges 18 years+ - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Birmingham, AlabamaAges 18 years+ - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Guntersville, AlabamaAges 18 years+ - NCT07351045RecruitingPhase 3
Study of enicepatide for weight loss in obesity or overweight
This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.
Anniston, AlabamaAges 18 years+ - NCT07670416RecruitingPhase 3
A study of enicepatide for people with obesity or overweight
This trial tests if enicepatide can help people with obesity or overweight lose weight, including those with or without type 2 diabetes. It aims to see if the drug is safe and effective.
Zhengzhou, HenanAges 18 years+ - NCT07757087RecruitingPhase 1
Study on energy use after weight loss
This study tests a new medicine to see how it affects the body's energy use after losing weight. It compares the medicine to a low-calorie diet or a placebo (a pill with no active ingredient) in adults with obesity.
Aarhus NAges 18 years+ - NCT06681246Recruiting
How gut bacteria affect weight regain after weight loss
This study looks at how the natural bacteria in your gut (the microbiome) might be linked to regaining weight after losing it. It tests whether a short course of antibiotics or a placebo (a sugar pill) affects this process. The goal is to find new ways to help people keep weight off long-term.
RehovotAges 18–65 - NCT07628127RecruitingPhase 1
Study of VRB-103 with or without ecnoglutide for weight loss
This early-stage trial tests two experimental medications—VRB-103 alone or combined with ecnoglutide—to help people with overweight or obesity lose weight. Both drugs are designed to help control appetite and may offer a new treatment option if you qualify.
MelbourneAges 18–60 - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Birmingham, AlabamaAges 18–79 - NCT07654361RecruitingPhase 3
A new pill for weight loss in obesity and overweight
This study tests an investigational pill called aleniglipron to see if it helps people with obesity or overweight who also have a weight-related health problem (like high blood pressure) lose weight safely. It is a Phase 3 trial, meaning it is in the final stages before seeking approval.
Birmingham, AlabamaAges 18–79 - NCT07291232RecruitingPhase 1
Study of an injected drug for adults with obesity
This study tests an injected medication called ABBV-295 for adults with obesity. The goal is to see how safe it is and how the body processes it. You may join if you have a BMI between 30 and 45 and are generally healthy, and you haven't been on other weight loss treatments recently.
Anaheim, CaliforniaAges 18–65 - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT06137365RecruitingPhase 2
Cannabis for Obesity Treatment Study
This study tests whether a cannabis product can help with weight loss in people with obesity. It is for those who have not used cannabis recently and are generally healthy.
Lexington, KentuckyAges 18–65
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.