Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,434 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06105957Recruiting
Digital weight loss program for rural adults
This study tests a digital weight loss program designed for adults living in rural areas. It uses a smartphone app, website, and video group sessions to help you lose weight through diet and physical activity.
Columbia, South CarolinaAges 18 years+ - NCT06105164Recruiting
Brain's Fullness Circuit Study
This study uses brain imaging and mild magnetic stimulation to explore how a brain circuit helps you feel full after eating. It may help us understand eating behaviors and weight regulation.
Belmont, MassachusettsAges 18–65 - NCT06129110Recruiting
Weight loss and muscle fat study for adults aged 18-70
This study looks at how losing weight affects the fat that sits inside your muscles (called intermuscular fat). It might help people with overweight to better understand how weight loss can improve muscle health.
Aurora, ColoradoAges 18–70 - NCT06118931Recruiting
Time-Restricted Eating for Blood Sugar Control
This study tests whether eating only during a specific daily window helps control blood sugar in people with or at risk for type 2 diabetes. You'll follow a set eating schedule and use a phone app to track your meals.
Toronto, OntarioAges 40 years+ - NCT06115265Recruiting
Ketogenic diet study for prediabetes and weight loss
This trial tests whether a ketogenic diet can help people with prediabetes or high blood sugar improve their health and lose weight. You eat very low-carb, high-fat foods to see if it lowers your blood sugar and reduces your risk of developing diabetes.
Albuquerque, New MexicoAges 18 years+ - NCT04352244Recruiting
Study of brown fat activity in healthy adults
This study measures how “brown fat” works in the body using planned medical procedures. It looks at healthy adults to understand brown fat activity and what affects it.
Boston, MassachusettsAges 18–75 - NCT05000996Recruiting
Gut microbiome study for people having metabolic surgery
This study looks at your gut bacteria (your “microbiome”) around the time of metabolic surgery. It may help researchers understand how surgery affects gut health and related conditions like diabetes, blood pressure, and cholesterol.
Nashville, TennesseeAges 21–65 - NCT06057597Recruiting
Comparing two types of gastric bypass surgery for weight loss
This trial compares a new version of gastric bypass (with a longer 150cm bypassed segment) to the standard Roux-en-Y gastric bypass to see which leads to better weight loss and health improvements. It is for people with severe obesity who are already scheduled for surgery and want to help find the best procedure.
ParisAges 18–65 - NCT06069622Recruiting
How a gene affects weight-loss treatment response
This study looks at how a weight-loss medication affects people with obesity who may have a specific gene difference (caveolin-1). It aims to understand why some people respond differently to GLP-1 treatments like semaglutide.
Boston, MassachusettsAges 18 years+ - NCT06063564Recruiting
Testing a digital tool to improve heart health in rural clinics
This study is testing a digital health app called PREVENT to help doctors and patients work together on heart-healthy habits like eating well and being active. It is designed for people in rural areas who want to lower their risk of heart disease.
St Louis, MissouriAges 18–64 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06043245Enrolling by invitation
Diabetes remission and weight loss surgery
This trial tests whether a specific type of weight loss surgery can help people with type 2 diabetes stop needing diabetes medication. It is for people with a very high body mass index (BMI over 45) who are currently on diabetes pills or insulin.
L'Hospitalet de Llobregat, BarcelonaAges 18–60 - NCT06044571Recruiting
Weight loss program for older adults via telehealth
This trial tests a weight loss program delivered through video calls to help adults aged 65-85 with obesity lose weight. It is designed for those with at least two other health conditions and who are ready to make changes.
Chapel Hill, North CarolinaAges 65–85 - NCT06051591Recruiting
Food FARMacia: Helping families with food worries
This study tests a program called Food FARMacia to help families with young children who sometimes worry about having enough food. The goal is to see if the program can help prevent childhood obesity by providing support and resources.
Stanford, CaliforniaAges 6 months+ - NCT06019182Recruiting
MEHMO syndrome: Understanding the condition over time
This study follows people with or at risk for MEHMO syndrome over time to better understand the condition and identify biological markers. It may include both affected individuals and their family members to see how the condition runs in families.
Bethesda, MarylandAges 1 week–100 years - NCT06018636Recruiting
Diet and nutrition in early childhood growth
This study looks at how diet and nutrition affect young children's growth and development. It may help you learn more about feeding your child well.
Swat, Khyber PakhtunkhwaAges 1 day–2 years - NCT06011499Recruiting
Online lifestyle program for prostate cancer survivors
This study tests an internet-based program to help prostate cancer survivors who are overweight and frail improve their health. You will be assigned to either a lifestyle coaching group or a usual care group, and both groups are followed for about 6 months.
Portland, OregonAges 18 years+ - NCT06015620Recruiting
Health changes after mini gastric bypass surgery
This study looks at how mini gastric bypass surgery helps with obesity-related health problems and changes in body composition. It aims to see if patients experience improvements in conditions like diabetes or high blood pressure.
Bhubaneswar, OdishaAges 18–65 - NCT06003686Recruiting
Spinal cord injury education study for adults
This study is looking at how well a special education program helps people with spinal cord injuries manage their health and daily life after leaving the hospital. It is for adults who recently finished their first rehabilitation stay and have a spinal cord injury from the C5 level or lower.
Washington D.C., District of ColumbiaAges 18–70 - NCT06009276Recruiting
Gut bacteria, muscle blood flow, and fitness study
This study looks at how the bacteria in your gut affect blood flow to your muscles and your overall fitness. You will provide samples and do some exercise tests to help researchers understand this link.
Charlottesville, VirginiaAges 18 years+ - NCT06020027Enrolling by invitation
Water Is K'é: Healthy Drink Choice Program for Navajo Families
This study helps Navajo families choose water and other healthy drinks instead of sugary ones. It works with families who have young children in early childhood programs.
Window Rock, ArizonaAges 2 years+ - NCT05774652Recruiting
Teen study following mothers from an earlier pregnancy project
This study follows teenagers whose mothers took part in an earlier lifestyle-in-pregnancy study (started in 2007–2010). It may help researchers understand how that earlier study relates to teen health and development.
OdenseAges 13–65 - NCT05985486Recruiting
Lifestyle change for brain health in Down syndrome
This study looks at how a healthy lifestyle program can improve brain health in adults with Down syndrome who are overweight or obese. You will attend a medical center three times over a year for tests, and you'll need a caregiver to support you.
Kansas City, KansasAges 18–64 - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70
Hear when a new Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,434 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.