Clinical trials
Obstructive Sleep Apnea (OSAS) clinical trials
Below are recruiting obstructive sleep apnea (osas) clinical trials, each written for real people, not researchers. We’re tracking 235 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05303987RecruitingPhase 2
Dexmedetomidine or propofol for sleep endoscopy in children
This Phase 2 study compares two medicines used to help children sleep during a procedure called drug-induced sleep endoscopy. It’s for children with obstructive sleep apnea who are being evaluated before adenotonsillectomy, to help surgeons understand the cause of the blockage and potentially improve treatment planning.
Ann Arbor, MichiganAges 3–11 - NCT05315752Recruiting
Body fat changes after CPAP-treated sleep apnea improves
This study looks at how bariatric (weight-loss) surgery may change body fat and body shape in people with severe obstructive sleep apnea who use CPAP. It aims to understand what may improve when sleep apnea is better controlled after surgery.
BrusselsAges 18–99 - NCT05350332Recruiting
Testing how lung air volume affects airway narrowing during sleep testing
This study looks at whether changing lung air volume affects how open or blocked your upper airway is during a drug-induced sleep test (DISE). It may help guide surgical choices for people with obstructive sleep apnea (OSA).
Atlanta, GeorgiaAges 18 years+ - NCT05382754Recruiting
Home sleep testing for children being checked for sleep apnea
This trial tests whether home sleep testing can help diagnose sleep apnea in children. It is for kids who are already being referred for an in-lab sleep study at CHOP.
Philadelphia, PennsylvaniaAges 5–12 - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Aurora, ColoradoAges 2–17 - NCT05527652Recruiting
Breathing tube device to help blocked upper airways in children
This study tests a self-supporting breathing tube placed through the nose during sleep to reduce upper airway blockage and improve breathing in children. It may help children who have sleep apnea symptoms, especially after tonsil/adenoid treatment or when tonsil removal isn’t possible.
Ann Arbor, MichiganAges 3–21 - NCT05539716Recruiting
Treating sleep apnea to study effects on metabolism
This study tests a sleep apnea treatment approach and looks at how it may affect your body’s metabolism. You may be eligible if you’re an adult with sleep apnea and meet health and medication rules, and possibly if you already use a PAP machine regularly.
Miami, FloridaAges 18–70 - NCT05558501RecruitingPhase 1/Phase 2
Intermittent low-oxygen therapy for sleep apnea and health risks
This early-stage study tests a treatment that briefly reduces oxygen during sleep to improve “plasticity,” with the goal of helping people with obstructive or mixed sleep apnea. It also looks at related conditions like high blood pressure and pre-diabetes or cholesterol problems, especially in people who haven’t tried CPAP yet.
Detroit, MichiganAges 30–60 - NCT05678088Recruiting
Exercises for sleep apnea when CPAP and other options don’t work
This trial tests whether doing exercises for the throat and mouth can reduce obstructive sleep apnea symptoms in people who cannot tolerate CPAP and aren’t using other device or surgery treatments. It may help if your apnea is mainly caused by blocked airflow rather than problems with breathing control.
Toronto, OntarioAges 18 years+ - NCT05735444Recruiting
CPAP registry for sleep apnea in people with high blood pressure
This study keeps a record of people with obstructive sleep apnea (OSA) who also have high blood pressure, to better understand how CPAP is used and what outcomes happen. It may help your care team by contributing your information to a large multi-center study in China.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05804084RecruitingPhase 2
Acetazolamide for sleep apnea: sleep and brain outcomes
This study tests acetazolamide (a medicine that changes breathing chemistry) to see how it affects sleep quality and neurocognitive (brain/memory/attention) outcomes in adults with untreated moderate to severe sleep apnea. You may be eligible if you have significant sleep apnea but do not have certain safety risks or need to start standard sleep apnea treatment right away.
La Jolla, CaliforniaAges 18 years+ - NCT05846490RecruitingPhase 4
Sleep apnea treatment to improve blood pressure in kidney disease
This study tests whether treating obstructive sleep apnea can help control blood pressure in people with chronic kidney disease. If your sleep apnea is not currently being treated, participation may help your care team see whether safer breathing at night improves blood pressure control.
São PauloAges 18 years+ - NCT05911646Recruiting
Tool to help decisions for mild sleep apnea in kids
This trial looks at OSA-18, a questionnaire that may help families and clinicians make better decisions about treatment for a child’s mild sleep apnea. It specifically focuses on children with enlarged tonsils and mild sleep study results.
Hartford, ConnecticutAges 3–12 - NCT05917119Recruiting
Bright light therapy for obstructive sleep apnea symptoms
This study tests whether a “bright light” treatment can reduce daytime sleepiness in people with obstructive sleep apnea who are already using CPAP or BiPAP. It may help people feel more awake during the day without changing their sleep apnea device use.
Pittsburgh, PennsylvaniaAges 40–65 - NCT05918120Recruiting
Check portable sleep testing for sleep apnea in people with high blood pressure
This study tests whether using portable electronic recorders can help find sleep apnea (OSA) in people who have hypertension and are at higher risk. It may help doctors screen sooner and better understand sleep apnea in people with blood-pressure problems.
Toronto, OntarioAges 18 years+ - NCT05939934Recruiting
Test a mouth device for sleep apnea after stopping CPAP
This study looks at whether a mandibular advancement device (a fitted mouthpiece) can control sleep apnea when you temporarily stop CPAP. It’s mainly for people who have been using CPAP for over a year but are now willing to try the mouth device.
AngersAges 18–75 - NCT05953610RecruitingPhase 2
Surgery study for sleep apnea when CPAP won’t work
This Phase 2 trial tests whether a specific type of palate surgery can treat moderate-to-severe obstructive sleep apnea in people who cannot tolerate CPAP (a breathing mask). It also checks patient traits (based on sleep testing) to see who is most likely to benefit from surgery.
Santa Monica, CaliforniaAges 21 years+ - NCT06043440RecruitingPhase 2
Oxygen therapy for sleep apnea in Down syndrome
This study tests whether oxygen therapy can help children with Down syndrome who have sleep apnea. It compares oxygen treatment to no treatment to see if it improves breathing during sleep and thinking skills.
Los Angeles, CaliforniaAges 5–18 - NCT06047496RecruitingEarly Phase 1
Time-restricted eating for sleep apnea
This study tests whether limiting your eating to a shorter daily window can improve health in people with untreated moderate to severe sleep apnea. You would eat all your meals within a set number of hours each day while tracking your progress on your smartphone.
La Jolla, CaliforniaAges 18–70 - NCT06089161Recruiting
Sleep Apnea Treatment and Alzheimer's Risk in Black Adults
This trial tests whether personalized sleep apnea treatment can help protect memory and thinking in Black older adults. If you have sleep apnea and are concerned about Alzheimer's, this study may help you and others like you.
Miami, FloridaAges 60–85 - NCT06103630Recruiting
Mouth exercises for sleep apnea with mouthguard therapy
This study tests whether specific mouth and throat exercises can help people with sleep apnea who already use a mandibular advancement device (a type of mouthguard). The goal is to see if adding exercises improves sleep and breathing.
TainanAges 20 years+ - NCT06115018Recruiting
Oral device for sleep apnea after palate surgery
This study tests whether a special oral device (OPR) can help people with sleep apnea after they have had palate surgery. It looks at how well it works and if the benefits last over time.
TainanAges 18–100 - NCT06117579Recruiting
Breathing Muscle Training for Sleep Apnea
This trial tests whether a simple breathing exercise (training the muscles you use to breathe in) can improve sleep apnea symptoms in people who already use CPAP. The goal is to see if adding this training helps you feel better or need less CPAP pressure.
OrléansAges 18 years+
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Common questions
- Are there clinical trials for obstructive sleep apnea (osas)?
- Yes. Clin2 currently lists 235 recruiting obstructive sleep apnea (osas) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive sleep apnea (osas) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive sleep apnea (osas) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.