Clinical trials
Obstructive Sleep Apnea (OSAS) clinical trials
Below are recruiting obstructive sleep apnea (osas) clinical trials, each written for real people, not researchers. We’re tracking 228 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07679282RecruitingPhase 4
Comparing sleep apnea treatments: CPAP, mouthpiece, or medication
This study compares three treatments for obstructive sleep apnea: a CPAP machine, a dental mouthpiece, and a combination of two medications (atomoxetine and oxybutynin). Researchers want to see which works best for people recently diagnosed with sleep apnea.
Tucson, ArizonaAges 18 years+ - NCT06677580Recruiting
OSA digital network for early diagnosis and monitoring
This trial tests a digital tool to help diagnose and monitor obstructive sleep apnea earlier. It may help people with sleep apnea get better care.
Milan, ItalyAges 18 years+ - NCT06681974RecruitingPhase 3
Throat therapy for sleep apnea without CPAP
This trial tests a type of mouth and throat therapy to see if it can help people with mild to moderate sleep apnea who can't or don't want to use a CPAP machine. It might be an option if you want a non-machine treatment for your sleep apnea.
SantanderAges 18–70 - NCT07635563RecruitingPhase 2
Sleep Apnea Treatment with Dronabinol and Acetazolamide
This study tests a combination medication (dronabinol and acetazolamide) to treat obstructive sleep apnea in people who cannot tolerate or use CPAP machines. The goal is to find the right dose that safely reduces breathing interruptions during sleep.
Chula Vista, CaliforniaAges 18–65 - NCT06711159Recruiting
Searching for a biomarker of sleepiness in severe sleep apnea
This study looks for a biological marker of severe daytime sleepiness in people with severe obstructive sleep apnea who haven't started breathing machine treatment yet. It may help doctors better understand and treat sleepiness in the future.
Koege, Regional ZealandAges 18 years+ - NCT07601724Recruiting
How fluid buildup affects sleep apnea in heart failure
This study looks at how excess fluid in the body affects sleep apnea (pauses in breathing during sleep) in people hospitalized with heart failure. Researchers will measure sleep apnea before and after treatment to reduce the fluid, which may help doctors better manage both conditions together.
JerusalemAges 18 years+ - NCT03929549Recruiting
Testing a tool to predict jaw surgery failure for sleep apnea
This trial studies a way to predict which people with obstructive sleep apnea (OSA) may not do well after maxillomandibular advancement surgery (jaw advancement). It could help doctors choose the right treatment and avoid ineffective surgery.
Ann Arbor, MichiganAges 30–65 - NCT07581938Recruiting
Early Dental Screening for Sleep Problems in Kids
This study uses a smartphone app and a wearable device to check for early signs of sleep-disordered breathing—a condition where breathing stops briefly during sleep—in children ages 8–13. The goal is to catch dental and jaw problems that might lead to sleep issues before they become serious.
Chapel Hill, North CarolinaAges 8–13 - NCT07577661RecruitingPhase 1/Phase 2
Electrical and medication combination therapy for sleep apnea
This trial tests whether combining electrical stimulation (via an Inspire device you already have or will get) with two medications can better treat obstructive sleep apnea. You'll help researchers understand if this combination works better than the device alone.
Boston, MassachusettsAges 18–79 - NCT07555119Recruiting
Home Sleep Testing: Night-to-Night Measurement Variability Study
This study measures how sleep breathing patterns vary from night to night using home sleep testing. It helps researchers understand if portable sleep tests give consistent and reliable results.
BernAges 18 years+ - NCT07530302Recruiting
Better ways to adjust CPAP therapy when it isn't working well
This trial tests whether a wearable device called Sunrise can help doctors adjust your CPAP machine better than standard sleep tests. If your current CPAP isn't stopping all your breathing pauses, this study may help find the right adjustments for you.
GrenobleAges 18–85 - NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT02630121RecruitingPhase 4
Nasal spray treatment to reduce mild sleep apnea congestion
This study tests whether using oxymetazoline with fluticasone nasal spray can improve mild obstructive sleep apnea by lowering nasal congestion. If your nose stays blocked most days despite current spray use, this may help your breathing during sleep.
Tampa, FloridaAges 18–65 - NCT07464262Recruiting
Telemonitoring with CPAP for severe sleep apnea patients
This trial tests whether telemonitoring (checking in remotely) helps people with severe sleep apnea adjust to CPAP therapy. If you live in São Paulo and recently started CPAP, this study may help you get extra support.
São Paulo, São PauloAges 18–75 - NCT07466888Recruiting
Adjusting electrical stimulation frequency for tongue muscle activity
This trial tests how changing the frequency of gentle electrical pulses to a tongue muscle affects its activity. It may help people with sleep apnea by strengthening the muscle that keeps the airway open during sleep.
Gyeonggi-do, Seongnam-siAges 19 years+ - NCT07447999Recruiting
Using AI to predict sleep apnea severity
This trial tests whether a special computer model can predict sleep apnea severity using a stethoscope and a fingertip oxygen sensor, instead of a full sleep test. It might help people get faster and easier sleep apnea diagnosis.
New Taipei CityAges 30–75 - NCT07447284Recruiting
Improving sleep for African American couples with OSA
This study tests whether a couple-based approach helps African American patients with moderate to severe sleep apnea stick with CPAP therapy better. It is designed for patients and their bed partners who want to improve sleep health together.
Cleveland, OhioAges 30 years+ - NCT07446634Recruiting
Jaw advancement surgery for sleep apnea
This study tests jaw advancement surgery for people with obstructive sleep apnea who haven't been helped by CPAP or mouthpieces. It looks at whether moving the jaw forward can improve breathing during sleep.
Falun, Dalarna CountyAges 18–70 - NCT07444372Recruiting
Starting CPAP therapy after atrial fibrillation ablation
This study tests whether starting CPAP therapy soon after a heart procedure called catheter ablation helps people with sleep apnea and atrial fibrillation (an irregular heartbeat) recover better and stay in normal rhythm. CPAP is a machine that helps keep your airway open while you sleep.
Beijing, Beijing MunicipalityAges 18–75 - NCT06286189RecruitingPhase 1/Phase 2
Testing trazodone for sleep apnea
This trial tests whether the medication trazodone can help people with moderate to severe obstructive sleep apnea (OSA). If you have OSA and are not taking certain medications or have other sleep disorders, you may be able to join.
Boston, MassachusettsAges 21–70 - NCT07434050RecruitingPhase 3
Study of XW003 for obesity with sleep apnea on CPAP therapy
This trial tests an investigational drug called XW003 to see if it helps people with obesity and obstructive sleep apnea who are already using a positive airway pressure (PAP) machine, like CPAP. It aims to improve weight loss and sleep apnea symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06668597Recruiting
Sleep apnea education and motivation program
This trial tests an educational program to help people with sleep apnea start using CPAP at home. The program is designed to motivate and guide you through the process of adapting to CPAP therapy.
Milan, MilanAges 18 years+ - NCT05115968Recruiting
Study tonsil cell changes in children with sleep apnea
This study uses a lab method called single-cell sequencing to look at tiny cells from tonsil tissue in children. It compares children with obstructive sleep apnea to children without it, to better understand what’s happening in the throat and how it may relate to needing tonsil removal.
Hong KongAges 6–11 - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+
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Common questions
- Are there clinical trials for obstructive sleep apnea (osas)?
- Yes. Clin2 currently lists 228 recruiting obstructive sleep apnea (osas) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obstructive sleep apnea (osas) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obstructive sleep apnea (osas) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.