Clinical trials
Occlusion clinical trials
Below are recruiting occlusion clinical trials, each written for real people, not researchers. We’re tracking 338 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07316933Recruiting
Exercise with light blood flow restriction before knee replacement
This trial tests if a specific type of exercise, done with a cuff that lightly restricts blood flow to your leg, can help you get stronger and recover better while you wait for knee replacement surgery. The blood flow restriction is carefully controlled and adjusted during exercise, which may make the workout more effective.
Valencia, ValenciaAges 50–85 - NCT06261021RecruitingPhase 2
Ruxolitinib cream for discoid lupus study
This trial tests a cream (ruxolitinib) on discoid lupus skin lesions. It aims to see if the cream can reduce DLE symptoms in adults.
Fredericton, New BrunswickAges 18 years+ - NCT07515937Recruiting
3D-Printed Bite Splint for Broken Jaws in Children
This study tests a custom 3D-printed bite splint to help heal straightforward jaw fractures in children aged 6–12. Instead of surgery, the splint guides the broken pieces back together while your child heals naturally.
Cairo, Cairo GovernorateAges 6–12 - NCT07571330Recruiting
Upper Tear Drain Plug for Dry Eye After Lower Plug
This trial tests whether adding a plug to your upper tear drain (in addition to an existing lower plug) helps severe dry eye. It may improve comfort by reducing tear loss.
Monterrey, Nuevo LeónAges 18 years+ - NCT07017062Recruiting
Study of ceramic veneers bonded with two self-adhesive dental cements
This trial compares two types of self-adhesive resin cements for bonding ceramic occlusal veneers. It aims to see which cement works better for restoring back teeth while keeping your natural tooth structure.
CairoAges 21 years+ - NCT07709182Recruiting
Guided breathing machine settings for weaning off ventilation
This trial compares two ways of adjusting the breathing machine to help patients come off it more smoothly. It uses a special measurement (airway occlusion pressure) to guide settings, which may help you breathe on your own faster.
Tanta, Al GharbiaAges 21 years+ - NCT07472231Recruiting
Game-based therapy for children with lazy eye
This trial tests if a fun, game-based training program can improve vision in children with lazy eye caused by a difference in glasses prescription between the two eyes. It is designed for children ages 4 to 7 who can participate in vision exercises.
Shanghai, Shanghai MunicipalityAges 4–7 - NCT06917378Recruiting
Study on blocked heart arteries over 3 months
This trial tests a procedure for people with a completely blocked heart artery that has been present for at least 3 months. It aims to see if opening the blockage can improve blood flow and heart function.
New Taipei CityAges 20–120 - NCT07082972RecruitingPhase 4
Study of splint therapy and Botox for jaw muscle pain
This trial compares two treatments—a dental splint and Botox injections into the jaw muscle (masseter)—to see which one better relaxes head and neck muscles in people with myofascial pain syndrome. It may help you if you have facial pain related to muscle tension.
Istanbul, VeznecilerAges 18–55 - NCT07300384Recruiting
Blood flow restriction training for knee pain relief before surgery
This study tests whether a special type of strength training (called blood flow restriction training) can reduce pain in people with severe knee arthritis who are waiting for knee replacement surgery. The training uses a cuff on the thigh to lightly restrict blood flow while doing exercises until failure.
Valencia, ValenciaAges 50–85 - NCT07369024RecruitingPhase 2
Study of low-dose ketamine for sickle cell pain crisis
This study tests whether a low-dose of ketamine (a pain medicine) can help children and young adults with sickle cell disease who are in a pain crisis. It aims to provide better pain relief while avoiding some side effects of standard painkillers.
Torrance, CaliforniaAges 5–20 - NCT07463664Recruiting
Drug-coated balloons for blocked heart arteries
This trial tests whether a drug-coated balloon, used without a permanent stent, can safely open completely blocked heart arteries that have been blocked for at least 3 months. It may offer an option that avoids leaving a metal stent behind.
Beijing, Beijing MunicipalityAges 18–80 - NCT07482228Recruiting
Long-term outcomes after retinal artery occlusion
This study looks at the long-term health results of people who have a retinal artery occlusion (a blockage in the blood vessels of the eye). It aims to understand what happens over time, which can help guide treatment and care.
Gwangju, GwangjuAges Any age - NCT07564297Enrolling by invitation
Long-term outcomes after fetal lung surgery for diaphragmatic hernia
This study follows babies born after a special fetal surgery (FETO) that places a temporary balloon in the baby's windpipe to help the lungs grow when they have a diaphragmatic hernia—a hole in the muscle that separates the chest from the belly. Researchers want to understand how these children do over time after this procedure.
Rochester, MinnesotaAges 18–50 - NCT06699849RecruitingPhase 2
CSL889 for sickle cell pain crisis
This trial tests a new medicine, CSL889, for people with sickle cell disease who are currently having a pain crisis (vaso-occlusive crisis). The goal is to see if it safely helps reduce the pain and speed recovery.
Oakland, CaliforniaAges 12 years+ - NCT07348640RecruitingPhase 3
Study of new MRI dye for blocked blood vessels
This trial tests a new MRI contrast dye (gadopiclenol) to see if it works as well as the standard dye for finding blocked or narrowed blood vessels. If you have symptoms of vascular disease, you may be able to join and help compare the two dyes.
Los Angeles, CaliforniaAges 18 years+ - NCT07749170Recruiting
Stroke treatment for blockages in smaller brain arteries
This study looks at how well a special catheter system works to remove blood clots from smaller arteries in the brain after a stroke. It aims to see if this treatment helps people recover better.
Knoxville, TennesseeAges 18 years+ - NCT07070583Recruiting
Effect of Leg Artery Blockage Treatment on Blood Pressure
This study looks at how treating blocked arteries in the lower belly and groin area affects blood pressure. If you have a long blockage in your main artery or the arteries to your legs that causes pain or trouble walking, this trial may help understand if treatment improves your blood pressure.
ArnhemAges 18 years+ - NCT06303414Recruiting
Opening blocked carotid artery for ongoing symptoms
This trial tests a procedure to open a blocked carotid artery in the neck to improve blood flow to the brain. It's for people who still have symptoms (like weakness or vision problems) despite medical treatment.
Beijing, Beijing MunicipalityAges 18–80 - NCT05551780Recruiting
Study for treating calcium blockages in leg artery disease
This trial tests a treatment approach for certain long-lasting, calcium-heavy blockages in the leg arteries that have no normal blood flow past the blockage. If you have these “total occlusions” and symptoms like walking pain or critical limb symptoms, this study may offer a new way to open the artery and restore blood flow.
Fort Lauderdale, FloridaAges 19 years+ - NCT04549896Recruiting
CT scan study for complex blocked heart artery procedures
This trial studies how a CT scan may help plan a procedure to open a long-standing blocked coronary artery (a chronic total occlusion). It is aimed at people with complex, difficult blockages and symptoms or heart test results showing parts of the heart may still be alive.
OllioulesAges 18–90 - NCT02352818Recruiting
Chronic heart artery blockage registry for treatment outcomes
This study is a registry that collects information about people who try to reopen a long-term blocked heart artery. It doesn’t test a new treatment—your doctors use standard care, and the registry helps learn what happens over time.
LeuvenAges 18 years+ - NCT03667196Recruiting
Test opening blocked heart arteries using two different procedures
This trial studies whether two ways of threading a device to open a long-term blocked coronary artery are both safe and effective. You may qualify if you have a chronic total blockage and heart-related symptoms, and you can follow the study follow-up plan.
AnyangAges 19 years+ - NCT03496792Recruiting
Study of blood pressure changes when standing up
This study checks how your blood pressure changes when you go from lying down to standing. It may help researchers understand why some people get “orthostatic hypertension” (higher blood pressure when standing) and how that reflex works.
Hershey, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for occlusion?
- Yes. Clin2 currently lists 338 recruiting occlusion studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a occlusion trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a occlusion trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.