Clinical trials
Chronic Total Occlusion (CTO) clinical trials
Below are recruiting chronic total occlusion (cto) clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06917378Recruiting
Study on blocked heart arteries over 3 months
This trial tests a procedure for people with a completely blocked heart artery that has been present for at least 3 months. It aims to see if opening the blockage can improve blood flow and heart function.
New Taipei CityAges 20–120 - NCT01889459Recruiting
Registry after stent procedure for blocked heart arteries
This study follows people who had a stent placed for a long-standing blockage in a heart artery (called a CTO). It’s mainly a “registry” to understand outcomes after these procedures and help improve care in the future.
KurashikiAges 20 years+ - NCT04944615Recruiting
IVUS-guided stent placement for blocked heart artery using longer guidance
This trial compares two ways to place a stent (a small mesh tube) for a completely blocked heart artery: using an IVUS camera inside the artery versus using a standard x-ray approach. It may help people get better heart outcomes by improving how accurately the stent is placed in long-term blockages.
BeijingAges 18 years+ - NCT06655922Recruiting
FAPI scan to assess chronic total heart artery blockages
This study is testing whether a special type of PET scan (called FAPI) can better see and understand fully blocked heart arteries (chronic total occlusions). If you're scheduled to have angioplasty to open such a blockage, this imaging might help guide the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07463664Recruiting
Drug-coated balloons for blocked heart arteries
This trial tests whether a drug-coated balloon, used without a permanent stent, can safely open completely blocked heart arteries that have been blocked for at least 3 months. It may offer an option that avoids leaving a metal stent behind.
Beijing, Beijing MunicipalityAges 18–80 - NCT07369765Recruiting
Balloon vs stent for blocked arteries
This trial compares two procedures to open completely blocked coronary arteries: a drug-coated balloon or a drug-eluting stent. It may help patients with a single, medium-length blockage in a large enough artery.
IstanbulAges Any age - NCT07330622Recruiting
Register of heart artery reopening procedures
This registry tracks people who get a procedure to open a completely blocked heart artery (called a chronic total occlusion). It helps doctors learn more about these procedures and how to improve them.
BialystokAges 18 years+ - NCT06957613Recruiting
A Registry for Chronic Total Heart Artery Blockages
This study is collecting information on people who have a complete blockage in a heart artery (a chronic total occlusion) and who are scheduled for a procedure to open it up. The goal is to learn more about the treatment and outcomes for these patients.
Bad Segeberg, Schleswig-HolsteinAges 18–100 - NCT07114393Recruiting
Better imaging to guide complex heart artery procedures
This study looks at whether using advanced imaging inside the heart arteries during complex procedures leads to better outcomes compared to current standard practice. If you have had a complex angioplasty (PCI) and your data is in a national heart registry, you may be included.
Eindhoven, North BrabantAges 18 years+ - NCT07020858Recruiting
FAPI imaging for heart attack risk in blocked arteries
This trial tests whether a special scan called FAPI-PET can predict heart problems in people with a chronic total occlusion (a completely blocked heart artery for at least 3 months). If you have this type of blockage and are planning to have a procedure to open it, this study may help guide your care.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06795763Enrolling by invitation
New imaging & catheter system for blocked heart arteries
This trial tests a new imaging and catheter system to treat chronic total blockages in heart arteries. If you still have chest pain or other symptoms despite medical therapy, this study may help open the blockage and improve blood flow.
Atlanta, GeorgiaAges 18 years+ - NCT06193954Recruiting
Vibrating guidewire for chronic heart artery blockages
This trial tests a special vibrating guidewire to help open heart arteries that have been completely blocked for a long time, when standard wires have failed. It may help you if you have a stubborn blockage requiring a gentle approach.
Atlanta, GeorgiaAges 18 years+ - NCT06275386Recruiting
Drug-coated balloon for chronic heart artery blockages
This trial tests whether a special balloon coated with medicine (drug-coated balloon) can safely open a completely blocked heart artery, instead of using a permanent stent. It may be an option for people who have chronic chest pain or shortness of breath due to a long-standing blockage.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06137521Recruiting
Heart artery blockage study
This study looks at people with a long-standing complete blockage in a heart artery. The goal is to understand risk factors and outcomes, which may help guide future treatments.
ShanghaiAges 18 years+ - NCT03563417Recruiting
CTO treatment vs medicines after heart scan
This trial studies whether opening a blocked coronary artery (a CTO) helps people more than staying on the best available heart medicines after an initial 3-month treatment period. It uses heart imaging to confirm there is reduced blood flow in the area supplied by the blockage.
Aarhus NAges 18 years+ - NCT03756870Recruiting
Stent procedure vs best medical care for blocked heart arteries
This trial studies whether opening a completely blocked heart artery (a CTO) with a procedure and stent helps reduce areas of low blood flow in the heart, compared with the best medicines alone. It uses heart scans to find people likely to benefit and then checks results again at 6 months.
AmsterdamAges 18 years+ - NCT03667196Recruiting
Test opening blocked heart arteries using two different procedures
This trial studies whether two ways of threading a device to open a long-term blocked coronary artery are both safe and effective. You may qualify if you have a chronic total blockage and heart-related symptoms, and you can follow the study follow-up plan.
AnyangAges 19 years+ - NCT05230446Recruiting
Testing full stent treatment for heart artery blockages
This study looks at how well doctors can treat multiple blocked heart arteries using a specific drug-eluting stent, aiming to fully open them. It may help patients whose blockage pattern fits the study, but it does not include certain high-risk or special cases.
Rotterdam, South HollandAges 18–85 - NCT06492733Recruiting
FastWire device for unblocking leg arteries (FREEFLOW trial)
This trial tests a new wire system to reopen completely blocked leg arteries without surgery. It is for people with severe leg pain or tissue damage caused by blocked arteries, and aims to restore blood flow and improve walking ability.
Wilmington, DelawareAges 18–85 - NCT02061436Recruiting
Chronic total occlusion procedure registry
This study collects data from patients who are having a procedure to open a completely blocked coronary artery. It may help improve future treatments for this condition.
Phoenix, ArizonaAges Any age
Hear when a new Chronic Total Occlusion (CTO) trial opens
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Common questions
- Are there clinical trials for chronic total occlusion (cto)?
- Yes. Clin2 currently lists 20 recruiting chronic total occlusion (cto) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic total occlusion (cto) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic total occlusion (cto) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.