Clinical trials
Open Surgery clinical trials
Below are recruiting open surgery clinical trials, each written for real people, not researchers. We’re tracking 104 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07805564Recruiting
Ultrasound score to predict kidney injury after heart surgery
This study tests whether an ultrasound score (VExUS) can predict kidney injury after open-heart surgery. It may help doctors adjust care to protect your kidneys.
Hanoi, HanoiAges 18 years+ - NCT07766031Recruiting
Comparing endoscopic and open surgery for herniated disc pain
This study compares two types of surgery for a herniated disc in the lower back: endoscopic (using a small camera) and open surgery. It aims to see which approach leads to less pain and less need for painkillers after the operation.
Saint-GrégoireAges 18 years+ - NCT07314996Recruiting
Laparoscopic vs. open surgery for colon cancer with belly fat
This trial compares laparoscopy (minimally invasive) and open surgery for treating colon cancer in people with extra belly fat around internal organs (visceral obesity). The goal is to see which approach gives better recovery and outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT06623578Recruiting
Robotic vs. open surgery for thyroid cancer that has spread
This study compares a robotic surgery method using small incisions under the armpit with standard open surgery for papillary thyroid cancer that has spread to lymph nodes on one side of the neck. It aims to see which approach is better for removing cancer and recovery.
Guangzhou, GuangdongAges 18–70 - NCT07257744Recruiting
Pain management after open heart surgery: comparing three methods
This trial compares three ways to manage pain after open heart surgery to see which best prevents long-term chronic pain. It may help you decide with your doctor which pain control option is right for you.
Trabzon, TrabzonAges 18–85 - NCT06707454Recruiting
Recovery after open heart surgery in older adults
This study looks at how older adults recover after open heart surgery, focusing on brain and nerve health. It may help researchers understand the effects of surgery on thinking and memory.
CairoAges 60 years+ - NCT06997419Recruiting
Dexamethasone for nausea after open surgery
This trial tests if a steroid called dexamethasone palmitate can prevent nausea and vomiting after open surgery. It is for people having planned spine, chest, or abdominal surgery under general anesthesia.
BeijingAges 18–65 - NCT04831580Recruiting
Robotic vs open hysterectomy for early cervix cancer
This trial compares robotic surgery to open (traditional) surgery for women with early-stage cervix cancer. The goal is to see which approach is safer and works better for cancer control and recovery.
Goodyear, ArizonaAges 18 years+ - NCT07040735Recruiting
Low-flow anesthesia study for open-heart surgery
This study tests a low-flow anesthesia method during open-heart surgery to see if it works well and safely. It may help patients by using less medication.
AnkaraAges 18 years+ - NCT05767164Recruiting
Study links surgery outcomes to test results in cervical spine disease
This study looks at how measurements from symptoms, exams, and MRI results relate to recovery after a specific type of neck surgery (“single open-door” surgery). It may help doctors better predict who is more likely to do well after this operation.
Xi'an, Shannxi ProvinceAges 18–86 - NCT07853586Recruiting
Numbing blocks for pain relief after children's belly surgery
This study compares two types of numbing injections (nerve blocks) given before surgery to see which one controls pain better in children after lower belly surgery. If your child qualifies, they may receive one of these blocks to help them be more comfortable after the operation.
AlexandriaAges 2–7 - NCT07200271Recruiting
Surgery for chronic ankle instability: Broström vs allograft
This trial compares two surgical techniques to fix chronic ankle instability. It is for people with ongoing ankle weakness, multiple sprains, or loose ligaments who have not had ankle surgery before.
Valdemoro, MadridAges 18 years+ - NCT06409156Recruiting
Comparing two nerve blocks for upper abdominal surgery pain
This trial tests two different types of nerve blocks to see which one provides better pain relief after upper belly surgery. If you are having open surgery on your stomach, liver, pancreas, or spleen, this study may help reduce your need for strong opioids.
Cleveland, OhioAges 18 years+ - NCT07831252Recruiting
Blood pressure and oxygen levels during heart surgery
This study looks at how blood pressure changes during the start of open heart surgery and whether it affects oxygen levels in body tissues. It may help doctors better manage blood pressure during surgery to keep patients safe.
Istanbul, SultangaziAges 18–90 - NCT07037485Recruiting
Predicting kidney injury after open heart surgery
This trial tests if kidney ultrasound and urine oxygen levels can predict acute kidney injury after open heart surgery. It aims to help doctors catch kidney problems early.
Tanta, El-GharbiaAges 21 years+ - NCT06638593Recruiting
Comparing open vs. robotic surgery for pelvic masses up to 8cm
This study compares two types of minimally invasive surgery—traditional laparoscopic (keyhole) versus robotic-assisted—for removing complex ovarian cysts or masses up to 8cm that haven't spread. The goal is to see which approach might offer better recovery and outcomes for women with these growths.
GuildfordAges 18–100 - NCT07872150Recruiting
Minimally invasive vs. open surgery for varicose vein treatment
This study compares two surgical approaches for treating advanced varicose veins, one using a small camera and the other using traditional open surgery. The goal is to see which method provides better results with fewer complications.
Lahore, Punjab ProvinceAges 18–70 - NCT06888154Recruiting
Hot compress use after open abdominal surgery
This trial tests if applying a warm compress to the abdomen after open belly surgery can help recovery. It aims to see if this simple, drug-free method reduces pain or improves bowel function.
Merkez, KırşehirAges 18–65 - NCT06246136Recruiting
Laser treatment for glaucoma during cataract surgery
This study tests a new laser treatment (ELIOS) for people with open-angle glaucoma who also need cataract surgery. It aims to see if the laser is safe and effective at lowering eye pressure while removing the cataract.
LeuvenAges 40 years+ - NCT03881345Recruiting
Registry for blood clots in legs or lungs
This registry collects information from people who have a blood clot in a leg or a clot in the lung. It helps researchers understand how these conditions are treated in real life.
Moscow, MoscowAges 18 years+ - NCT06534372Recruiting
Factors affecting chronic pain after open-heart surgery
This study looks at factors that may lead to long-term pain after open-heart surgery. It follows patients who have coronary bypass or valve surgery to understand what might cause ongoing pain.
Ankara, AnkaraAges 18–80 - NCT06848946RecruitingPhase 4
Eye implant with cataract surgery vs. cataract surgery alone
This trial tests if a tiny implant called iDose® TR, placed during cataract surgery, can better control eye pressure in people with glaucoma or high eye pressure compared to cataract surgery alone.
Kenosha, WisconsinAges 45 years+ - NCT03785743Recruiting
Compare keyhole vs open surgery for pancreatic cancer
This trial compares two ways of doing surgery for pancreatic cancer: keyhole (small cuts) versus open surgery (one larger cut). It’s meant to see which approach works better for people who are well enough for either option.
Wuhan, HubeiAges 18–75 - NCT07653152Recruiting
Endoscopic vs open surgery for male breast reduction
This study compares two surgical approaches for removing male breast gland tissue in men with gynecomastia. One method uses small cuts and a camera (endoscopic), the other uses a standard cut (open surgery) – both aim to preserve the nipple and areola.
AntalyaAges 18–60
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Common questions
- Are there clinical trials for open surgery?
- Yes. Clin2 currently lists 104 recruiting open surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.