Clinical trials
Open Surgery clinical trials
Below are recruiting open surgery clinical trials, each written for real people, not researchers. We’re tracking 105 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06551714Recruiting
Movement techniques after first open heart surgery
This study tests special movement and breathing techniques to help people recover faster after their first open heart surgery. It focuses on improving health in the early days after surgery.
AnkaraAges 18–75 - NCT07314996Recruiting
Laparoscopic vs. open surgery for colon cancer with belly fat
This trial compares laparoscopy (minimally invasive) and open surgery for treating colon cancer in people with extra belly fat around internal organs (visceral obesity). The goal is to see which approach gives better recovery and outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT06623578Recruiting
Robotic vs. open surgery for thyroid cancer that has spread
This study compares a robotic surgery method using small incisions under the armpit with standard open surgery for papillary thyroid cancer that has spread to lymph nodes on one side of the neck. It aims to see which approach is better for removing cancer and recovery.
Guangzhou, GuangdongAges 18–70 - NCT07257744Recruiting
Pain management after open heart surgery: comparing three methods
This trial compares three ways to manage pain after open heart surgery to see which best prevents long-term chronic pain. It may help you decide with your doctor which pain control option is right for you.
Trabzon, TrabzonAges 18–85 - NCT06707454Recruiting
Recovery after open heart surgery in older adults
This study looks at how older adults recover after open heart surgery, focusing on brain and nerve health. It may help researchers understand the effects of surgery on thinking and memory.
CairoAges 60 years+ - NCT06997419Recruiting
Dexamethasone for nausea after open surgery
This trial tests if a steroid called dexamethasone palmitate can prevent nausea and vomiting after open surgery. It is for people having planned spine, chest, or abdominal surgery under general anesthesia.
BeijingAges 18–65 - NCT04831580Recruiting
Robotic vs open hysterectomy for early cervix cancer
This trial compares robotic surgery to open (traditional) surgery for women with early-stage cervix cancer. The goal is to see which approach is safer and works better for cancer control and recovery.
Goodyear, ArizonaAges 18 years+ - NCT05767164Recruiting
Study links surgery outcomes to test results in cervical spine disease
This study looks at how measurements from symptoms, exams, and MRI results relate to recovery after a specific type of neck surgery (“single open-door” surgery). It may help doctors better predict who is more likely to do well after this operation.
Xi'an, Shannxi ProvinceAges 18–86 - NCT07040735Recruiting
Low-flow anesthesia study for open-heart surgery
This study tests a low-flow anesthesia method during open-heart surgery to see if it works well and safely. It may help patients by using less medication.
AnkaraAges 18 years+ - NCT06592755Recruiting
New scar-free thyroid surgery vs. standard surgery for thyroid cancer
This trial compares a new, scar-free surgery (done through a small cut near the collarbone) to the standard open surgery for people with a common type of thyroid cancer. It may be a good option if your cancer is small and hasn't spread.
Guangzhou, GuangdongAges 18–70 - NCT07200271Recruiting
Surgery for chronic ankle instability: Broström vs allograft
This trial compares two surgical techniques to fix chronic ankle instability. It is for people with ongoing ankle weakness, multiple sprains, or loose ligaments who have not had ankle surgery before.
Valdemoro, MadridAges 18 years+ - NCT06409156Recruiting
Comparing two nerve blocks for upper abdominal surgery pain
This trial tests two different types of nerve blocks to see which one provides better pain relief after upper belly surgery. If you are having open surgery on your stomach, liver, pancreas, or spleen, this study may help reduce your need for strong opioids.
Cleveland, OhioAges 18 years+ - NCT07037485Recruiting
Predicting kidney injury after open heart surgery
This trial tests if kidney ultrasound and urine oxygen levels can predict acute kidney injury after open heart surgery. It aims to help doctors catch kidney problems early.
Tanta, El-GharbiaAges 21 years+ - NCT06638593Recruiting
Comparing open vs. robotic surgery for pelvic masses up to 8cm
This study compares two types of minimally invasive surgery—traditional laparoscopic (keyhole) versus robotic-assisted—for removing complex ovarian cysts or masses up to 8cm that haven't spread. The goal is to see which approach might offer better recovery and outcomes for women with these growths.
GuildfordAges 18–100 - NCT06888154Recruiting
Hot compress use after open abdominal surgery
This trial tests if applying a warm compress to the abdomen after open belly surgery can help recovery. It aims to see if this simple, drug-free method reduces pain or improves bowel function.
Merkez, KırşehirAges 18–65 - NCT06246136Recruiting
Laser treatment for glaucoma during cataract surgery
This study tests a new laser treatment (ELIOS) for people with open-angle glaucoma who also need cataract surgery. It aims to see if the laser is safe and effective at lowering eye pressure while removing the cataract.
LeuvenAges 40 years+ - NCT03881345Recruiting
Registry for blood clots in legs or lungs
This registry collects information from people who have a blood clot in a leg or a clot in the lung. It helps researchers understand how these conditions are treated in real life.
Moscow, MoscowAges 18 years+ - NCT06534372Recruiting
Factors affecting chronic pain after open-heart surgery
This study looks at factors that may lead to long-term pain after open-heart surgery. It follows patients who have coronary bypass or valve surgery to understand what might cause ongoing pain.
Ankara, AnkaraAges 18–80 - NCT06848946RecruitingPhase 4
Eye implant with cataract surgery vs. cataract surgery alone
This trial tests if a tiny implant called iDose® TR, placed during cataract surgery, can better control eye pressure in people with glaucoma or high eye pressure compared to cataract surgery alone.
Kenosha, WisconsinAges 45 years+ - NCT06616129Recruiting
Geriatric risk assessment for older heart surgery patients
This study tests whether a special geriatric risk assessment and shared decision-making conversation helps older patients (70+) and their doctors choose the best treatment for heart surgery. It aims to improve quality of life by tailoring decisions to each person's health risks.
Groningen, Provincie GroningenAges 70 years+ - NCT03785743Recruiting
Compare keyhole vs open surgery for pancreatic cancer
This trial compares two ways of doing surgery for pancreatic cancer: keyhole (small cuts) versus open surgery (one larger cut). It’s meant to see which approach works better for people who are well enough for either option.
Wuhan, HubeiAges 18–75 - NCT06483516Recruiting
Quality of life after AAA surgery: EVAR vs open repair
This trial compares two ways to fix a large abdominal aortic aneurysm (AAA) and looks at how your quality of life changes after surgery. One method uses a small tube (stent) inserted through a blood vessel, and the other is traditional open surgery. It may help you understand the best option for you.
ToulouseAges 18 years+ - NCT07653152Recruiting
Endoscopic vs open surgery for male breast reduction
This study compares two surgical approaches for removing male breast gland tissue in men with gynecomastia. One method uses small cuts and a camera (endoscopic), the other uses a standard cut (open surgery) – both aim to preserve the nipple and areola.
AntalyaAges 18–60 - NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+
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Common questions
- Are there clinical trials for open surgery?
- Yes. Clin2 currently lists 105 recruiting open surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.