Clinical trials
Open Surgery clinical trials
Below are recruiting open surgery clinical trials, each written for real people, not researchers. We’re tracking 105 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05564091Recruiting
Add a minimally invasive canaloplasty step to cataract surgery
This trial compares standard cataract surgery alone versus cataract surgery plus a procedure to improve fluid drainage in the eye. It is intended for people with mild to moderate open-angle glaucoma, to see if adding this step helps control eye pressure and preserve vision.
Sugar Land, TexasAges 55 years+ - NCT07580443Recruiting
Quality of Life After Open Surgery for Complex Aortic Aneurysms
This study follows patients who have had open surgery to repair complex abdominal aortic aneurysms—bulges in the main blood vessel in the belly. Researchers will ask you about your quality of life after surgery to understand how well people recover and feel.
LucerneAges 18 years+ - NCT03797690Recruiting
Needle procedure for Dupuytren’s hand contracture
This trial looks at whether a minimally invasive needle procedure can improve hand stiffness caused by Dupuytren’s disease. It may help reduce finger bending that affects how you use your hand.
ParisAges 18 years+ - NCT07134361Recruiting
Ultrasound study for carpal tunnel syndrome
This study uses hand ultrasound to evaluate carpal tunnel syndrome before and after surgery. It may help doctors understand how the wrist changes after treatment.
São Paulo, São PauloAges 18 years+ - NCT07048522Recruiting
Nimodipine before bowel cancer surgery
This trial tests if giving nimodipine before and after surgery for bowel cancer can help improve recovery and reduce pain. It may be a good fit if you meet the age and health requirements.
Pátrai, AchaeaAges 18–75 - NCT06725030Recruiting
Robotic surgery for lymphedema (Symani System)
This trial uses a robotic arm called Symani to help surgeons perform more precise microsurgery (working on tiny blood vessels and lymph channels). It is for adults with moderate lymphedema in one arm or leg who have already tried standard lymphedema therapy and still have swelling.
Beverly Hills, CaliforniaAges 22 years+ - NCT06720922Recruiting
Laser surgery for drug-resistant epilepsy
This trial tests a new, less invasive surgery called MRI-guided laser ablation (MRgLITT) for people with drug-resistant mesial temporal lobe epilepsy. It aims to stop or reduce seizures by using a laser to destroy the tiny area of the brain causing them.
Beijing, Beijing MunicipalityAges Any age - NCT03849443RecruitingEarly Phase 1
Testing tranexamic acid to reduce bleeding after spine fusion
This trial studies whether a single dose or multiple doses of tranexamic acid (TXA) can reduce the chance you need a blood transfusion after spine fusion surgery. It also compares two different ways TXA may be given (by mouth and through a vein) to see which approach works best and is safe.
Chicago, IllinoisAges 18 years+ - NCT06738654Recruiting
Robotic breast-conserving surgery through the armpit for early-stage breast cancer
This trial tests a new robotic technique for removing early-stage breast cancer through the armpit, leaving no scar on the chest. It may be an option for women who want to keep their breast shape and avoid visible scarring.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT07510451Recruiting
Predicting low blood pressure during major aortic surgery
This trial tests a new monitoring tool that predicts drops in blood pressure before they happen during major aortic surgery. It may help doctors keep your blood pressure more stable during the procedure.
Poznan, PoznańAges 18 years+ - NCT07816692Recruiting
iDose implant for open-angle glaucoma
This study tests a tiny implant, called iDose, that is placed in the eye during a short office procedure to help lower eye pressure in people with open-angle glaucoma or high pressure in the eye (ocular hypertension). It may offer a way to manage pressure without daily eye drops.
Austin, TexasAges 18 years+ - NCT07665593Recruiting
AI breathing training after open heart surgery
This trial tests if an AI-assisted breathing exercise device can reduce pain, fatigue, and improve breathing in patients recovering from open heart surgery.
Kocaeli, İzmitAges 18 years+ - NCT07591987Recruiting
Breathing Techniques to Reduce Shortness of Breath After Heart Surgery
This study tests whether special breathing exercises can help reduce shortness of breath and improve heart and lung function in patients recovering from open-heart surgery. You would learn and practice these breathing techniques before and after your surgery.
Baghdad, Baghdad GovernorateAges 18–75 - NCT07477977Recruiting
Finding the right dose of protamine to reverse heparin after heart bypass
This study is testing different doses of a medication called protamine, which is given after heart surgery to reverse the effects of heparin (a blood thinner). The goal is to find the safest and most effective dose for patients who have had a heart-lung bypass machine during surgery.
SohagAges 18 years+ - NCT07413965Recruiting
Transcatheter vs surgical valve replacement for severe bicuspid aortic stenosis
This trial compares two ways to replace a narrowed heart valve in people with a bicuspid aortic valve. If you're 50 or older and need a new valve, this study can help figure out which approach works best.
Los Angeles, CaliforniaAges 50 years+ - NCT07408921Recruiting
Ice or Warm Pack for Drain Removal Comfort
This study tests whether putting an ice pack or a warm gel pad on your skin before pulling out a surgical drain can lower anxiety and pain, and make you more comfortable. It is designed for people who had open urological surgery and have one drain that needs to be removed.
Mersin, TurkeyAges 18 years+ - NCT07385430RecruitingPhase 1
Study of LGW16-03 to highlight nerves during surgery
This trial tests a dye called LGW16-03 that may help surgeons see nerves more clearly during open surgery. It is for people who are already scheduled for surgery where a major nerve will be exposed.
Lebanon, New HampshireAges 18 years+ - NCT07351253Recruiting
Nerve block comparison for open appendix surgery
This study tests two types of nerve blocks (Erector Spinae Plane Block and Lateral Transversus Abdominis Plane Block) to see which provides better pain relief after open appendectomy. This could help reduce pain and the need for stronger painkillers after surgery.
Cairo, Cairo GovernorateAges 21 years+ - NCT06935708RecruitingPhase 4
Comparing morphine to epidural pain relief for colon surgery
This study compares two pain relief methods—morphine given through a spinal needle versus pain medicine delivered through a tiny tube in the back—after colorectal cancer surgery. It aims to see which approach works better for controlling pain.
SplitAges 18–80 - NCT07120529Recruiting
Comparing two types of hysterectomy for early cervical cancer
This study looks at two ways to remove the uterus and cervix for early-stage cervical cancer: minimally invasive surgery (like laparoscopic or robotic) versus open surgery (traditional large incision). It checks whether the less invasive approach works just as well in terms of survival and keeping the cancer from coming back.
BialystokAges 18–85 - NCT06996561RecruitingPhase 2/Phase 3
How your genes affect pain relief after surgery
This study looks at how your genes might affect pain relief from a medication called nalbuphine after abdominal or pelvic surgery. It aims to personalize pain management based on your genetic makeup.
Karachi, SindhAges 18–70 - NCT06828432Enrolling by invitation
Device study for heart surgery patients in the heart intensive care unit
This trial tests a new device that measures heart function closely after heart surgery. It may help doctors give better care if you are in the heart intensive care unit after your operation.
Pittsburgh, PennsylvaniaAges 18–105 - NCT06562634Enrolling by invitation
Ultrasound-guided nerve block for knee surgery pain relief
This study tests a nerve block (erector spinae plane block) to see if it reduces pain after open knee surgery. It aims to find a better way to manage pain with fewer side effects.
CairoAges 18–65 - NCT06322810Recruiting
Pain relief methods for open heart surgery: ESP vs PIFB
This study compares two ways to manage pain after open-heart surgery. It looks at using an injection near the spine (ESP block) versus a needle placed through the chest wall (PIFB) to help reduce pain and the need for strong pain medicines.
Taichung, TaiwanAges 18 years+
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Common questions
- Are there clinical trials for open surgery?
- Yes. Clin2 currently lists 105 recruiting open surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a open surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a open surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.