Clinical trials
Orthopedic Surgery clinical trials
Below are recruiting orthopedic surgery clinical trials, each written for real people, not researchers. We’re tracking 47 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06818552Recruiting
Vascular surgeon's role in orthopedic tumor surgery
This trial is looking at how a vascular surgeon can help during surgery for tumors that involve blood vessels. It may help people with bone or soft tissue tumors that are close to or wrapped around major blood vessels.
Bologna, ItaliaAges 18 years+ - NCT06819436RecruitingPhase 4
Dexamethasone for spinal anesthesia side effects
This trial tests if a steroid called dexamethasone can prevent low blood pressure after spinal anesthesia for orthopedic surgery. If you are having hip, knee, or other bone surgery with spinal anesthesia and are otherwise healthy, this study may help reduce side effects.
Karachi, SindhAges 65–85 - NCT06320041RecruitingPhase 4
Oliceridine for pain after orthopedic surgery
This trial tests a new painkiller called oliceridine for moderate to severe pain after orthopedic surgery. It may help you recover more comfortably with fewer side effects.
Yiwu, ZhejiangAges 18–100 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT07356323Recruiting
Study on antibacterial drape for hip or knee replacement
This trial tests if a special antibacterial drape reduces contamination during hip or knee replacement surgery. The drape is placed over the skin to help prevent infection.
Fishers, IndianaAges 22 years+ - NCT07353996RecruitingPhase 4
Finding the right dose of a new IV painkiller after bone surgery
This trial tests a single dose of a new pain medicine called tegileridine fumarate given through a vein right after orthopedic surgery (like spine, hip, or knee surgery). The goal is to find the best dose that works well for pain without causing side effects.
Hanzhong, ZhejiangAges 18–75 - NCT06664203Recruiting
Nerve block for arm surgery pain relief
This trial tests a special type of nerve block (called variable volume truncal block) for pain relief during arm, elbow, forearm, hand, or wrist surgery. It may help reduce pain and the need for strong pain medicines.
IstanbulAges 18–65 - NCT07342647Recruiting
Safer antibiotics for people with beta-lactam allergies in joint replacement surgery
This trial tests a better way to choose antibiotics during joint replacement surgery for patients who are allergic to beta-lactams (a common class of antibiotics). The goal is to prevent infections while avoiding allergic reactions.
StrasbourgAges 18 years+ - NCT07290504Recruiting
Tourniquet Release Methods for People with High Blood Pressure
This study tests two ways of releasing a tourniquet (a pressure cuff) after arm surgery to see which keeps blood pressure more stable in people with controlled high blood pressure. If you are having arm or hand surgery with a tourniquet, you may be able to join.
CairoAges 18–65 - NCT07078201RecruitingPhase 4
Comparing two pain meds in spinal anesthesia for leg surgery
This study compares two medicines (dexmedetomidine and fentanyl) added to a spinal numbing shot for people having planned leg or knee surgery. The goal is to see which one works better to keep your blood pressure stable, and to make the numbing last while keeping you comfortable.
Port SaidAges 20–60 - NCT07047469Recruiting
Ultrasound-guided spinal anesthesia in orthopedic surgery
This study compares two ways of giving spinal anesthesia (midline vs. paramedian) using ultrasound guidance in adults having orthopedic surgery. The goal is to see which approach is safer and more effective.
SohagAges 18–50 - NCT06854913Enrolling by invitation
Shoulder Surgery and Sleep in Workers
This study looks at how shoulder surgery affects the sleep of people who do physical work. If you are having shoulder surgery, researchers want to see if your sleep changes after the operation.
Rome, ItalyAges 18 years+ - NCT06604364Recruiting
Virtual reality to reduce anxiety before children's arm or leg surgery
This study tests whether watching a virtual reality video can help calm children aged 7 to 12 before minor orthopedic surgery. If your child is having a short procedure (less than an hour) with a numbing shot instead of full sleep medicine, this might be a good fit.
BolognaAges 7–12 - NCT06107959Recruiting
Metabolism changes after bone or joint surgery
This study measures how your metabolism (how fast your body burns energy) changes after orthopedic surgery (surgery on bones or joints). It may help doctors understand how to better support recovery.
Kansas City, KansasAges 15 years+ - NCT05899153Recruiting
Gait training with feedback for children with cerebral palsy
This trial tests whether walking practice with real-time feedback (“biofeedback”) can improve how people with cerebral palsy move their legs. It’s designed to help with safer, more efficient walking during treadmill training.
Saint Paul, MinnesotaAges 7–18 - NCT05168943Recruiting
Comparing nylon and polyurethane epidural tubes for major surgery
This trial compares two types of epidural catheters (nylon vs polyurethane) in people having major orthopedic surgery. It may help find which catheter type is safer and works better for pain control during and after surgery.
Damanhūr, El-BeheiraAges 21–60 - NCT05112302Enrolling by invitation
Virtual reality during orthopedic anesthesia
This study tests whether using virtual reality during hip or knee surgery (while you’re receiving a nerve block for anesthesia) helps make the experience more comfortable. You’d try the VR during your procedure, and the team will compare outcomes with usual care.
Jackson, FloridaAges 18 years+ - NCT04109638Recruiting
PEMF therapy to reduce pain after shoulder or knee surgery
This trial studies whether PEMF, a type of non-surgical device that uses pulsed electromagnetic fields, can reduce pain after shoulder or knee surgery. If you join, you’ll also be expected to do post-surgery physical therapy exercises and report your pain and function.
Redwood City, CaliforniaAges 18 years+ - NCT06381791RecruitingPhase 1/Phase 2
CBD for pain after shoulder surgery
This study tests if CBD (a cannabis extract) can help manage pain after rotator cuff repair surgery. It aims to find a better way to control pain and reduce the need for stronger painkillers.
Houston, TexasAges 18 years+ - NCT06179004RecruitingPhase 3
Numbing medicine comparison for wrist surgery pain
This study compares two types of numbing medicine (bupivacaine and liposomal bupivacaine) given near the collarbone before wrist surgery to see which provides better pain relief afterward.
Chapel Hill, North CarolinaAges 18 years+ - NCT05534724Recruiting
Compare early vs partial weight bearing after bunion surgery
This study compares whether it’s safer to put weight on your foot early versus only partly after bunion surgery. It may help your care team choose the best recovery plan for healing and comfort.
LuganoAges 18–85 - NCT06877078Recruiting
Podcast for constipation before surgery
This study tests if listening to a podcast about preventing constipation before surgery can help people who are having back, shoulder, knee, or hip surgery. If you are scheduled for one of these surgeries, you may be able to take part.
SilkeborgAges 18 years+ - NCT05381818Recruiting
Breathing muscle training before joint surgery
This trial tests whether strengthening breathing muscles before total joint surgery can lower the chance of lung complications after the operation. It may help people who already have breathing problems or a history of smoking.
Jacksonville, FloridaAges 18–100
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Common questions
- Are there clinical trials for orthopedic surgery?
- Yes. Clin2 currently lists 47 recruiting orthopedic surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a orthopedic surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a orthopedic surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.