Clinical trials
Osteoarthritis clinical trials
Below are recruiting osteoarthritis clinical trials, each written for real people, not researchers. We’re tracking 592 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT07637682Recruiting
Percutaneous Neurostimulation for Knee Osteoarthritis Pain
This trial tests a minimally invasive nerve-stimulation treatment for moderate to severe knee osteoarthritis pain in adults who have not found relief with standard treatments. The procedure uses small needles to deliver electrical stimulation near nerves to reduce pain.
TantaAges 18 years+ - NCT05423587Recruiting
Knee artery procedure for long-lasting knee arthritis pain
This study looks at whether blocking small blood vessels in the knee (genicular artery embolisation) can reduce pain from knee osteoarthritis when other non-surgical treatments haven't helped. It also checks safety and whether people can tolerate the imaging tests needed for the procedure.
ReadingAges 45 years+ - NCT05980793Recruiting
Nerve Treatment for Finger Joint Osteoarthritis
This study tests if a procedure that quiets the nerves around a painful finger joint (PIP joint denervation) can reduce pain and improve hand function for people with osteoarthritis. It offers a possible alternative before considering more invasive surgery.
StockholmAges 18 years+ - NCT07603973Recruiting
Smartphone App to Help Manage Knee Osteoarthritis
This study tests whether a smartphone app that provides information and self-management tools helps people with knee osteoarthritis feel better and manage their condition. You would use the app at home to learn exercises, track symptoms, and get support.
Oslo, OsloAges 50 years+ - NCT07598474Recruiting
Pregabalin and Movement Therapy for Knee Osteoarthritis Pain
This trial tests whether a nerve pain medication called pregabalin, applied through ultrasound waves to your knee, combined with gentle movement exercises, can reduce pain in advanced knee osteoarthritis. You'll attend 16 treatment sessions over 4 weeks to see if this combination helps.
Faisalābad, Punjab ProvinceAges 40–60 - NCT06716281RecruitingPhase 3
Stem cell injection for knee osteoarthritis
This study tests a new stem cell treatment for knee osteoarthritis. It aims to see if injecting these cells into the knee can reduce pain and improve function compared to other treatments.
ShanghaiAges 40–80 - NCT05962463Recruiting
Compare two pain injections for advanced knee arthritis
This trial compares pulsed radiofrequency therapy versus a targeted nerve pain block to help reduce knee pain from advanced osteoarthritis. You might join if you have knee osteoarthritis in the more severe range (Kellgren-Lawrence grade 3–4) and meet safety requirements.
LjubljanaAges 45–100 - NCT07580222Recruiting
Using Mobile Technology to Track Knee Arthritis Health
This study uses smartphone or tablet technology to measure how your knee osteoarthritis (wear-and-tear arthritis) changes over time. You'll be helping researchers understand how well a previous arthritis treatment works by tracking your knee health at home.
Palo Alto, CaliforniaAges 30 years+ - NCT07580716RecruitingPhase 2
Knee Injection Treatment for Moderate Osteoarthritis
This study tests a new cell-based injection (Allocetra) directly into the knee joint for people with moderate osteoarthritis who haven't benefited from other treatments. The goal is to reduce pain and improve knee function.
Longwood, FloridaAges 64 years+ - NCT07581470Recruiting
Steroid Injection to Reduce Pain After Hip Replacement Surgery
This study tests whether adding a steroid medication (dexamethasone) through an IV line during hip replacement surgery reduces pain afterward. Researchers will compare three different doses to see which works best when combined with a nerve block (numbing medicine injected near the hip).
PoznanAges 18–100 - NCT07575425Recruiting
Balance Platform Exercises for Knee Osteoarthritis
This study tests whether special balance exercises on a moving platform can improve steadiness and walking in people with moderate knee osteoarthritis. The goal is to see if this type of training helps reduce pain and improve mobility.
AnkaraAges 45–65 - NCT06105788Recruiting
Exercise and pain relief for knee arthritis
This study looks at how moving your arms and legs might help reduce pain for people with knee osteoarthritis. If you join, you will do some light exercise so researchers can see if it helps your knee feel better.
El Paso, TexasAges 45–90 - NCT07544576Enrolling by invitationPhase 4
Knee Arthritis Injection: Two Injection Methods Compared
This study compares two ways of injecting a steroid medication into arthritic knees: using landmark guidance (traditional method) with a higher dose versus ultrasound guidance (imaging) with a lower dose. The goal is to see which approach works better to reduce knee pain and improve function.
Ventura, CaliforniaAges 50 years+ - NCT07547735RecruitingPhase 2
Stem Cell Treatment for Knee Osteoarthritis
This study tests whether special stem cells (called UC-MSCs, derived from umbilical cord tissue) can reduce pain and improve function in people with moderate knee osteoarthritis. Researchers will inject these cells into your knee to see if they help repair damaged cartilage and reduce inflammation.
WuhanAges 40–70 - NCT07544823Recruiting
Study of Early Markers for Osteoarthritis
This study looks for early signs of osteoarthritis (joint wear and tear) in your blood or other samples. Understanding these markers may help doctors detect and treat osteoarthritis sooner.
Xinxiang, HenanAges 40–70 - NCT07551245Recruiting
High-intensity laser vs traditional treatment for knee osteoarthritis
This study tests whether high-intensity laser therapy works better than traditional physical therapy methods for knee osteoarthritis pain and function. You'll be randomly assigned to receive either laser treatments or standard rehabilitation exercises.
Erbil, Erbil GovernorateAges 30–60 - NCT07542808RecruitingPhase 2/Phase 3
Stem cell treatment vs. hyaluronic acid for knee arthritis
This study tests whether an injection of stem cells (special cells that can help repair tissue) works better than a standard hyaluronic acid injection for knee osteoarthritis pain. Both treatments are injected into the knee to reduce pain and improve function.
Abu DhabiAges 18 years+ - NCT06748651RecruitingPhase 1
Allocetra injection for jaw joint arthritis
This study tests a new injection called Allocetra directly into the jaw joint to treat pain and inflammation in temporomandibular joint osteoarthritis. Eligible participants must have MRI-confirmed inflammation and meet basic health requirements.
Ramat GanAges 18–60 - NCT06753019Recruiting
Knee Osteoarthritis: Thoughts, Feelings, and Function
This study looks at how your thoughts and feelings about knee pain (and your daily function) relate to osteoarthritis. It aims to help understand your overall health better.
IspartaAges 40–84 - NCT07522489Recruiting
New knee replacement surgery guidance methods compared
This study compares two ways doctors use computer guidance during robotic knee replacement surgery for severe knee arthritis. The trial tests whether both methods work equally well or if one is better for patient recovery and results.
Warsaw, MazovianAges 18 years+ - NCT06762171Recruiting
Knee arthritis treatment for inner and front knee pain
This trial tests a treatment for people with knee arthritis affecting the inner and front parts of the knee. It aims to help relieve pain and improve function without needing a full knee replacement.
Sohag, Sohag GovernorateAges 35–60 - NCT07513415Recruiting
Injectable knee filler for osteoarthritis pain relief
This trial tests a new injectable filler called ALLOHEAL, injected directly into the knee joint to reduce pain and improve function in people with knee osteoarthritis. The filler is designed to cushion the knee joint and may help reduce pain and stiffness.
Uijeongbu-siAges 40–80 - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Escondido, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for osteoarthritis?
- Yes. Clin2 currently lists 592 recruiting osteoarthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a osteoarthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a osteoarthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.