Clinical trials
Overweight and Obese Adults clinical trials
Below are recruiting overweight and obese adults clinical trials, each written for real people, not researchers. We’re tracking 148 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07792954RecruitingPhase 3
Weekly weight-loss study for Chinese adults with overweight or obesity
This study tests a once-weekly medicine called PF-08653944 to see if it helps Chinese adults lose weight compared to a placebo (a pill with no active medicine). It may be an option if you have been unable to lose weight through diet alone.
Hefei, AnhuiAges 18 years+ - NCT07853898Recruiting
Pistachio snack trial for young adults with overweight
This study looks at how eating pistachios affects blood sugar and appetite after meals in young adults with overweight or obesity. Participants will eat pistachio snacks or a refined-carb snack and have blood tests to compare the effects.
St Louis, MissouriAges 18–35 - NCT07846033RecruitingPhase 1
Study of the experimental drug VK3019 for adults with overweight or obesity
This early-phase study tests an experimental medicine called VK3019 in adults who are overweight or have obesity but are otherwise healthy. The goal is to see if the drug is safe and how the body handles it, which may lead to future weight-management options.
Lake Forest, CaliforniaAges 18–60 - NCT07849439Recruiting
Stair-climbing exercise snacks for overweight young adults
This study tests whether short bursts of stair climbing (called 'exercise snacks') done twice a week can improve metabolic health in young adults with overweight or obesity. You'll be asked to do stair-climbing sessions and might also consume a meal-replacement shake, so the researchers can see how your body responds.
St Louis, MissouriAges 18–35 - NCT07802080Recruiting
Kettlebell and breathing exercises for lung health in overweight young adults
This study tests a 12-week program of kettlebell exercises combined with breathing exercises to see if it improves breathing muscle strength and lung function in young adults who are overweight or obese. If you are interested in improving your fitness, it may be a good option.
Phayao, Changwat PhayaoAges 18–25 - NCT07796971Recruiting
Exercise in low vs normal oxygen for weight and gut health
This study tests two exercise programs—one in low oxygen, one in normal oxygen—to see which is better at reducing body fat and improving gut health in adults aged 50–75 who are overweight or obese. You'll do high-intensity interval training (short bursts of intense exercise) and we'll monitor your results over time.
Bellerive-sur-AllierAges 50–75 - NCT07784270RecruitingPhase 3
Weight loss injection for adults with type 2 diabetes and overweight
This study tests a new injected medicine that may help people with type 2 diabetes and overweight or obesity lose weight. The trial will see how well it works and if it is safe compared to a placebo.
Fairhope, AlabamaAges 18 years+ - NCT07752979RecruitingPhase 2
New drug for weight loss in adults with obesity or overweight
This study tests an investigational drug called ABBV-295 to see if it helps adults with obesity or overweight who have weight-related health conditions lose weight. It may offer a new treatment option for managing weight and improving overall health.
Pelham, AlabamaAges 18–75 - NCT07743463RecruitingPhase 3
Daily pill for weight loss in adults with excess weight or weight-related health issues
This study tests a once-daily pill called ASC30 to help adults with obesity or overweight who also have conditions like high blood pressure, sleep apnea, or heart disease lose weight. The pill may work by affecting appetite and blood sugar, and the study aims to see how effective and safe it is.
Birmingham, AlabamaAges 18 years+ - NCT07743450RecruitingPhase 3
Daily oral medication for weight loss in adults with obesity and type 2 diabetes
This study tests a once-a-day pill for adults who are overweight or have obesity and also have type 2 diabetes. The goal is to see if the medication helps with weight loss and improves blood sugar control.
Birmingham, AlabamaAges 18 years+ - NCT07725809RecruitingPhase 1
Study of a new medicine for adults with overweight or obesity
This study tests a new medicine called PF-08653945 to see how it enters the blood in adults who are overweight or have obesity. The results will help doctors understand how the medicine works in the body.
Brussels, Bruxelles-capitale, Région deAges 18 years+ - NCT07728383RecruitingPhase 4
Obesity treatment study using tongue-applied semaglutide
This trial tests a new way to deliver semaglutide through a strip placed on the tongue for weight loss in adults with obesity. It may help you lose weight without a needle.
Minneapolis, MinnesotaAges 18–65 - NCT07721597RecruitingEarly Phase 1
Testing ZP6590 in Men of Various Weights
This trial tests an experimental medication called ZP6590 given as injections. It's for men who are at a normal weight, overweight, or have obesity, and studies how safe and well-tolerated the drug is in different doses.
Neuss, North Rhine-WestphaliaAges 18–60 - NCT07715955Recruiting
Can probiotics help control appetite in adults with overweight or obesity?
This study tests whether taking probiotics can help regulate appetite in people who are overweight or have obesity. It aims to understand if these supplements can support weight management by affecting hunger and fullness signals.
Maastricht, LimburgAges 20–70 - NCT07685808RecruitingPhase 2
Testing a weight loss injection for people with overweight or obesity
This study tests an injectable medication called Olatorepatide to help people with overweight or obesity lose weight. It is only for people without diabetes who meet specific body mass index (BMI) requirements.
Mobile, AlabamaAges 18 years+ - NCT07666425Recruiting
Understanding obesity types and treatment response
This study is following people with obesity to better understand different types of obesity and what affects treatment success. By joining, you help researchers learn which treatments work best for which people.
Bologna, BolognaAges 18 years+ - NCT06626360Recruiting
Screening for malnutrition in people with obesity
This study looks at whether overweight or obese patients may also be malnourished. Researchers will screen people with a BMI of 25 or higher to find hidden malnutrition so they can get the right nutritional support.
AmsterdamAges 18 years+ - NCT07654374RecruitingPhase 3
Study of a new pill for weight loss and diabetes
This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.
Birmingham, AlabamaAges 18–79 - NCT07654439Recruiting
Mixed reality tests for overweight and obese adults
This trial tests if mixed reality (combining real and virtual worlds) performance tests are valid and reliable for overweight and obese adults. You may be able to help researchers improve these tests if you are overweight or obese.
Konya, SelcukluAges 18–65 - NCT07597018RecruitingPhase 1
Comparing Blood Levels of Cagrilintide Versions in Adults With Overweight
This early-stage study tests different formulations of cagrilintide, a new medication, to see how the body absorbs and processes each version. Cagrilintide may help with weight management. Researchers will measure blood levels after you receive multiple doses.
BerlinAges 18–64 - NCT07594093RecruitingPhase 1
A study of REGN20934 for adults with overweight or obesity
This trial tests a new medication, REGN20934, to see how safe it is and how it works in the body for adults who are overweight or have obesity. It may help if you are looking for new treatment options.
Glendale, CaliforniaAges 18–65 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chandler, ArizonaAges 18–75 - NCT07582718Recruiting
High-Intensity Interval Training for Fitness in Adults
This study tests whether intense, short bursts of exercise can improve fitness in adults who are overweight. You'll do whole-body workouts designed to boost cardiovascular health and physical performance.
BrusselsAges 18–55 - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99
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Common questions
- Are there clinical trials for overweight and obese adults?
- Yes. Clin2 currently lists 148 recruiting overweight and obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight and obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight and obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.