Clinical trials
Overweight and Obese Adults clinical trials
Below are recruiting overweight and obese adults clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07245771RecruitingPhase 1/Phase 2
Weight loss study testing a new drug alone or with tirzepatide
This trial tests an experimental drug called RN3161 to see if it helps with weight loss in people with overweight or obesity. It can be taken alone or with another weight-loss medication (tirzepatide).
Melbourne, VictoriaAges 18–65 - NCT07307274RecruitingPhase 1
Safety study of SYNT-101 in healthy and overweight adults
This trial tests a new medicine called SYNT-101 in healthy and overweight adults to see if it is safe and how the body processes it. It may help researchers learn if this drug could be used for weight-related conditions in the future.
Bayswater, VictoriaAges 18–55 - NCT00428987Recruiting
Study of body and behavior traits in weight groups
This study looks at how physical traits and everyday behaviors differ among people who are overweight, obese, or in the normal-weight range. It may help researchers better understand risk factors related to weight and health.
Bethesda, MarylandAges 18–100 - NCT07441252RecruitingPhase 2
Study of maridebart cafraglutide for fatty liver with obesity
This trial tests a new medication (maridebart cafraglutide) to see if it can reduce fat in the liver and help with weight loss. It may be an option for adults with excess liver fat and obesity or overweight who haven't been able to lose weight with diet and exercise alone.
Chandler, ArizonaAges 18–99 - NCT07445503Recruiting
High phenolic olive oil for metabolic health in central obesity
This trial tests whether a special olive oil rich in natural plant compounds (polyphenols) can improve metabolic health in people with belly fat. You may be eligible if you are an adult with overweight or obesity and have at least one related health issue like high blood pressure, high blood sugar, or abnormal cholesterol.
KalamataAges 18–80 - NCT07465965RecruitingPhase 1
Weight loss study of semaglutide nasal spray in overweight or obese adults
This study tests a nasal spray containing semaglutide (a GLP-1 receptor agonist) to see if it helps adults who are overweight or obese lose weight. It may be an option if you have a BMI between 27 and 35 and have not used other weight loss medications recently.
Secaucus, New JerseyAges 18–65 - NCT07487376RecruitingPhase 1
A single-dose study of IBIO-600 in healthy overweight or obese adults
This trial tests a single dose of an experimental treatment called IBIO-600 to see if it's safe and how it works in overweight or obese adults. It's for people who are generally healthy and have a stable weight, without diabetes.
Bayswater, VictoriaAges 18–65 - NCT07582718Recruiting
High-Intensity Interval Training for Fitness in Adults
This study tests whether intense, short bursts of exercise can improve fitness in adults who are overweight. You'll do whole-body workouts designed to boost cardiovascular health and physical performance.
BrusselsAges 18–55 - NCT07589608RecruitingPhase 2
Weight Loss Study With Two New Injectable Medications
This study tests two new injectable drugs (macupatide and eloralintide) alone or together to help adults with obesity or excess weight lose weight. The goal is to see if these medications are safe and effective for weight management.
Chandler, ArizonaAges 18–75 - NCT07597018RecruitingPhase 1
Comparing Blood Levels of Cagrilintide Versions in Adults With Overweight
This early-stage study tests different formulations of cagrilintide, a new medication, to see how the body absorbs and processes each version. Cagrilintide may help with weight management. Researchers will measure blood levels after you receive multiple doses.
BerlinAges 18–64 - NCT07654439Recruiting
Mixed reality tests for overweight and obese adults
This trial tests if mixed reality (combining real and virtual worlds) performance tests are valid and reliable for overweight and obese adults. You may be able to help researchers improve these tests if you are overweight or obese.
Konya, SelcukluAges 18–65 - NCT07666425Recruiting
Understanding obesity types and treatment response
This study is following people with obesity to better understand different types of obesity and what affects treatment success. By joining, you help researchers learn which treatments work best for which people.
Bologna, BolognaAges 18 years+ - NCT07444736Enrolling by invitation
Exercise with blood flow restriction for adults with obesity
This study tests if adding blood flow restriction to resistance training can improve muscle strength and health in adults with obesity. It may help you build muscle more efficiently with lighter weights.
Tlajomulco de Zúñiga, JaliscoAges 18–30 - NCT07283406Enrolling by invitation
High-intensity interval training for young adults with obesity
This study tests whether high-intensity interval training (short bursts of intense exercise) can improve heart health and fitness in young adults with obesity. You would participate in a supervised exercise program to see if it helps lower your risk of future health problems.
Guadalajara, JaliscoAges 18–35 - NCT06996431Enrolling by invitation
Weight loss program with mobile health support
This study tests a new way to help adults lose weight using a smartphone app and health coaching. You might qualify if you are overweight, live in Hong Kong, speak Chinese, and can walk without help.
Hong KongAges 18 years+ - NCT05654337Recruiting
Lifestyle care program for overweight and obesity in primary care
This trial studies a new care approach (a pathway) for adults with overweight or obesity in local primary care clinics. It aims to help patients improve health through structured support, and it may be especially useful if you want guidance within routine clinic visits.
Ha'ilAges 18–60 - NCT07075146RecruitingPhase 3
Comparing two HIV treatments for people with overweight or obesity
This trial compares two different daily pill combinations for people newly starting HIV treatment who are overweight or have obesity. It aims to see which one works better for controlling the virus and managing weight.
Mexico CityAges 18–70 - NCT07317115Recruiting
Comparing a new surgery to a diabetes drug for weight loss
This trial compares a new surgical procedure (duodeno-ileostomy) to a medication (semaglutide) for people with obesity and type 2 diabetes. It aims to see which approach works better for weight loss and blood sugar control.
Westmount, QuebecAges 18 years+ - NCT06599918RecruitingPhase 2
Nicotinamide for liver scarring in fatty liver disease
This study tests whether nicotinamide (a form of vitamin B3) can help reduce liver scarring in people with nonalcoholic fatty liver disease. You may qualify if you have moderate to severe liver scarring and are between 18 and 85 years old.
BarcelonaAges 18–85 - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40 - NCT06830343RecruitingPhase 1
Safety study of SYH9017 for overweight and obesity
This study tests a new medication called SYH9017 for people who are overweight or have obesity. It aims to see how safe the drug is, how well it is tolerated, and how the body processes it. Participants will receive either the drug or a placebo and be monitored closely.
Beijing, Beijing MunicipalityAges 18–60 - NCT07638345Recruiting
AI-powered weight management for teens with diabetes or asthma
This study tests a smartphone app that uses artificial intelligence to help families manage weight and health for teenagers (ages 12–21) with Type 1 Diabetes or asthma. The app is designed to be personalized to each family's needs and may help improve overall health outcomes.
SevilleAges 18 years+ - NCT07497880RecruitingPhase 2
Study of a new pill for weight loss in adults with obesity
This trial tests a daily pill called KAI-7535 to see if it helps people with obesity or overweight lose weight safely. It is for adults who have a body mass index (BMI) of 27 or higher and at least one weight-related health problem, such as high blood pressure or type 2 diabetes.
Chandler, ArizonaAges 18–75 - NCT07049861Recruiting
Training program for primary care teams to help patients with weight and health
This trial trains healthcare providers how to better support patients with obesity using behavioral and nutrition counseling. The goal is to improve care for patients on Medicaid who have obesity.
St Louis, MissouriAges 5 years+
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Common questions
- Are there clinical trials for overweight and obese adults?
- Yes. Clin2 currently lists 139 recruiting overweight and obese adults studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight and obese adults trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight and obese adults trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.